A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing
Vizoso, Miguel, E. J. Pritchard, Colin, Bombardelli, Lorenzo, van den Broek, Bram, Krimpenfort, Paul, Beijersbergen, Roderick L., Jalink, Kees, van Rheenen, Jacco
Published in Nature communications (28.10.2022)
Published in Nature communications (28.10.2022)
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A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype
Shah, Ronak, van den Berk, Paul C M, Pritchard, Colin E J, Song, Ji-Ying, Kreft, Maaike, Pilzecker, Bas, Jacobs, Heinz
Published in International journal of molecular sciences (01.07.2023)
Published in International journal of molecular sciences (01.07.2023)
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Towards an understanding of C9orf82 protein/CAAP1 function
Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Pritchard, Colin E J, Song, Ji-Ying, Muhaimin, Fitriari Izzatunnisa, Wijdeven, Ruud H, Huijbers, Ivo J, Neefjes, Jacques, Jacobs, Heinz
Published in PloS one (10.01.2019)
Published in PloS one (10.01.2019)
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Inhibition of carnitine palmitoyl-transferase 1 is a potential target in a mouse model of Parkinson’s disease
Trabjerg, Michael Sloth, Andersen, Dennis Christian, Huntjens, Pam, Mørk, Kasper, Warming, Nikolaj, Kullab, Ulla Bismark, Skjønnemand, Marie-Louise Nibelius, Oklinski, Michal Krystian, Oklinski, Kirsten Egelund, Bolther, Luise, Kroese, Lona J., Pritchard, Colin E. J., Huijbers, Ivo J., Corthals, Angelique, Søndergaard, Mads Toft, Kjeldal, Henrik Bech, Pedersen, Cecilie Fjord Morre, Nieland, John Dirk Vestergaard
Published in NPJ Parkinson's Disease (21.01.2023)
Published in NPJ Parkinson's Disease (21.01.2023)
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Direct Generation of Conditional Alleles Using CRISPR/Cas9 in Mouse Zygotes
Pritchard, Colin E J, Kroese, Lona J, Huijbers, Ivo J
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2017)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2017)
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A mouse model that is immunologically tolerant to reporter and modifier proteins
Bresser, Kaspar, Dijkgraaf, Feline E., Pritchard, Colin E. J., Huijbers, Ivo J., Song, Ji-Ying, Rohr, Jan C., Scheeren, Ferenc A., Schumacher, Ton N.
Published in Communications biology (29.05.2020)
Published in Communications biology (29.05.2020)
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TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development
Cornelissen, Lisette M, Drenth, Anne Paulien, van der Burg, Eline, de Bruijn, Roebi, Pritchard, Colin E J, Huijbers, Ivo J, Zwart, Wilbert, Jonkers, Jos
Published in Genes & development (01.02.2020)
Published in Genes & development (01.02.2020)
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A Lamb1Dendra2 mouse model identifies basement-membrane-producing origins and dynamics in PyMT breast tumors
Morgner, Jessica, Bornes, Laura, Hahn, Kerstin, López-Iglesias, Carmen, Kroese, Lona, Pritchard, Colin E.J., Vennin, Claire, Peters, Peter J., Huijbers, Ivo, van Rheenen, Jacco
Published in Developmental cell (10.04.2023)
Published in Developmental cell (10.04.2023)
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Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL
Antoszewski, Mateusz, Fournier, Nadine, Ruiz Buendía, Gustavo A., Lourenco, Joao, Liu, Yuanlong, Sugrue, Tara, Dubey, Christelle, Nkosi, Marianne, Pritchard, Colin E.J., Huijbers, Ivo J., Segat, Gabriela C., Alonso-Moreno, Sandra, Serracanta, Elisabeth, Belver, Laura, Ferrando, Adolfo A., Ciriello, Giovanni, Weng, Andrew P., Koch, Ute, Radtke, Freddy
Published in Blood (21.04.2022)
Published in Blood (21.04.2022)
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Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division
Maia, Ana Rita R., Linder, Simon, Song, Ji-Ying, Vaarting, Chantal, Boon, Ute, Pritchard, Colin E. J., Velds, Arno, Huijbers, Ivo J., van Tellingen, Olaf, Jonkers, Jos, Medema, René H.
