Differential distribution of voltage-gated calcium channel alpha-2 delta (α2δ) subunit mRNA-containing cells in the rat central nervous system and the dorsal root ganglia
Cole, Rebecca L., Lechner, Sandra M., Williams, Mark E., Prodanovich, Pat, Bleicher, Leo, Varney, Mark A., Gu, Guibao
Published in Journal of comparative neurology (1911) (24.10.2005)
Published in Journal of comparative neurology (1911) (24.10.2005)
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Journal Article
5-Lipoxygenase-activating protein inhibitors. Part 2: 3-{5-(( S)-1-Acetyl-2,3-dihydro-1 H-indol-2-ylmethoxy)-3- tert-butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl]-1 H-indol-2-yl}-2,2-dimethyl-propionic acid (AM679)—A potent FLAP inhibitor
Stock, Nicholas, Baccei, Christopher, Bain, Gretchen, Broadhead, Alex, Chapman, Charles, Darlington, Janice, King, Christopher, Lee, Catherine, Li, Yiwei, Lorrain, Daniel S., Prodanovich, Pat, Rong, Haojing, Santini, Angelina, Zunic, Jasmine, Evans, Jilly F., Hutchinson, John H., Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Journal Article
Pharmacological Characterization of 3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic Acid (AM103), a Novel Selective 5-Lipoxygenase-Activating Protein Inhibitor That Reduces Acute and Chronic Inflammation
Lorrain, Daniel S, Bain, Gretchen, Correa, Lucia D, Chapman, Charles, Broadhead, Alex R, Santini, Angelina M, Prodanovich, Pat, Darlington, Janice V, Hutchinson, John H, King, Christopher, Lee, Catherine, Baccei, Christopher, Li, Yiwei, Arruda, Jeannie M, Evans, Jilly F
Published in The Journal of pharmacology and experimental therapeutics (01.12.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2009)
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Journal Article
Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX
Hutchinson, John H, Rowbottom, Martin W, Lonergan, David, Darlington, Janice, Prodanovich, Pat, King, Christopher D, Evans, Jilly F, Bain, Gretchen
Published in ACS medicinal chemistry letters (13.04.2017)
Published in ACS medicinal chemistry letters (13.04.2017)
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Journal Article
Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding
Stein, Adam J, Bain, Gretchen, Prodanovich, Pat, Santini, Angelina M, Darlington, Janice, Stelzer, Nina M P, Sidhu, Ranjinder S, Schaub, Jeffrey, Goulet, Lance, Lonergan, Dave, Calderon, Imelda, Evans, Jilly F, Hutchinson, John H
Published in Molecular pharmacology (01.12.2015)
Published in Molecular pharmacology (01.12.2015)
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Journal Article
Differential distribution of voltage-gated calcium channel alpha-2 delta ( alpha sub(2) delta ) subunit mRNA-containing cells in the rat central nervous system and the dorsal root ganglia
Cole, Rebecca L, Lechner, Sandra M, Williams, Mark E, Prodanovich, Pat, Bleicher, Leo, Varney, Mark A, Gu, Guibao
Published in Journal of comparative neurology (1911) (24.10.2005)
Published in Journal of comparative neurology (1911) (24.10.2005)
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Journal Article
5-Lipoxygenase-Activating Protein (FLAP) Inhibitors. Part 4: Development of 3-[3-tert-Butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic Acid (AM803), a Potent, Oral, Once Daily FLAP Inhibitor
Stock, Nicholas S, Bain, Gretchen, Zunic, Jasmine, Li, Yiwei, Ziff, Jeannie, Roppe, Jeffrey, Santini, Angelina, Darlington, Janice, Prodanovich, Pat, King, Christopher D, Baccei, Christopher, Lee, Catherine, Rong, Haojing, Chapman, Charles, Broadhead, Alex, Lorrain, Dan, Correa, Lucia, Hutchinson, John H, Evans, Jilly F, Prasit, Peppi
Published in Journal of medicinal chemistry (08.12.2011)
Published in Journal of medicinal chemistry (08.12.2011)
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Journal Article
5-Lipoxygenase-Activating Protein (FLAP) Inhibitors. Part 4: Development of 3-[3- tert -Butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethylpropionic Acid (AM803), a Potent, Oral, Once Daily FLAP Inhibitor
Stock, Nicholas S., Bain, Gretchen, Zunic, Jasmine, Li, Yiwei, Ziff, Jeannie, Roppe, Jeffrey, Santini, Angelina, Darlington, Janice, Prodanovich, Pat, King, Christopher D., Baccei, Christopher, Lee, Catherine, Rong, Haojing, Chapman, Charles, Broadhead, Alex, Lorrain, Dan, Correa, Lucia, Hutchinson, John H., Evans, Jilly F., Prasit, Peppi
Published in Journal of medicinal chemistry (08.12.2011)
Published in Journal of medicinal chemistry (08.12.2011)
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Journal Article
Pharmacology of AM211, a Potent and Selective Prostaglandin D 2 Receptor Type 2 Antagonist That Is Active in Animal Models of Allergic Inflammation
Bain, Gretchen, Lorrain, Daniel S., Stebbins, Karin J., Broadhead, Alex R., Santini, Angelina M., Prodanovich, Pat, Darlington, Janice, King, Christopher D., Lee, Catherine, Baccei, Christopher, Stearns, Brian, Troung, Yen, Hutchinson, John H., Prasit, Peppi, Evans, Jilly F.
