Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations
Prins, Bram P., Kuchenbaecker, Karoline B., Bao, Yanchun, Smart, Melissa, Zabaneh, Delilah, Fatemifar, Ghazaleh, Luan, Jian’an, Wareham, Nick J., Scott, Robert A., Perry, John R. B., Langenberg, Claudia, Benzeval, Michaela, Kumari, Meena, Zeggini, Eleftheria
Published in Scientific reports (08.09.2017)
Published in Scientific reports (08.09.2017)
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Journal Article
Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age
Harris, Sarah E., Cox, Simon R., Bell, Steven, Marioni, Riccardo E., Prins, Bram P., Pattie, Alison, Corley, Janie, Muñoz Maniega, Susana, Valdés Hernández, Maria, Morris, Zoe, John, Sally, Bronson, Paola G., Tucker-Drob, Elliot M., Starr, John M., Bastin, Mark E., Wardlaw, Joanna M., Butterworth, Adam S., Deary, Ian J.
Published in Nature communications (10.02.2020)
Published in Nature communications (10.02.2020)
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Journal Article
Genomic atlas of the human plasma proteome
Sun, Benjamin B., Maranville, Joseph C., Peters, James E., Stacey, David, Staley, James R., Blackshaw, James, Burgess, Stephen, Jiang, Tao, Paige, Ellie, Surendran, Praveen, Oliver-Williams, Clare, Kamat, Mihir A., Prins, Bram P., Wilcox, Sheri K., Zimmerman, Erik S., Chi, An, Bansal, Narinder, Spain, Sarah L., Wood, Angela M., Morrell, Nicholas W., Bradley, John R., Janjic, Nebojsa, Roberts, David J., Ouwehand, Willem H., Todd, John A., Soranzo, Nicole, Suhre, Karsten, Paul, Dirk S., Fox, Caroline S., Plenge, Robert M., Danesh, John, Runz, Heiko, Butterworth, Adam S.
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Journal Article
Genetics of coronary artery disease: Genome-wide association studies and beyond
Prins, Bram P, Lagou, Vasiliki, Asselbergs, Folkert W, Snieder, Harold, Fu, Jingyuan
Published in Atherosclerosis (01.11.2012)
Published in Atherosclerosis (01.11.2012)
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Journal Article
Trans‐ethnic genomic informed risk assessment for Alzheimer's disease: An International Hundred K+ Cohorts Consortium study
Sleiman, Patrick M., Qu, Hui‐Qi, Connolly, John J., Mentch, Frank, Pereira, Alexandre, Lotufo, Paulo A., Tollman, Stephen, Choudhury, Ananyo, Ramsay, Michele, Kato, Norihiro, Ozaki, Kouichi, Mitsumori, Risa, Jeon, Jae‐Pil, Hong, Chang Hyung, Son, Sang Joon, Roh, Hyun Woong, Lee, Dong‐gi, Mukadam, Naaheed, Foote, Isabelle F., Marshall, Charles R., Butterworth, Adam, Prins, Bram P., Glessner, Joseph T., Hakonarson, Hakon
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Eosinophil Count Is a Common Factor for Complex Metabolic and Pulmonary Traits and Diseases: The LifeLines Cohort Study
Amini, Marzyeh, Bashirova, Dinara, Prins, Bram P, Corpeleijn, Eva, Bruinenberg, Marcel, Franke, Lude, Harst, Pim van der, Navis, Gerjan, Wolffenbuttel, Bruce H R, Stolk, Ronald P, Wijmenga, Cisca, Postma, Dirkje S, Koppelman, Gerard H, Boezen, H Marike, Vonk, Judith, Snieder, Harold, Alizadeh, Behrooz Z
Published in PloS one (15.12.2016)
Published in PloS one (15.12.2016)
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Journal Article
lodGWAS: a software package for genome-wide association analysis of biomarkers with a limit of detection
Vaez, Ahmad, van der Most, Peter J, Prins, Bram P, Snieder, Harold, van den Heuvel, Edwin, Alizadeh, Behrooz Z, Nolte, Ilja M
Published in Bioinformatics (15.05.2016)
Published in Bioinformatics (15.05.2016)
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Journal Article
Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study
Amini, Marzyeh, Vonk, Judith M., Abbasi, Ali, Prins, Bram P., Bruinenberg, Marcel, Franke, Lude, van der Harst, Pim, Navis, Gerjan, Koppelman, Gerard H., Wolffenbuttel, Bruce H. R., Boezen, H. Marike, Snieder, Harold, Chasman, Daniel I., Alizadeh, Behrooz Z.