Published in British journal of cancer (01.06.2018)
Published in British journal of cancer (01.06.2018)
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Mammalian life depends on two distinct pathways of DNA damage tolerance
Buoninfante, Olimpia Alessandra, Pilzecker, Bas, Spanjaard, Aldo, de Groot, Daniël, Prekovic, Stefan, Song, Ji-Ying, Lieftink, Cor, Ayidah, Matilda, Pritchard, Colin E J, Vivié, Judith, Mcgrath, Kathleen E, Huijbers, Ivo J, Philipsen, Sjaak, von Lindern, Marieke, Zwart, Wilbert, Beijersbergen, Roderick L, Palis, James, van den Berk, Paul C M, Jacobs, Heinz
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (24.01.2023)
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A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair
Pulver, Emilia M, Mukherjee, Chirantani, van de Kamp, Gerarda, Roobol, Stefan J, Rother, Magdalena B, van der Gulden, Hanneke, de Bruijn, Roebi, Lattanzio, Maria Valeria, van der Burg, Eline, Drenth, Anne Paulien, Verkaik, Nicole S, Hahn, Kerstin, Klarenbeek, Sjoerd, de Korte-Grimmerink, Renske, van de Ven, Marieke, Pritchard, Colin E J, Huijbers, Ivo J, Xia, Bing, van Gent, Dik C, Essers, Jeroen, van Attikum, Haico, Ray Chaudhuri, Arnab, Bouwman, Peter, Jonkers, Jos
Published in Cancer research (Chicago, Ill.) (15.12.2021)
Published in Cancer research (Chicago, Ill.) (15.12.2021)
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The Ig heavy chain protein but not its message controls early B cell development
Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Hao, Bingtao, Krijger, Peter H. L., Pritchard, Colin E. J., de Rink, Iris, Muhaimin, Fitriari Izzatunnisa, Nurzijah, Ika, van Baalen, Martijn, Kerkhoven, Ron M., van den Berk, Paul C. M., Skok, Jane A., Jacobs, Heinz
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2020)
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Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair
Shah, Ronak, Aslam, Muhammad Assad, Spanjaard, Aldo, de Groot, Daniel, Zürcher, Lisa M, Altelaar, Maarten, Hoekman, Liesbeth, Pritchard, Colin E J, Pilzecker, Bas, van den Berk, Paul C M, Jacobs, Heinz
Published in PNAS nexus (01.07.2024)
Published in PNAS nexus (01.07.2024)
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Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy
Widmer, Carmen A, Klebic, Ismar, Domanitskaya, Natalya, Decollogny, Morgane, Howald, Denise, Siffert, Myriam, Essers, Paul, Nowicka, Zuzanna, Stokar-Regenscheit, Nadine, van de Ven, Marieke, de Korte-Grimmerink, Renske, Galván, José A, Pritchard, Colin E J, Huijbers, Ivo J, Fendler, Wojciech, Vens, Conchita, Rottenberg, Sven
Published in Cancer research communications (26.10.2022)
Published in Cancer research communications (26.10.2022)
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CREB Binding Protein Interacts with Nucleoporin-Specific FG Repeats That Activate Transcription and Mediate NUP98-HOXA9 Oncogenicity
Kasper, Lawryn H., Brindle, Paul K., Schnabel, Catherine A., Pritchard, Colin E. J., Cleary, Michael L., van Deursen, Jan M. A.
Published in Molecular and Cellular Biology (01.01.1999)
Published in Molecular and Cellular Biology (01.01.1999)
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