Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix
Cochemé, Helena M., Quin, Caroline, McQuaker, Stephen J., Cabreiro, Filipe, Logan, Angela, Prime, Tracy A., Abakumova, Irina, Patel, Jigna V., Fearnley, Ian M., James, Andrew M., Porteous, Carolyn M., Smith, Robin A.J., Saeed, Saima, Carré, Jane E., Singer, Mervyn, Gems, David, Hartley, Richard C., Partridge, Linda, Murphy, Michael P.
Published in Cell metabolism (02.03.2011)
Published in Cell metabolism (02.03.2011)
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Journal Article
A sensitive mass spectrometric assay for mitochondrial CoQ pool redox state in vivo
Burger, Nils, Logan, Angela, Prime, Tracy A., Mottahedin, Amin, Caldwell, Stuart T., Krieg, Thomas, Hartley, Richard C., James, Andrew M., Murphy, Michael P.
Published in Free radical biology & medicine (01.02.2020)
Published in Free radical biology & medicine (01.02.2020)
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Journal Article
Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat
Robb, Ellen L., Gawel, Justyna M., Aksentijević, Dunja, Cochemé, Helena M., Stewart, Tessa S., Shchepinova, Maria M., Qiang, He, Prime, Tracy A., Bright, Thomas P., James, Andrew M., Shattock, Michael J., Senn, Hans M., Hartley, Richard C., Murphy, Michael P.
Published in Free radical biology & medicine (01.12.2015)
Published in Free radical biology & medicine (01.12.2015)
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Journal Article
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/–/ApoE–/– mice
Mercer, John R., Yu, Emma, Figg, Nichola, Cheng, Kian-Kai, Prime, Tracy A., Griffin, Julian L., Masoodi, Mojgan, Vidal-Puig, Antonio, Murphy, Michael P., Bennett, Martin R.
Published in Free radical biology & medicine (01.03.2012)
Published in Free radical biology & medicine (01.03.2012)
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Journal Article
MitoNeoD: A Mitochondria-Targeted Superoxide Probe
Shchepinova, Maria M., Cairns, Andrew G., Prime, Tracy A., Logan, Angela, James, Andrew M., Hall, Andrew R., Vidoni, Sara, Arndt, Sabine, Caldwell, Stuart T., Prag, Hiran A., Pell, Victoria R., Krieg, Thomas, Mulvey, John F., Yadav, Pooja, Cobley, James N., Bright, Thomas P., Senn, Hans M., Anderson, Robert F., Murphy, Michael P., Hartley, Richard C.
Published in Cell chemical biology (19.10.2017)
Published in Cell chemical biology (19.10.2017)
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Journal Article
The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease
Solesio, María E, Prime, Tracy A, Logan, Angela, Murphy, Michael P, Del Mar Arroyo-Jimenez, María, Jordán, Joaquín, Galindo, María F
Published in Biochimica et biophysica acta (01.01.2013)
Published in Biochimica et biophysica acta (01.01.2013)
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Journal Article
Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry
Logan, Angela, Pell, Victoria R., Shaffer, Karl J., Evans, Cameron, Stanley, Nathan J., Robb, Ellen L., Prime, Tracy A., Chouchani, Edward T., Cochemé, Helena M., Fearnley, Ian M., Vidoni, Sara, James, Andrew M., Porteous, Carolyn M., Partridge, Linda, Krieg, Thomas, Smith, Robin A.J., Murphy, Michael P.
Published in Cell metabolism (09.02.2016)
Published in Cell metabolism (09.02.2016)
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Journal Article
The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model
Dare, Anna J., MBBCh, PhD, Logan, Angela, PhD, Prime, Tracy A., BSc, Rogatti, Sebastian, BSc, Goddard, Martin, MBBCh, FRCPath, Bolton, Eleanor M., PhD, Bradley, J. Andrew, MBBCh, PhD, FRCS, Pettigrew, Gavin J., MBBCh, MD, FRCS, Murphy, Michael P., PhD, Saeb-Parsy, Kourosh, MBBCh, PhD, FRCS
Published in The Journal of heart and lung transplantation (01.11.2015)
Published in The Journal of heart and lung transplantation (01.11.2015)
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Journal Article
Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo
Booty, Lee M, Gawel, Justyna M, Cvetko, Filip, Caldwell, Stuart T, Hall, Andrew R, Mulvey, John F, James, Andrew M, Hinchy, Elizabeth C, Prime, Tracy A, Arndt, Sabine, Beninca, Cristiane, Bright, Thomas P, Clatworthy, Menna R, Ferdinand, John R, Prag, Hiran A, Logan, Angela, Prudent, Julien, Krieg, Thomas, Hartley, Richard C, Murphy, Michael P
Published in Cell chemical biology (21.03.2019)
Published in Cell chemical biology (21.03.2019)
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Journal Article
Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells
Ross, Meredith F, Prime, Tracy A, Abakumova, Irina, James, Andrew M, Porteous, Carolyn M, Smith, Robin A J, Murphy, Michael P
Published in Biochemical journal (01.05.2008)
Published in Biochemical journal (01.05.2008)
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Journal Article
Selective Uncoupling of Individual Mitochondria within a Cell Using a Mitochondria-Targeted Photoactivated Protonophore
Chalmers, Susan, Caldwell, Stuart T, Quin, Caroline, Prime, Tracy A, James, Andrew M, Cairns, Andrew G, Murphy, Michael P, McCarron, John G, Hartley, Richard C
Published in Journal of the American Chemical Society (18.01.2012)
Published in Journal of the American Chemical Society (18.01.2012)
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Journal Article
Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA
Arndt, Sabine, Baeza-Garza, Carlos D., Logan, Angela, Rosa, Tiziana, Wedmann, Rudolf, Prime, Tracy A., Martin, Jack L., Saeb-Parsy, Kourosh, Krieg, Thomas, Filipovic, Milos R., Hartley, Richard C., Murphy, Michael P.
