Synthesis and pharmacological evaluation of 4a-phenanthrenamine derivatives acting at the phencyclidine binding site of the N-methyl-D-aspartate receptor complex
Bigge, Christopher F, Malone, Thomas C, Hays, Sheryl J, Johnson, Graham, Novak, Perry M, Lescosky, Leonard J, Retz, Daniel M, Ortwine, Daniel F, Probert, Albert W
Published in Journal of medicinal chemistry (01.07.1993)
Published in Journal of medicinal chemistry (01.07.1993)
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Exploration of N-phosphonoalkyl-, N-phosphonoalkenyl-, and N-(phosphonoalkyl)phenyl-spaced .alpha.-amino acids as competitive N-methyl-D-aspartic acid antagonists
Bigge, Christopher F, Johnson, Graham, Ortwine, Daniel F, Drummond, James T, Retz, Daniel M, Brahce, Laura J, Coughenour, Linda L, Marcoux, Frank W, Probert, Albert W
Published in Journal of medicinal chemistry (01.04.1992)
Published in Journal of medicinal chemistry (01.04.1992)
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Exploration of phenyl-spaced 2-amino-(5-9)-phosphonoalkanoic acids as competitive N-methyl-D-aspartic acid antagonists
Bigge, Christopher F, Drummond, James T, Johnson, Graham, Malone, Thomas, Probert, Albert W, Marcoux, Frank W, Coughenour, Linda L, Brahce, Laura J
Published in Journal of medicinal chemistry (01.07.1989)
Published in Journal of medicinal chemistry (01.07.1989)
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Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells
Nath, Rathna, Davis, Megan, Probert, Albert W., Kupina, Nancy C., Ren, Xiaodong, Schielke, Gerald P., Wang, Kevin K.W.
Published in Biochemical and biophysical research communications (21.07.2000)
Published in Biochemical and biophysical research communications (21.07.2000)
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Exploration of phenyl-spaced 2-amino-(5-9)-phosphonoalkanoic acids as competitive N-methyl-D-aspartic acid antagonists [Erratum to document cited in CA111(3):23931d]
Bigge, Christopher F, Drummond, James T, Johnson, Graham, Malone, Thomas, Probert, Albert W, Marcoux, Frank W, Coughenour, Linda L, Brahce, Laura J
Published in Journal of medicinal chemistry (01.12.1989)
Published in Journal of medicinal chemistry (01.12.1989)
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An Alpha-Mercaptoacrylic Acid Derivative is a Selective Nonpeptide Cell-Permeable Calpain Inhibitor and is Neuroprotective
Kevin K. W. Wang, Nath, Rathna, Posner, Avigail, Raser, Kadee J., Buroker-Kilgore, Michelle, Hajimohammadreza, Iradj, Probert, Albert W., Marcoux, Frank W., Ye, Qizhuang, Takano, Emiko, Hatanaka, Masakazu, Maki, Masatoshi, Caner, Hakan, Collins, Jennifer L., Fergus, Andrea, Lee, Kevin S., Lunney, Elizabeth A., Hays, Sheryl J., Yuen, Po-Wai
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (25.06.1996)
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The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases
Hu, Lain-Yen, Boxer, Peter A., Kesten, Suzanne R., Lei, Huangshu J., Wustrow, David J., Moreland, David W., Zhang, Liming, Ahn, Kay, Ryder, Todd R., Liu, Xiaohong, Rubin, John R., Fahnoe, Kelly, Carroll, Richard T., Dutta, Satavisha, Fahnoe, Douglass C., Probert, Albert W., Roof, Robin L., Rafferty, Michael F., Kostlan, Catherine R., Scholten, Jeffrey D., Hood, Molly, Ren, Xiao-Dan, Schielke, Gerald P., Su, Ti-Zhi, Taylor, Charles P., Mistry, Anil, McConnell, Patrick, Hasemann, Charles, Ohren, Jeffrey
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
Published in Bioorganic & medicinal chemistry letters (01.05.2006)
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A specific inhibitor of calcium/calmodulin-dependent protein kinase-II provides neuroprotection against NMDA- and hypoxia/hypoglycemia-induced cell death
Hajimohammadreza, I, Probert, AW, Coughenour, LL, Borosky, SA, Marcoux, FW, Boxer, PA, Wang, KK
Published in The Journal of neuroscience (01.05.1995)
Published in The Journal of neuroscience (01.05.1995)
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Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells: Volume 274, Number 1 (2000), pages 16–21
Nath, Rathna, Davis, Megan, Probert, Albert W., Kupina, Nancy C., Ren, Xiaodong, Schielke, Gerald P., Wang, Kevin K.W.
Published in Biochemical and biophysical research communications (16.09.2000)
Published in Biochemical and biophysical research communications (16.09.2000)
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Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells
Nath, Rathna, Davis, Megan, Probert, Albert W., Kupina, Nancy C., Ren, Xiaodong, Schielke, Gerald P., Wang, Kevin K.W.
Published in Biochemical and biophysical research communications (16.09.2000)
Published in Biochemical and biophysical research communications (16.09.2000)
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Alpha-mercaptoacrylic acid derivatives as novel selective calpain inhibitors
Wang, K K, Posner, A, Raser, K J, Buroker-Kilgore, M, Nath, R, Hajimohammadreza, I, Probert, A W, Marcoux, F W, Lunney, E A, Hays, S J, Yuen P-W
Published in Advances in experimental medicine and biology (1996)
Published in Advances in experimental medicine and biology (1996)
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Treatment with conotoxin, an 'N-type' calcium channel blocker, in neuronal hypoxic-ischemic injury
Madden, K P, Clark, W M, Marcoux, F W, Probert, Jr, A W, Weber, M L, Rivier, J, Zivin, J A
Published in Brain research (24.12.1990)
Published in Brain research (24.12.1990)
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