Published in Twin research and human genetics (01.04.2018)
Published in Twin research and human genetics (01.04.2018)
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Journal Article
In Silico Post Genome-Wide Association Studies Analysis of C-Reactive Protein Loci Suggests an Important Role for Interferons
Vaez, Ahmad, Jansen, Rick, Prins, Bram P, Hottenga, Jouke-Jan, de Geus, Eco J C, Boomsma, Dorret I, Penninx, Brenda W J H, Nolte, Ilja M, Snieder, Harold, Alizadeh, Behrooz Z
Published in Circulation. Cardiovascular genetics (01.06.2015)
Published in Circulation. Cardiovascular genetics (01.06.2015)
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Journal Article
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19
Gaziano, Liam, Giambartolomei, Claudia, Pereira, Alexandre C., Gaulton, Anna, Posner, Daniel C., Swanson, Sonja A., Ho, Yuk-Lam, Iyengar, Sudha K., Kosik, Nicole M., Vujkovic, Marijana, Gagnon, David R., Bento, A. Patrícia, Barrio-Hernandez, Inigo, Rönnblom, Lars, Hagberg, Niklas, Lundtoft, Christian, Langenberg, Claudia, Pietzner, Maik, Valentine, Dennis, Gustincich, Stefano, Tartaglia, Gian Gaetano, Allara, Elias, Surendran, Praveen, Burgess, Stephen, Zhao, Jing Hua, Peters, James E., Prins, Bram P., Angelantonio, Emanuele Di, Devineni, Poornima, Shi, Yunling, Lynch, Kristine E., DuVall, Scott L., Garcon, Helene, Thomann, Lauren O., Zhou, Jin J., Gorman, Bryan R., Huffman, Jennifer E., O’Donnell, Christopher J., Tsao, Philip S., Beckham, Jean C., Pyarajan, Saiju, Muralidhar, Sumitra, Huang, Grant D., Ramoni, Rachel, Beltrao, Pedro, Danesh, John, Hung, Adriana M., Chang, Kyong-Mi, Sun, Yan V., Joseph, Jacob, Leach, Andrew R., Edwards, Todd L., Cho, Kelly, Gaziano, J. Michael, Butterworth, Adam S., Casas, Juan P.
