Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy
Koedoot, Esmee, Wolters, Liesanne, Smid, Marcel, Stoilov, Peter, Burger, Gerhard A., Herpers, Bram, Yan, Kuan, Price, Leo S., Martens, John W. M., Le Dévédec, Sylvia E., van de Water, Bob
Published in Scientific reports (31.03.2021)
Published in Scientific reports (31.03.2021)
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3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors
Badder, Luned M, Hollins, Andrew J, Herpers, Bram, Yan, Kuan, Ewan, Kenneth B, Thomas, Mairian, Shone, Jennifer R, Badder, Delyth A, Naven, Marc, Ashelford, Kevin E, Hargest, Rachel, Clarke, Alan R, Esdar, Christina, Buchstaller, Hans-Peter, Treherne, J. Mark, Boj, Sylvia, Ramezanpour, Bahar, Wienke, Dirk, Price, Leo S, Shaw, Paul H, Dale, Trevor C
Published in PloS one (18.08.2020)
Published in PloS one (18.08.2020)
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Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues
Di, Zi, Klop, Maarten J D, Rogkoti, Vasiliki-Maria, Le Dévédec, Sylvia E, van de Water, Bob, Verbeek, Fons J, Price, Leo S, Meerman, John H N
Published in PloS one (07.10.2014)
Published in PloS one (07.10.2014)
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Epac-Rap Signaling Reduces Oxidative Stress in the Tubular Epithelium
STOKMAN, Geurt, YU QIN, VAN DE WATER, Bob, KOK, Robbert J, PRICE, Leo S, BOOIJ, Tijmen H, RAMAIAHGARI, Sreenivasa, LACOMBE, Marie, DOLMAN, M. Emmy M, VAN DORENMALEN, Kim M. A, TESKE, Gwendoline J. D, FLORQUIN, Sandrine, SCHWEDE, Frank
Published in Journal of the American Society of Nephrology (01.07.2014)
Published in Journal of the American Society of Nephrology (01.07.2014)
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Rap1 Regulates E-cadherin-mediated Cell-Cell Adhesion
Price, Leo S, Hajdo-Milasinovic, Amra, Zhao, Jun, Zwartkruis, Fried J T, Collard, John G, Bos, Johannes L
Published in The Journal of biological chemistry (20.08.2004)
Published in The Journal of biological chemistry (20.08.2004)
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Spatial Regulation of Cyclic AMP-Epac1 Signaling in Cell Adhesion by ERM Proteins
Gloerich, Martijn, Ponsioen, Bas, Vliem, Marjolein J., Zhang, Zhongchun, Zhao, Jun, Kooistra, Matthijs R., Price, Leo S., Ritsma, Laila, Zwartkruis, Fried J., Rehmann, Holger, Jalink, Kees, Bos, Johannes L.
Published in Molecular and Cellular Biology (01.11.2010)
Published in Molecular and Cellular Biology (01.11.2010)
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Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles
Malas, Tareq B., Leonhard, Wouter N., Bange, Hester, Granchi, Zoraide, Hettne, Kristina M., Van Westen, Gerard J.P., Price, Leo S., 't Hoen, Peter A.C., Peters, Dorien J.M.
Published in EBioMedicine (01.01.2020)
Published in EBioMedicine (01.01.2020)
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Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility
Satomaa, Tero, Pynnönen, Henna, Vilkman, Anja, Kotiranta, Titta, Pitkänen, Virve, Heiskanen, Annamari, Herpers, Bram, Price, Leo, Helin, Jari, Saarinen, Juhani
Published in Antibodies (Basel) (22.03.2018)
Published in Antibodies (Basel) (22.03.2018)
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Calcium Signaling Regulates Translocation and Activation of Rac
Price, Leo S., Langeslag, Michiel, Klooster, Jean Paul ten, Hordijk, Peter L., Jalink, Kees, Collard, John G.
Published in The Journal of biological chemistry (10.10.2003)
Published in The Journal of biological chemistry (10.10.2003)
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Activation of Rac and Cdc42 by integrins mediates cell spreading
Price, L S, Leng, J, Schwartz, M A, Bokoch, G M
Published in Molecular biology of the cell (01.07.1998)
Published in Molecular biology of the cell (01.07.1998)
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Focal Adhesion Kinase Signaling Mediates Acute Renal Injury Induced by Ischemia/Reperfusion
Qin, Yu, Alderliesten, Maaike C, Stokman, Geurt, Pennekamp, Petra, Bonventre, Joseph V, de Heer, Emile, Ichimura, Takaharu, de Graauw, Marjo, Price, Leo S, van de Water, Bob
Published in The American journal of pathology (01.12.2011)
Published in The American journal of pathology (01.12.2011)
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Screening out irrelevant cell-based models of disease
Horvath, Peter, Aulner, Nathalie, Bickle, Marc, Davies, Anthony M., Nery, Elaine Del, Ebner, Daniel, Montoya, Maria C., Östling, Päivi, Pietiäinen, Vilja, Price, Leo S., Shorte, Spencer L., Turcatti, Gerardo, von Schantz, Carina, Carragher, Neil O.
Published in Nature reviews. Drug discovery (01.11.2016)
Published in Nature reviews. Drug discovery (01.11.2016)
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Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells
Verissimo, Carla S, Cheng, Sou, Puigvert, Jordi C, Qin, Yu, Vroon, Anne, van Deutekom, Judith, Price, Leo S, Danen, Erik H J, van de Water, Bob, Fitzsimons, Carlos P, Vreugdenhil, Erno
Published in The Journal of pharmacology and experimental therapeutics (01.07.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2012)
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A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies
Ramaiahgari, Sreenivasa C., den Braver, Michiel W., Herpers, Bram, Terpstra, Valeska, Commandeur, Jan N. M., van de Water, Bob, Price, Leo S.
Published in Archives of toxicology (01.05.2014)
Published in Archives of toxicology (01.05.2014)
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Journal Article
3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis
Booij, Tijmen H., Price, Leo S., Danen, Erik H. J.
Published in SLAS DISCOVERY: Advancing the Science of Drug Discovery (01.07.2019)
Published in SLAS DISCOVERY: Advancing the Science of Drug Discovery (01.07.2019)
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Book Review
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AF6 Negatively Regulates Rap1-induced Cell Adhesion
Zhang, Zhongchun, Rehmann, Holger, Price, Leo S., Riedl, Jurgen, Bos, Johannes L.
Published in The Journal of biological chemistry (30.09.2005)
Published in The Journal of biological chemistry (30.09.2005)
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Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective
Kanhai, Anish A., Bange, Hester, Verburg, Lotte, Dijkstra, Kyra L., Price, Leo S., Peters, Dorien J. M., Leonhard, Wouter N.
Published in Scientific reports (03.02.2020)
Published in Scientific reports (03.02.2020)
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