Mesenchymal Stem Cell Protection of Neurons against Glutamate Excitotoxicity Involves Reduction of NMDA-Triggered Calcium Responses and Surface GluR1, and Is Partly Mediated by TNF
Papazian, Irini, Kyrargyri, Vasiliki, Evangelidou, Maria, Voulgari-Kokota, Anda, Probert, Lesley
Published in International journal of molecular sciences (25.02.2018)
Published in International journal of molecular sciences (25.02.2018)
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Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice
Papazian, Irini, Tsoukala, Eleni, Boutou, Athena, Karamita, Maria, Kambas, Konstantinos, Iliopoulou, Lida, Fischer, Roman, Kontermann, Roland E, Denis, Maria C, Kollias, George, Lassmann, Hans, Probert, Lesley
Published in Journal of neuroinflammation (26.09.2021)
Published in Journal of neuroinflammation (26.09.2021)
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Novel cell-based analysis reveals region-dependent changes in microglial dynamics in grey matter in a cuprizone model of demyelination
Roufagalas, Ilias, Avloniti, Maria, Fortosi, Alexandra, Xingi, Evangelia, Thomaidou, Dimitra, Probert, Lesley, Kyrargyri, Vasiliki
Published in Neurobiology of disease (01.09.2021)
Published in Neurobiology of disease (01.09.2021)
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IKKβ deletion from CNS macrophages increases neuronal excitability and accelerates the onset of EAE, while from peripheral macrophages reduces disease severity
Avloniti, Maria, Evangelidou, Maria, Gomini, Maria, Loupis, Theodore, Emmanouil, Mary, Mitropoulou, Adamantia, Tselios, Theodore, Lassmann, Hans, Gruart, Agnès, Delgado-García, José M, Probert, Lesley, Kyrargyri, Vasiliki
Published in Journal of neuroinflammation (27.01.2024)
Published in Journal of neuroinflammation (27.01.2024)
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Editorial: Update on Translational Neuroimmunology - Research of ISNI 2018
Probert, Lesley, Quintana, Francisco J, Bar-Or, Amit
Published in Frontiers in immunology (30.09.2020)
Published in Frontiers in immunology (30.09.2020)
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Conference Proceeding
Spontaneous human CD8 T cell and autoimmune encephalomyelitis-induced CD4/CD8 T cell lesions in the brain and spinal cord of HLA-DRB115-positive multiple sclerosis humanized immune system mice
Papazian, Irini, Kourouvani, Maria, Dagkonaki, Anastasia, Gouzouasis, Vasileios, Dimitrakopoulou, Lila, Markoglou, Nikolaos, Badounas, Fotis, Tselios, Theodore, Anagnostouli, Maria, Probert, Lesley
Published in eLife (20.06.2024)
Published in eLife (20.06.2024)
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Microglia regulate cortical remyelination via TNFR1-dependent phenotypic polarization
Boutou, Athena, Roufagalas, Ilias, Politopoulou, Katerina, Tastsoglou, Spyros, Abouzeid, Maya, Skoufos, Giorgos, Verdu de Juan, Laia, Ko, Jeong Hun, Kyrargyri, Vasiliki, Hatzigeorgiou, Artemis G., Barnum, Christopher J., Tesi, Raymond J., Bauer, Jan, Lassmann, Hans, Johnson, Michael R., Probert, Lesley
Published in Cell reports (Cambridge) (26.11.2024)
Published in Cell reports (Cambridge) (26.11.2024)
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Maturation of circulating Ly6ChiCCR2+ monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis
Dagkonaki, Anastasia, Papalambrou, Athina, Avloniti, Maria, Gkika, Areti, Evangelidou, Maria, Androutsou, Maria-Eleni, Tselios, Theodore, Probert, Lesley
Published in Frontiers in immunology (09.09.2022)
Published in Frontiers in immunology (09.09.2022)
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Increased Citrullination of Histone H3 in Multiple Sclerosis Brain and Animal Models of Demyelination: A Role for Tumor Necrosis Factor-Induced Peptidylarginine Deiminase 4 Translocation
Mastronardi, Fabrizio G, Wood, D. Denise, Mei, Jiang, Raijmakers, Reinout, Tseveleki, Vivian, Dosch, Hans-Michael, Probert, Lesley, Casaccia-Bonnefil, Patrizia, Moscarello, Mario A
Published in The Journal of neuroscience (01.11.2006)
Published in The Journal of neuroscience (01.11.2006)