Published in Nature medicine (01.04.2021)
Published in Nature medicine (01.04.2021)
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Journal Article
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study
Prins, Bram P, Abbasi, Ali, Wong, Anson, Vaez, Ahmad, Nolte, Ilja, Franceschini, Nora, Stuart, Philip E, Guterriez Achury, Javier, Mistry, Vanisha, Bradfield, Jonathan P, Valdes, Ana M, Bras, Jose, Shatunov, Aleksey, Lu, Chen, Han, Buhm, Raychaudhuri, Soumya, Bevan, Steve, Mayes, Maureen D, Tsoi, Lam C, Evangelou, Evangelos, Nair, Rajan P, Grant, Struan F A, Polychronakos, Constantin, Radstake, Timothy R D, van Heel, David A, Dunstan, Melanie L, Wood, Nicholas W, Al-Chalabi, Ammar, Dehghan, Abbas, Hakonarson, Hakon, Markus, Hugh S, Elder, James T, Knight, Jo, Arking, Dan E, Spector, Timothy D, Koeleman, Bobby P C, van Duijn, Cornelia M, Martin, Javier, Morris, Andrew P, Weersma, Rinse K, Wijmenga, Cisca, Munroe, Patricia B, Perry, John R B, Pouget, Jennie G, Jamshidi, Yalda, Snieder, Harold, Alizadeh, Behrooz Z
Published in PLoS medicine (21.06.2016)
Published in PLoS medicine (21.06.2016)
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Journal Article
Rare variant associations with plasma protein levels in the UK Biobank
Dhindsa, Ryan S., Burren, Oliver S., Sun, Benjamin B., Prins, Bram P., Matelska, Dorota, Wheeler, Eleanor, Mitchell, Jonathan, Oerton, Erin, Hristova, Ventzislava A., Smith, Katherine R., Carss, Keren, Wasilewski, Sebastian, Harper, Andrew R., Paul, Dirk S., Fabre, Margarete A., Runz, Heiko, Viollet, Coralie, Challis, Benjamin, Platt, Adam, Vitsios, Dimitrios, Ashley, Euan A., Whelan, Christopher D., Pangalos, Menelas N., Wang, Quanli, Petrovski, Slavé
Published in Nature (London) (12.10.2023)
Published in Nature (London) (12.10.2023)
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Journal Article
Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study
Behr, Elijah R, Savio-Galimberti, Eleonora, Barc, Julien, Holst, Anders G, Petropoulou, Evmorfia, Prins, Bram P, Jabbari, Javad, Torchio, Margherita, Berthet, Myriam, Mizusawa, Yuka, Yang, Tao, Nannenberg, Eline A, Dagradi, Federica, Weeke, Peter, Bastiaenan, Rachel, Ackerman, Michael J, Haunso, Stig, Leenhardt, Antoine, Kääb, Stefan, Probst, Vincent, Redon, Richard, Sharma, Sanjay, Wilde, Arthur, Tfelt-Hansen, Jacob, Schwartz, Peter, Roden, Dan M, Bezzina, Connie R, Olesen, Morten, Darbar, Dawood, Guicheney, Pascale, Crotti, Lia, Jamshidi, Yalda
Published in Cardiovascular research (01.06.2015)
Published in Cardiovascular research (01.06.2015)
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Journal Article
Evidence for large-scale gene-by-smoking interaction effects on pulmonary function
Aschard, Hugues, Tobin, Martin D, Hancock, Dana B, Skurnik, David, Sood, Akshay, James, Alan, Vernon Smith, Albert, Manichaikul, Ani W, Campbell, Archie, Prins, Bram P, Hayward, Caroline, Loth, Daan W, Porteous, David J, Strachan, David P, Zeggini, Eleftheria, O'Connor, George T, Brusselle, Guy G, Boezen, H Marike, Schulz, Holger, Deary, Ian J, Hall, Ian P, Rudan, Igor, Kaprio, Jaakko, Wilson, James F, Wilk, Jemma B, Huffman, Jennifer E, Hua Zhao, Jing, de Jong, Kim, Lyytikäinen, Leo-Pekka, Wain, Louise V, Jarvelin, Marjo-Riitta, Kähönen, Mika, Fornage, Myriam, Polasek, Ozren, Cassano, Patricia A, Barr, R Graham, Rawal, Rajesh, Harris, Sarah E, Gharib, Sina A, Enroth, Stefan, Heckbert, Susan R, Lehtimäki, Terho, Gyllensten, Ulf, Jackson, Victoria E, Gudnason, Vilmundur, Tang, Wenbo, Dupuis, Josée, Soler Artigas, María, Joshi, Amit D, London, Stephanie J, Kraft, Peter
