Reversible changes in pancreatic islet structure and function produced by elevated blood glucose
Brereton, Melissa F., Iberl, Michaela, Shimomura, Kenju, Zhang, Quan, Adriaenssens, Alice E., Proks, Peter, Spiliotis, Ioannis I., Dace, William, Mattis, Katia K., Ramracheya, Reshma, Gribble, Fiona M., Reimann, Frank, Clark, Anne, Rorsman, Patrik, Ashcroft, Frances M.
Published in Nature communications (22.08.2014)
Published in Nature communications (22.08.2014)
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Journal Article
Binding of sulphonylureas to plasma proteins - A KATP channel perspective
Proks, Peter, Kramer, Holger, Haythorne, Elizabeth, Ashcroft, Frances M
Published in PloS one (01.05.2018)
Published in PloS one (01.05.2018)
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Journal Article
SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator
Aittoniemi, Jussi, Fotinou, Constantina, Craig, Tim J, de Wet, Heidi, Proks, Peter, Ashcroft, Frances M
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (27.01.2009)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (27.01.2009)
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Journal Article
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
Rödström, Karin E. J., Cloake, Alexander, Sörmann, Janina, Baronina, Agnese, Smith, Kathryn H. M., Pike, Ashley C. W., Ang, Jackie, Proks, Peter, Schewe, Marcus, Holland-Kaye, Ingelise, Bushell, Simon R., Elliott, Jenna, Pardon, Els, Baukrowitz, Thomas, Owens, Raymond J., Newstead, Simon, Steyaert, Jan, Carpenter, Elisabeth P., Tucker, Stephen J.
Published in Nature communications (16.05.2024)
Published in Nature communications (16.05.2024)
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Journal Article
Sulfonylurea Stimulation of Insulin Secretion
Proks, Peter, Reimann, Frank, Green, Nick, Gribble, Fiona, Ashcroft, Frances
Published in Diabetes (New York, N.Y.) (01.12.2002)
Published in Diabetes (New York, N.Y.) (01.12.2002)
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Journal Article
Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes
Gloyn, Anna L, Pearson, Ewan R, Antcliff, Jennifer F, Proks, Peter, Bruining, G. Jan, Slingerland, Annabelle S, Howard, Neville, Srinivasan, Shubha, Silva, José M.C.L, Molnes, Janne, Edghill, Emma L, Frayling, Timothy M, Temple, I. Karen, Mackay, Deborah, Shield, Julian P.H, Sumnik, Zdenek, van Rhijn, Adrian, Wales, Jerry K.H, Clark, Penelope, Gorman, Shaun, Aisenberg, Javier, Ellard, Sian, Njølstad, Pål R, Ashcroft, Frances M, Hattersley, Andrew T
Published in The New England journal of medicine (29.04.2004)
Published in The New England journal of medicine (29.04.2004)
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Journal Article
A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes
Proks, Peter, Arnold, Amanda L., Bruining, Jan, Girard, Christophe, Flanagan, Sarah E., Larkin, Brian, Colclough, Kevin, Hattersley, Andrew T., Ashcroft, Frances M., Ellard, Sian
Published in Human molecular genetics (01.06.2006)
Published in Human molecular genetics (01.06.2006)
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Journal Article
Molecular Basis of Kir6.2 Mutations Associated with Neonatal Diabetes or Neonatal Diabetes Plus Neurological Features
Proks, Peter, Antcliff, Jennifer F., Lippiat, Jon, Gloyn, Anna L., Hattersley, Andrew T., Ashcroft, Frances M., Stevens, Charles F.
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (14.12.2004)
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Journal Article
Identification of oxytocin receptor activating chemical components from traditional Japanese medicines
Maejima, Yuko, Horita, Shoichiro, Yokota, Shoko, Ono, Tomoyuki, Proks, Peter, Yoshida-Komiya, Hiromi, Ueta, Yoichi, Nishimori, Katsuhiko, Misaka, Shingen, Shimomura, Kenju
Published in Journal of food and drug analysis (15.12.2021)
Published in Journal of food and drug analysis (15.12.2021)
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Journal Article
A Mouse Model of Human Hyperinsulinism Produced by the E1506K Mutation in the Sulphonylurea Receptor SUR1
SHIMOMURA, Kenju, TUSA, Maija, USTINOV, Jarkko, OTONKOSKI, Timo, LAAKSO, Markku, ASHCROFT, Frances M, IBERL, Michaela, BRERETON, Melissa F, KAIZIK, Stephan, PROKS, Peter, LAHMANN, Carolina, YALURI, Nagendra, MODI, Shalem, HUOPIO, Hanna
Published in Diabetes (New York, N.Y.) (01.11.2013)
Published in Diabetes (New York, N.Y.) (01.11.2013)
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Journal Article
How ATP Inhibits the Open KATP Channel
Craig, Tim J., Ashcroft, Frances M., Proks, Peter
Published in The Journal of general physiology (01.07.2008)
Published in The Journal of general physiology (01.07.2008)
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Journal Article
A Proposal of Combined Evaluation of Waist Circumference and BMI for the Diagnosis of Metabolic Syndrome
TAKAHASHI, Masaki, SHIMOMURA, Kenju, PROKS, Peter, CRAIG, Timothy J., NEGISHI, Mayumi, AKUZAWA, Masako, HAYASHI, Rikuro, SHIMOMURA, Yohnosuke, KOBAYASHI, Isao
Published in ENDOCRINE JOURNAL (2009)
Published in ENDOCRINE JOURNAL (2009)
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Journal Article
Phentolamine block of KATP channels is mediated by Kir6.2
Proks, P, Ashcroft, F M
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (14.10.1997)
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Journal Article
Mutations at the Same Residue (R50) of Kir6.2 (KCNJ11) That Cause Neonatal Diabetes Produce Different Functional Effects
SHIMOMURA, Kenju, GIRARD, Christophe A. J, ASHCROFT, Frances M, PROKS, Peter, NAZIM, Joanna, LIPPIAT, Jonathan D, CERUTTI, Franco, LORINI, Renata, ELLARD, Sian, HATTERSELY, Andrew T, BARBETTI, Fabrizio
Published in Diabetes (New York, N.Y.) (01.06.2006)
Published in Diabetes (New York, N.Y.) (01.06.2006)
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Journal Article