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Characterization of Asparagine Deamidation in Immunodominant Myelin Oligodendrocyte Glycoprotein Peptide Potential Immunotherapy for the Treatment of Multiple Sclerosis
Androutsou, Maria-Eleni, Nteli, Agathi, Gkika, Areti, Avloniti, Maria, Dagkonaki, Anastasia, Probert, Lesley, Tselios, Theodore, Golič Grdadolnik, Simona
Published in International journal of molecular sciences (13.10.2020)
Published in International journal of molecular sciences (13.10.2020)
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A Cyclic Altered Peptide Analogue Based on Myelin Basic Protein 87-99 Provides Lasting Prophylactic and Therapeutic Protection Against Acute Experimental Autoimmune Encephalomyelitis
Emmanouil, Mary, Tseveleki, Vivian, Triantafyllakou, Iro, Nteli, Agathi, Tselios, Theodore, Probert, Lesley
Published in Molecules (Basel, Switzerland) (31.01.2018)
Published in Molecules (Basel, Switzerland) (31.01.2018)
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Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions
Dagkonaki, Anastasia, Avloniti, Maria, Evangelidou, Maria, Papazian, Irini, Kanistras, Ioannis, Tseveleki, Vivian, Lampros, Fotis, Tselios, Theodore, Jensen, Lise Torp, Möbius, Wiebke, Ruhwedel, Torben, Androutsou, Maria-Eleni, Matsoukas, John, Anagnostouli, Maria, Lassmann, Hans, Probert, Lesley
Published in Frontiers in immunology (19.11.2020)
Published in Frontiers in immunology (19.11.2020)
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Comparative gene expression analysis in mouse models for multiple sclerosis, Alzheimer's disease and stroke for identifying commonly regulated and disease-specific gene changes
Tseveleki, Vivian, Rubio, Renee, Vamvakas, Sotiris-Spyros, White, Joseph, Taoufik, Era, Petit, Edwige, Quackenbush, John, Probert, Lesley
Published in Genomics (San Diego, Calif.) (01.08.2010)
Published in Genomics (San Diego, Calif.) (01.08.2010)
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Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia
Karamita, Maria, Barnum, Christopher, Möbius, Wiebke, Tansey, Malú G, Szymkowski, David E, Lassmann, Hans, Probert, Lesley
Published in JCI insight (20.04.2017)
Published in JCI insight (20.04.2017)
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A National Representative, Cross-Sectional Study by the Hellenic Academy of NeuroImmunology (HEL.A.NI.) on COVID-19 and Multiple Sclerosis: Overall Impact and Willingness Toward Vaccination
Boziki, Marina, Styliadis, Charis, Bakirtzis, Christos, Grigoriadou, Eleni, Sintila, Aggeliki-Styliani, Nikolaidis, Ioannis, Vrienniou, Aliki, Geys, Lotte, Pelidou, Sygkliti-Henrietta, Probert, Lesley, Papazisis, Georgios, Bamidis, Panagiotis, Grigoriadis, Nikolaos
Published in Frontiers in neurology (25.11.2021)
Published in Frontiers in neurology (25.11.2021)
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Exploiting the Role of Hypoxia-Inducible Factor 1 and Pseudohypoxia in the Myelodysplastic Syndrome Pathophysiology
Stergiou, Ioanna E, Kambas, Konstantinos, Poulaki, Aikaterini, Giannouli, Stavroula, Katsila, Theodora, Dimitrakopoulou, Aglaia, Vidali, Veroniki, Mouchtouris, Vasileios, Kloukina, Ismini, Xingi, Evangelia, Pagakis, Stamatis N, Probert, Lesley, Patrinos, George P, Ritis, Konstantinos, Tzioufas, Athanasios G, Voulgarelis, Michael
Published in International journal of molecular sciences (15.04.2021)
Published in International journal of molecular sciences (15.04.2021)
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TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury
Taoufik, Era, Petit, Edwige, Divoux, Didier, Tseveleki, Vivian, Mengozzi, Manuela, Roberts, Michael L, Valable, Samuel, Ghezzi, Pietro, Quackenbush, John, Brines, Michael, Cerami, Anthony, Probert, Lesley
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (22.04.2008)
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Interleukin 6 is required for the development of collagen-induced arthritis
Alonzi, T, Fattori, E, Lazzaro, D, Costa, P, Probert, L, Kollias, G, De Benedetti, F, Poli, V, Ciliberto, G
Published in The Journal of experimental medicine (16.02.1998)
Published in The Journal of experimental medicine (16.02.1998)
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