Published in International journal of epidemiology (01.06.2017)
Published in International journal of epidemiology (01.06.2017)
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Journal Article
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19
Gaziano, Liam, Giambartolomei, Claudia, Pereira, Alexandre C., Gaulton, Anna, Posner, Daniel C., Swanson, Sonja A., Ho, Yuk-Lam, Iyengar, Sudha K., Kosik, Nicole M., Vujkovic, Marijana, Gagnon, David R., Bento, A. Patrícia, Barrio-Hernandez, Inigo, Rönnblom, Lars, Hagberg, Niklas, Lundtoft, Christian, Langenberg, Claudia, Pietzner, Maik, Valentine, Dennis, Gustincich, Stefano, Tartaglia, Gian Gaetano, Allara, Elias, Surendran, Praveen, Burgess, Stephen, Zhao, Jing Hua, Peters, James E., Prins, Bram P., Angelantonio, Emanuele Di, Devineni, Poornima, Shi, Yunling, Lynch, Kristine E., DuVall, Scott L., Garcon, Helene, Thomann, Lauren O., Zhou, Jin J., Gorman, Bryan R., Huffman, Jennifer E., O’Donnell, Christopher J., Tsao, Philip S., Beckham, Jean C., Pyarajan, Saiju, Muralidhar, Sumitra, Huang, Grant D., Ramoni, Rachel, Beltrao, Pedro, Danesh, John, Hung, Adriana M., Chang, Kyong-Mi, Sun, Yan V., Joseph, Jacob, Leach, Andrew R., Edwards, Todd L., Cho, Kelly, Gaziano, J. Michael, Butterworth, Adam S., Casas, Juan P.
Published in Nature medicine (01.04.2021)
Published in Nature medicine (01.04.2021)
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Journal Article
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals
Bihlmeyer, Nathan A, Brody, Jennifer A, Smith, Albert Vernon, Warren, Helen R, Lin, Honghuang, Isaacs, Aaron, Liu, Ching-Ti, Marten, Jonathan, Radmanesh, Farid, Hall, Leanne M, Grarup, Niels, Mei, Hao, Müller-Nurasyid, Martina, Huffman, Jennifer E, Verweij, Niek, Guo, Xiuqing, Yao, Jie, Li-Gao, Ruifang, van den Berg, Marten, Weiss, Stefan, Prins, Bram P, van Setten, Jessica, Haessler, Jeffrey, Lyytikäinen, Leo-Pekka, Li, Man, Alonso, Alvaro, Soliman, Elsayed Z, Bis, Joshua C, Austin, Tom, Chen, Yii-Der Ida, Psaty, Bruce M, Harrris, Tamara B, Launer, Lenore J, Padmanabhan, Sandosh, Dominiczak, Anna, Huang, Paul L, Xie, Zhijun, Ellinor, Patrick T, Kors, Jan A, Campbell, Archie, Murray, Alison D, Nelson, Christopher P, Tobin, Martin D, Bork-Jensen, Jette, Hansen, Torben, Pedersen, Oluf, Linneberg, Allan, Sinner, Moritz F, Peters, Annette, Waldenberger, Melanie, Meitinger, Thomas, Perz, Siegfried, Kolcic, Ivana, Rudan, Igor, de Boer, Rudolf A, van der Meer, Peter, Lin, Henry J, Taylor, Kent D, de Mutsert, Renée, Trompet, Stella, Jukema, J Wouter, Maan, Arie C, Stricker, Bruno H C, Rivadeneira, Fernando, Uitterlinden, André, Völker, Uwe, Homuth, Georg, Völzke, Henry, Felix, Stephan B, Mangino, Massimo, Spector, Timothy D, Bots, Michiel L, Perez, Marco, Raitakari, Olli T, Kähönen, Mika, Mononen, Nina, Gudnason, Vilmundur, Munroe, Patricia B, Lubitz, Steven A, van Duijn, Cornelia M, Newton-Cheh, Christopher H, Hayward, Caroline, Rosand, Jonathan, Samani, Nilesh J, Kanters, Jørgen K, Wilson, James G, Kääb, Stefan, Polasek, Ozren, van der Harst, Pim, Heckbert, Susan R, Rotter, Jerome I, Mook-Kanamori, Dennis O, Eijgelsheim, Mark, Dörr, Marcus, Jamshidi, Yalda, Asselbergs, Folkert W, Kooperberg, Charles, Lehtimäki, Terho, Arking, Dan E, Sotoodehnia, Nona
