JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome
Del Bel, Kate L., MSc, Ragotte, Robert J., BSc, Saferali, Aabida, MSc, Lee, Susan, RN, Vercauteren, Suzanne M., MD PhD, Mostafavi, Sara A., PhD, Schreiber, Richard A., MD, Prendiville, Julie S., MD, Phang, Min S., MD, Halperin, Jess, MD, Au, Nicholas, MD, Dean, John M., MD BS, Jewels, Emily, RN, Junker, Anne K., MD, Rogers, Paul C., MB ChB MBA, Seear, Michael, MB ChB, McKinnon, Margaret L., MD, Turvey, Stuart E., MB BS, DPhil
Published in Journal of allergy and clinical immunology (01.06.2017)
Published in Journal of allergy and clinical immunology (01.06.2017)
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The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling
Klein, Theo, Fung, Shan-Yu, Renner, Florian, Blank, Michael A, Dufour, Antoine, Kang, Sohyeong, Bolger-Munro, Madison, Scurll, Joshua M, Priatel, John J, Schweigler, Patrick, Melkko, Samu, Gold, Michael R, Viner, Rosa I, Régnier, Catherine H, Turvey, Stuart E, Overall, Christopher M
Published in Nature communications (03.11.2015)
Published in Nature communications (03.11.2015)
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An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
Quancard, Jean, Klein, Theo, Fung, Shan-Yu, Renatus, Martin, Hughes, Nicola, Israël, Laura, Priatel, John J, Kang, Sohyeong, Blank, Michael A, Viner, Rosa I, Blank, Jutta, Schlapbach, Achim, Erbel, Paul, Kizhakkedathu, Jayachandran, Villard, Frédéric, Hersperger, René, Turvey, Stuart E, Eder, Joerg, Bornancin, Frédéric, Overall, Christopher M
Published in Nature chemical biology (01.03.2019)
Published in Nature chemical biology (01.03.2019)
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Combined immunodeficiency associated with homozygous MALT1 mutations
McKinnon, Margaret L., MD, Rozmus, Jacob, MD, Fung, Shan-Yu, PhD, Hirschfeld, Aaron F., MSc, Del Bel, Kate L., MSc, Thomas, Leah, BSc, Marr, Nico, Dr rer nat, Martin, Spencer D., BSc, Marwaha, Ashish K., BM, BCh, Priatel, John J., PhD, Tan, Rusung, MD, PhD, Senger, Christof, MD, Tsang, Angela, BSc, Prendiville, Julie, MD, Junker, Anne K., MD, Seear, Michael, MB, ChB, Schultz, Kirk R., MD, Sly, Laura M., PhD, Holt, Robert A., PhD, Patel, Millan S., MD, MSc, Friedman, Jan M., MD, PhD, Turvey, Stuart E., MBBS, DPhil
Published in Journal of allergy and clinical immunology (01.05.2014)
Published in Journal of allergy and clinical immunology (01.05.2014)
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Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation
Bolger-Munro, Madison, Choi, Kate, Scurll, Joshua M, Abraham, Libin, Chappell, Rhys S, Sheen, Duke, Dang-Lawson, May, Wu, Xufeng, Priatel, John J, Coombs, Daniel, Hammer, John A, Gold, Michael R
Published in eLife (03.06.2019)
Published in eLife (03.06.2019)
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The CaV1.4 Calcium Channel Is a Critical Regulator of T Cell Receptor Signaling and Naive T Cell Homeostasis
Omilusik, Kyla, Priatel, John J., Chen, Xiaoxi, Wang, Yiwen Teresa, Xu, Hongjian, Choi, Kyung Bok, Gopaul, Rayshad, McIntyre-Smith, Adam, Teh, Hung-Sia, Tan, Rusung, Bech-Hansen, N. Torben, Waterfield, Douglas, Fedida, David, Hunt, Simon V., Jefferies, Wilfred A.
