Metabolomics: A tool for early detection of toxicological effects and an opportunity for biology based grouping of chemicals—From QSAR to QBAR
van Ravenzwaay, B., Herold, M., Kamp, H., Kapp, M.D., Fabian, E., Looser, R., Krennrich, G., Mellert, W., Prokoudine, A., Strauss, V., Walk, T., Wiemer, J.
Published in Mutation research (15.08.2012)
Published in Mutation research (15.08.2012)
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Journal Article
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma
Mattes, W., Davis, K., Fabian, E., Greenhaw, J., Herold, M., Looser, R., Mellert, W., Groeters, S., Marxfeld, H., Moeller, N., Montoya-Parra, G., Prokoudine, A., van Ravenzwaay, B., Strauss, V., Walk, T., Kamp, H.
Published in Toxicology letters (04.11.2014)
Published in Toxicology letters (04.11.2014)
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Journal Article
The use of metabolomics for the discovery of new biomarkers of effect
van Ravenzwaay, B., Cunha, G. Coelho-Palermo, Leibold, E., Looser, R., Mellert, W., Prokoudine, A., Walk, T., Wiemer, J.
Published in Toxicology letters (30.07.2007)
Published in Toxicology letters (30.07.2007)
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Journal Article
Conference Proceeding
Nutritional impact on the plasma metabolome of rats
Mellert, W., Kapp, M., Strauss, V., Wiemer, J., Kamp, H., Walk, T., Looser, R., Prokoudine, A., Fabian, E., Krennrich, G., Herold, M., van Ravenzwaay, B.
Published in Toxicology letters (30.11.2011)
Published in Toxicology letters (30.11.2011)
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Journal Article
Reproducibility and robustness of metabolome analysis in rat plasma of 28-day repeated dose toxicity studies
Kamp, H., Strauss, V., Wiemer, J., Leibold, E., Walk, T., Mellert, W., Looser, R., Prokoudine, A., Fabian, E., Krennrich, G., Herold, M., van Ravenzwaay, B.
Published in Toxicology letters (30.11.2012)
Published in Toxicology letters (30.11.2012)
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Journal Article
Increased toxicity when fibrates and statins are administered in combination – A metabolomics approach with rats
Strauss, V., Mellert, W., Wiemer, J., Leibold, E., Kamp, H., Walk, T., Looser, R., Prokoudine, A., Fabian, E., Krennrich, G., Herold, M., van Ravenzwaay, B.
Published in Toxicology letters (01.06.2012)
Published in Toxicology letters (01.06.2012)
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Journal Article
Prediction of Clinically Relevant Safety Signals of Nephrotoxicity through Plasma Metabolite Profiling
Strauss, V., van Ravenzwaay, B., Walk, T., Omura, K., Schuppe-Koistinen, I., Nadanaciva, S., Bush, E. D., Moeller, N., Ruiz-Noppinger, Patricia, Piccoli, S. P., Prokoudine, A., Mellert, W., Looser, R., Krennrich, G., Herold, M., Fabian, E., Kamp, H. G., Mattes, W. B., Naraoka, H.
Published in BioMed research international (01.01.2013)
Published in BioMed research international (01.01.2013)
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Journal Article
The individual and combined metabolite profiles (metabolomics) of dibutylphthalate and di(2-ethylhexyl)phthalate following a 28-day dietary exposure in rats
van Ravenzwaay, B., Coelho-Palermo Cunha, G., Strauss, V., Wiemer, J., Leibold, E., Kamp, H., Walk, T., Mellert, W., Looser, R., Prokoudine, A., Fabian, E., Krennrich, G., Herold, M.
Published in Toxicology letters (05.10.2010)
Published in Toxicology letters (05.10.2010)
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Journal Article
Application of in vivo metabolomics to preclinical/toxicological studies: case study on phenytoin-induced systemic toxicity
Kamp, H, Fabian, E, Groeters, S, Herold, M, Krennrich, G, Looser, R, Mattes, W, Mellert, W, Prokoudine, A, Ruiz-Noppinger, P, Strauss, V, Walk, T, Wiemer, J, van Ravenzwaay, B
Published in Bioanalysis (01.09.2012)
Published in Bioanalysis (01.09.2012)
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Journal Article
Influence of strain and sex on the metabolic profile of rats in repeated dose toxicological studies
Strauss, V., Wiemer, J., Leibold, E., Kamp, H., Walk, T., Mellert, W., Looser, R., Prokoudine, A., Fabian, E., Krennrich, G., Herold, M., van Ravenzwaay, B.