Published in The Journal of biological chemistry (12.05.2017)
Published in The Journal of biological chemistry (12.05.2017)
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Journal Article
A mitochondria-targeted derivative of ascorbate: MitoC
Finichiu, Peter G., Larsen, David S., Evans, Cameron, Larsen, Lesley, Bright, Thomas P., Robb, Ellen L., Trnka, Jan, Prime, Tracy A., James, Andrew M., Smith, Robin A.J., Murphy, Michael P.
Published in Free radical biology & medicine (01.12.2015)
Published in Free radical biology & medicine (01.12.2015)
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Journal Article
Corrigendum to “A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding” [Redox Biol. 72 (2024) 103161]
Sorby-Adams, Annabel, Prime, Tracy A., Miljkovic, Jan Lj, Prag, Hiran A., Krieg, Thomas, Murphy, Michael P.
Published in Redox biology (01.08.2024)
Published in Redox biology (01.08.2024)
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Journal Article
A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding
Sorby-Adams, Annabel, Prime, Tracy A., Miljkovic, Jan Lj, Prag, Hiran A., Krieg, Thomas, Murphy, Michael P.
Published in Redox biology (01.06.2024)
Published in Redox biology (01.06.2024)
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Journal Article
mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury
Prime, Tracy A, Blaikie, Frances H, Evans, Cameron, Nadtochiy, Sergiy M, James, Andrew M, Dahm, Christina C, Vitturi, Dario A, Patel, Rakesh P, Hiley, C. Robin, Abakumova, Irina, Requejo, Raquel, Chouchani, Edward T, Hurd, Thomas R, Garvey, John F, Taylor, Cormac T, Brookes, Paul S, Smith, Robin A.J, Murphy, Michael P
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2009)
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Journal Article
Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila
Cochemé, Helena M, Logan, Angela, Prime, Tracy A, Abakumova, Irina, Quin, Caroline, McQuaker, Stephen J, Patel, Jigna V, Fearnley, Ian M, James, Andrew M, Porteous, Carolyn M, Smith, Robin A J, Hartley, Richard C, Partridge, Linda, Murphy, Michael P
Published in Nature protocols (19.04.2012)
Published in Nature protocols (19.04.2012)
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Journal Article
Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury
Miljkovic, Jan Lj, Burger, Nils, Gawel, Justyna M., Mulvey, John F., Norman, Abigail A.I., Nishimura, Takanori, Tsujihata, Yoshiyuki, Logan, Angela, Sauchanka, Olga, Caldwell, Stuart T., Morris, Jordan L., Prime, Tracy A., Warrington, Stefan, Prudent, Julien, Bates, Georgina R., Aksentijević, Dunja, Prag, Hiran A., James, Andrew M., Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Published in Redox biology (01.09.2022)
Published in Redox biology (01.09.2022)
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Journal Article
A ratiometric fluorescent probe for assessing mitochondrial phospholipid peroxidation within living cells
Prime, Tracy A., Forkink, Marleen, Logan, Angela, Finichiu, Peter G., McLachlan, Jennifer, Li Pun, Pamela Boon, Koopman, Werner J.H., Larsen, Lesley, Latter, Melissa J., Smith, Robin A.J., Murphy, Michael P.
Published in Free radical biology & medicine (01.08.2012)
Published in Free radical biology & medicine (01.08.2012)
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Journal Article
A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes
Pun, Pamela Boon Li, Logan, Angela, Darley-Usmar, Victor, Chacko, Balu, Johnson, Michelle S., Huang, Guang W., Rogatti, Sebastian, Prime, Tracy A., Methner, Carmen, Krieg, Thomas, Fearnley, Ian M., Larsen, Lesley, Larsen, David S., Menger, Katja E., Collins, Yvonne, James, Andrew M., Kumar, G.D. Kishore, Hartley, Richard C., Smith, Robin A.J., Murphy, Michael P.
Published in Free radical biology & medicine (01.02.2014)
Published in Free radical biology & medicine (01.02.2014)
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Journal Article