Published in Immunity (Cambridge, Mass.) (23.09.2011)
Published in Immunity (Cambridge, Mass.) (23.09.2011)
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Cutting edge: Increased IL-17-secreting T cells in children with new-onset type 1 diabetes
Marwaha, Ashish K, Crome, Sarah Q, Panagiotopoulos, Constadina, Berg, Kyra B, Qin, Huilian, Ouyang, Qin, Xu, Lixin, Priatel, John J, Levings, Megan K, Tan, Rusung
Published in The Journal of immunology (1950) (01.10.2010)
Published in The Journal of immunology (1950) (01.10.2010)
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Deep Phenotyping by Mass Cytometry and Single-Cell RNA-Sequencing Reveals LYN-Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan
Roberts, Morgan E, Barvalia, Maunish, Silva, Jessica A.F.D, Cederberg, Rachel A, Chu, William, Wong, Amanda, Tai, Daven C, Chen, Sam, Matos, Israel, Priatel, John J, Cullis, Pieter R, Harder, Kenneth W
Published in Circulation research (08.05.2020)
Published in Circulation research (08.05.2020)
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Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen
Tsai, Kevin, Huang, Yu-Hsuan, Ma, Caixia, Baldwin, Troy A, Harder, Kenneth W, Vallance, Bruce A, Priatel, John J
Published in The Journal of immunology (1950) (15.07.2020)
Published in The Journal of immunology (1950) (15.07.2020)
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Innate immune control of EBV-infected B cells by invariant natural killer T cells
Chung, Brian K., Tsai, Kevin, Allan, Lenka L., Zheng, Dong Jun, Nie, Johnny C., Biggs, Catherine M., Hasan, Mohammad R., Kozak, Frederick K., van den Elzen, Peter, Priatel, John J., Tan, Rusung
Published in Blood (10.10.2013)
Published in Blood (10.10.2013)
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Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis
van Luijn, Marvin M, Kreft, Karim L, Jongsma, Marlieke L, Mes, Steven W, Wierenga-Wolf, Annet F, van Meurs, Marjan, Melief, Marie-José, der Kant, Rik van, Janssen, Lennert, Janssen, Hans, Tan, Rusung, Priatel, John J, Neefjes, Jacques, Laman, Jon D, Hintzen, Rogier Q
Published in Brain (London, England : 1878) (01.06.2015)
Published in Brain (London, England : 1878) (01.06.2015)
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The Role of Autoimmunity-Related Gene CLEC16A in the B Cell Receptor-Mediated HLA Class II Pathway
Rijvers, Liza, Melief, Marie-José, van Langelaar, Jamie, van der Vuurst de Vries, Roos M, Wierenga-Wolf, Annet F, Koetzier, Steven C, Priatel, John J, Jorritsma, Tineke, van Ham, S Marieke, Hintzen, Rogier Q, van Luijn, Marvin M
Published in The Journal of immunology (1950) (15.08.2020)
Published in The Journal of immunology (1950) (15.08.2020)
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The Ca(v)1.4 calcium channel is a critical regulator of T cell receptor signaling and naive T cell homeostasis
Omilusik, Kyla, Priatel, John J, Chen, Xiaoxi, Wang, Yiwen Teresa, Xu, Hongjian, Choi, Kyung Bok, Gopaul, Rayshad, McIntyre-Smith, Adam, Teh, Hung-Sia, Tan, Rusung, Bech-Hansen, N Torben, Waterfield, Douglas, Fedida, David, Hunt, Simon V, Jefferies, Wilfred A
Published in Immunity (Cambridge, Mass.) (23.09.2011)
Published in Immunity (Cambridge, Mass.) (23.09.2011)
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CCL22 Prevents Rejection of Mouse Islet Allografts and Induces Donor-Specific Tolerance
Montane, Joel, Obach, Merce, Alvarez, Sigrid, Bischoff, Loraine, Dai, Derek L., Soukhatcheva, Galina, Priatel, John J., Hardenberg, Gijs, Levings, Megan K., Tan, Rusung, Orban, Paul C., Verchere, C. Bruce
Published in Cell transplantation (01.10.2015)
Published in Cell transplantation (01.10.2015)
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Prevention of autoimmune diabetes and islet allograft rejection by beta cell expression of XIAP: Insight into possible mechanisms of local immunomodulation
Obach, Mercè, Hosseini-Tabatabaei, Azadeh, Montane, Joel, Wind, Katarina, Soukhatcheva, Galina, Dai, Derek, Priatel, John J., Orban, Paul C., Verchere, C. Bruce
Published in Molecular and cellular endocrinology (05.12.2018)
Published in Molecular and cellular endocrinology (05.12.2018)
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Natural Killer Cells From Children With Type 1 Diabetes Have Defects in NKG2D-Dependent Function and Signaling
HUILIAN QIN, LEE, I-Fang, PANAGIOTOPOULOS, Constadina, XIAOXIA WANG, CHU, Alvina D, UTZ, Paul J, PRIATEL, John J, RUSUNG TAN
Published in Diabetes (New York, N.Y.) (01.03.2011)
Published in Diabetes (New York, N.Y.) (01.03.2011)
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Highly Sensitive, Flow Cytometry-Based Measurement of Intestinal Permeability in Models of Experimental Colitis
Tsai, Kevin, Ma, Caixia, Han, Xiao, Allaire, Joannie, Lunken, Genelle R., Crowley, Shauna M., Yu, Hongbing, Jacobson, Kevan, Xia, Lijun, Priatel, John J., Vallance, Bruce A.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
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TNF Receptor Type 2 (p75) Functions as a Costimulator for Antigen-Driven T Cell Responses In Vivo
Kim, Edward Y, Priatel, John J, Teh, Soo-Jeet, Teh, Hung-Sia
Published in Journal of Immunology (15.01.2006)
Published in Journal of Immunology (15.01.2006)
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The importance of functional validation after next‐generation sequencing: evaluation of a novel CARD11 variant
Lu, Henry Y., Sharma, Mehul, Biggs, Catherine M., Huang, Yu‐Hsuan, Shopsowitz, Kevin E., Frosk, Patrick, Priatel, John J., Rubin, Tamar S., Turvey, Stuart E.
Published in Pediatric allergy and immunology (01.09.2018)
Published in Pediatric allergy and immunology (01.09.2018)
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