Published in Toxicology letters (01.12.2009)
Published in Toxicology letters (01.12.2009)
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Journal Article
Metabolomics and REACH: quantitative biological activity relationships
van Ravenzwaay, Bennard, Herold, M., Kamp, Hennicke, Montoya, Gina, Fabian, Eric, Looser, Ralf, Krennrich, G., Mellert, Werner, Prokoudine, A., Strauss, Volker, Walk, Tilmann, Wiemer, J.
Published in Toxicology letters (28.08.2013)
Published in Toxicology letters (28.08.2013)
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Journal Article
Metabolomics in vivo as a tool for chemical grouping under reach
Kamp, H., Herold, M., Fabian, E.J., Looser, R., Krenrich, G., Mellert, W., Prokoudine, A., Strauss, V.
Published in Toxicology letters (28.08.2011)
Published in Toxicology letters (28.08.2011)
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Journal Article
Metabolite profiling—A new tool for the identification of toxicological effects of chemicals
Kamp, Hennicke, Buesen, Roland, Cunha, Georgia Coelho-Palermo, Fabian, Eric, Fischer, Wolfgang, Herold, Michael, Leibold, Edgar, Looser, Ralf, Krennrich, Gerhard, Mellert, Werner, Nishino, Tsuyuki, Prokoudine, Alexandre, Strauss, Volker, Walk, Tilmann, Wiemer, Jan, van Ravenzwaay, Bennard
Published in Toxicology letters (13.09.2009)
Published in Toxicology letters (13.09.2009)
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Journal Article
Means and methods for assessing hematopoietic toxicity
FABIAN ERIC, LOOSER RALF, STRAUSS VOLKER, RAVENZWAAY BENNARD VAN, MELLERT WERNER, PROKOUDINE ALEXANDRE, WALK TILMANN B, WIEMER JAN C, HEROLD MICHAEL MANFRED, KAMP HENNICKE
Year of Publication 26.10.2016
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Year of Publication 26.10.2016
Patent
MEANS AND METHODS FOR ASSESSING KIDNEY TOXICITY
FABIAN ERIC, LOOSER RALF, STRAUSS VOLKER, RAVENZWAAY BENNARD VAN, MELLERT WERNER, PROKOUDINE ALEXANDRE, WALK TILMANN B, WIEMER JAN C, HEROLD MICHAEL MANFRED, KAMP HENNICKE
Year of Publication 12.10.2016
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Year of Publication 12.10.2016
Patent
Plants with increased yield
GROTH PHILIP, KULKARNI RESHAM, RITTE GERHARD, KOLLIPARA KRISHNA, PROKOUDINE ALEXANDRE, HENDRIKS JANNEKE, THIMM OLIVER, KOENIG CLAUDIA
Year of Publication 11.07.2012
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Year of Publication 11.07.2012
Patent
Means and methods for assessing hematopoietic toxicity
FABIAN ERIC, LOOSER RALF, STRAUSS VOLKER, RAVENZWAAY BENNARD VAN, MELLERT WERNER, PROKOUDINE ALEXANDRE, WALK TILMANN B, WIEMER JAN C, HEROLD MICHAEL MANFRED, KAMP HENNICKE
Year of Publication 28.05.2014
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Year of Publication 28.05.2014
Patent
Means and methods for assessing kidney toxicity
FABIAN ERIC, LOOSER RALF, STRAUSS VOLKER, RAVENZWAAY BENNARD VAN, MELLERT WERNER, PROKOUDINE ALEXANDRE, WALK TILMANN B, WIEMER JAN C, HEROLD MICHAEL MANFRED, KAMP HENNICKE
Year of Publication 21.05.2014
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Year of Publication 21.05.2014
Patent
Means and methods for assessing gonadal toxicity
FABIAN ERIC, LOOSER RALF, STRAUSS VOLKER, RAVENZWAAY BENNARD VAN, MELLERT WERNER, PROKOUDINE ALEXANDRE, WALK TILMANN B, WIEMER JAN C, HEROLD MICHAEL MANFRED, KAMP HENNICKE
Year of Publication 14.05.2014
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Year of Publication 14.05.2014
Patent
Means and methods for diagnosingthyroid disorders
FABIAN ERIC, LOOSER RALF, LEIBOLD EDGAR, STRAUSS VOLKER, VAN RAVENZWAAY BENNARD, WALK TILMANN, MELLERT WERNER, PROKOUDINE ALEXANDRE, COELHO PALERMO CUNHA GEORGIA, WIEMER JAN C, HEROLD MICHAEL MANFRED, KAMP HENNICKE
Year of Publication 23.05.2012
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Year of Publication 23.05.2012
Patent