Published in Circulation. Cardiovascular genetics (01.01.2018)
Published in Circulation. Cardiovascular genetics (01.01.2018)
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Journal Article
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval
Lin, Honghuang, van Setten, Jessica, Smith, Albert V, Bihlmeyer, Nathan A, Warren, Helen R, Brody, Jennifer A, Radmanesh, Farid, Hall, Leanne, Grarup, Niels, Müller-Nurasyid, Martina, Boutin, Thibaud, Verweij, Niek, Lin, Henry J, Li-Gao, Ruifang, van den Berg, Marten E, Marten, Jonathan, Weiss, Stefan, Prins, Bram P, Haessler, Jeffrey, Lyytikäinen, Leo-Pekka, Mei, Hao, Harris, Tamara B, Launer, Lenore J, Li, Man, Alonso, Alvaro, Soliman, Elsayed Z, Connell, John M, Huang, Paul L, Weng, Lu-Chen, Jameson, Heather S, Hucker, William, Hanley, Alan, Tucker, Nathan R, Chen, Yii-Der Ida, Bis, Joshua C, Rice, Kenneth M, Sitlani, Colleen M, Kors, Jan A, Xie, Zhijun, Wen, Chengping, Magnani, Jared W, Nelson, Christopher P, Kanters, Jørgen K, Sinner, Moritz F, Strauch, Konstantin, Peters, Annette, Waldenberger, Melanie, Meitinger, Thomas, Bork-Jensen, Jette, Pedersen, Oluf, Linneberg, Allan, Rudan, Igor, de Boer, Rudolf A, van der Meer, Peter, Yao, Jie, Guo, Xiuqing, Taylor, Kent D, Sotoodehnia, Nona, Rotter, Jerome I, Mook-Kanamori, Dennis O, Trompet, Stella, Rivadeneira, Fernando, Uitterlinden, André, Eijgelsheim, Mark, Padmanabhan, Sandosh, Smith, Blair H, Völzke, Henry, Felix, Stephan B, Homuth, Georg, Völker, Uwe, Mangino, Massimo, Spector, Timothy D, Bots, Michiel L, Perez, Marco, Kähönen, Mika, Raitakari, Olli T, Gudnason, Vilmundur, Arking, Dan E, Munroe, Patricia B, Psaty, Bruce M, van Duijn, Cornelia M, Benjamin, Emelia J, Rosand, Jonathan, Samani, Nilesh J, Hansen, Torben, Kääb, Stefan, Polasek, Ozren, van der Harst, Pim, Heckbert, Susan R, Jukema, J Wouter, Stricker, Bruno H, Hayward, Caroline, Dörr, Marcus, Jamshidi, Yalda, Asselbergs, Folkert W, Kooperberg, Charles, Lehtimäki, Terho, Wilson, James G, Ellinor, Patrick T, Lubitz, Steven A
Published in Circulation. Cardiovascular genetics (01.05.2018)
Published in Circulation. Cardiovascular genetics (01.05.2018)
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Journal Article
Neurology-related protein biomarkers are associated with general fluid cognitive ability and brain volume in older age
Harris, Sarah E, Cox, Simon R, Bell, Steven, Marioni, Riccardo E, Prins, Bram P, Pattie, Alison, Corley, Janie, Susanna Munoz Maniega, Maria Valdes Hernandez, Morris, Zoe, John, Sally, Bronson, Paola G, Tucker-Drob, Elliot M, Starr, John M, Bastin, Mark E, Wardlaw, Joanna M, Butterworth, Adam S, Deary, Ian J
Published in bioRxiv (04.07.2019)
Published in bioRxiv (04.07.2019)
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