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
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Journal Article
5-Lipoxygenase-Activating Protein Inhibitors: Development of 3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic Acid (AM103)
Hutchinson, John H, Li, Yiwei, Arruda, Jeannie M, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher D, Lee, Catherine, Lorrain, Dan, Prodanovich, Pat, Rong, Haojing, Santini, Angelina, Stock, Nicholas, Prasit, Peppi, Evans, Jilly F
Published in Journal of medicinal chemistry (08.10.2009)
Published in Journal of medicinal chemistry (08.10.2009)
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Journal Article
Pharmacology of AM211, a potent and selective prostaglandin D2 receptor type 2 antagonist that is active in animal models of allergic inflammation
Bain, Gretchen, Lorrain, Daniel S, Stebbins, Karin J, Broadhead, Alex R, Santini, Angelina M, Prodanovich, Pat, Darlington, Janice, King, Christopher D, Lee, Catherine, Baccei, Christopher, Stearns, Brian, Troung, Yen, Hutchinson, John H, Prasit, Peppi, Evans, Jilly F
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2011)
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Journal Article
Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitis
STEARNS, Brian A, BACCEI, Christopher, LEE, Catherine, LORRAIN, Daniel S, PRASIT, Peppi, PRODANOVICH, Pat, SANTINI, Angelina, SCOTT, Jill M, STOCK, Nicholas S, TRUONG, Yen P, BAIN, Gretchen, BROADHEAD, Alex, CLARK, Ryan C, COATE, Heather, EVANS, Jilly F, FAGAN, Patrick, HUTCHINSON, John H, KING, Christopher
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Journal Article
Discovery and optimization of a biphenylacetic acid series of prostaglandin D 2 receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis
Scott, Jill M., Baccei, Christopher, Bain, Gretchen, Broadhead, Alex, Evans, Jilly F., Fagan, Patrick, Hutchinson, John H., King, Christopher, Lorrain, Daniel S., Lee, Catherine, Prasit, Peppi, Prodanovich, Pat, Santini, Angelina, Stearns, Brian A.
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
Sodium [2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D 2 receptor antagonist
Stock, Nicholas, Volkots, Deborah, Stebbins, Karin, Broadhead, Alex, Stearns, Brian, Roppe, Jeffrey, Parr, Timothy, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher, Lee, Catherine, Lorrain, Daniel S., Prodanovich, Pat, Santini, Angelina, Evans, Jilly F., Hutchinson, John H., Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
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Journal Article
Sodium [2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): A potent, selective prostaglandin D₂ receptor antagonist
Stock, Nicholas, Volkots, Deborah, Stebbins, Karin, Broadhead, Alex, Stearns, Brian, Roppe, Jeffrey, Parr, Timothy, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher, Lee, Catherine, Lorrain, Daniel S, Prodanovich, Pat, Santini, Angelina, Evans, Jilly F, Hutchinson, John H, Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
Published in Bioorganic & medicinal chemistry letters (01.02.2011)
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Journal Article
Discovery and optimization of a biphenylacetic acid series of prostaglandin D sub(2 receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis)
Scott, Jill M, Baccei, Christopher, Bain, Gretchen, Broadhead, Alex, Evans, Jilly F, Fagan, Patrick, Hutchinson, John H, King, Christopher, Lorrain, Daniel S, Lee, Catherine, Prasit, Peppi, Prodanovich, Pat, Santini, Angelina, Stearns, Brian A
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
5-Lipoxygenase-activating protein inhibitors. Part 3: 3-{3-tert-Butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl]-5-(5-methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM643)—A potent FLAP inhibitor suitable for topical administration
Stock, Nicholas, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher, Lee, Catherine, Lorrain, Daniel S., Prodanovich, Pat, Santini, Angelina, Schaab, Kevin, Evans, Jilly F., Hutchinson, John H., Prasit, Peppi
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Discovery and optimization of a biphenylacetic acid series of prostaglandin D₂ receptor DP2 antagonists with efficacy in a murine model of allergic rhinitis
Scott, Jill M, Baccei, Christopher, Bain, Gretchen, Broadhead, Alex, Evans, Jilly F, Fagan, Patrick, Hutchinson, John H, King, Christopher, Lorrain, Daniel S, Lee, Catherine, Prasit, Peppi, Prodanovich, Pat, Santini, Angelina, Stearns, Brian A
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
Pharmacological Characterization of 3-[3- tert -Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethyl-propionic Acid (AM103), a Novel Selective 5-Lipoxygenase-Activating Protein Inhibitor That Reduces Acute and Chronic Inflammation
Lorrain, Daniel S., Bain, Gretchen, Correa, Lucia D., Chapman, Charles, Broadhead, Alex R., Santini, Angelina M., Prodanovich, Pat, Darlington, Janice V., Hutchinson, John H., King, Christopher, Lee, Catherine, Baccei, Christopher, Li, Yiwei, Arruda, Jeannie M., Evans, Jilly F.
Published in The Journal of pharmacology and experimental therapeutics (01.12.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2009)
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Journal Article
5-Lipoxygenase-Activating Protein Inhibitors: Development of 3-[3- tert -Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethyl-propionic Acid (AM103)
Hutchinson, John H., Li, Yiwei, Arruda, Jeannie M., Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher D., Lee, Catherine, Lorrain, Dan, Prodanovich, Pat, Rong, Haojing, Santini, Angelina, Stock, Nicholas, Prasit, Peppi, Evans, Jilly F.
Published in Journal of medicinal chemistry (08.10.2009)
Published in Journal of medicinal chemistry (08.10.2009)
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Journal Article