N-Phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amines as Potent and Selective Inhibitors of Glycogen Synthase Kinase 3 with Good Cellular Efficacy
Tavares, Francis X, Boucheron, Joyce A, Dickerson, Scott H, Griffin, Robert J, Preugschat, Frank, Thomson, Stephen A, Wang, Tony Y, Zhou, Hui-Qiang
Published in Journal of medicinal chemistry (09.09.2004)
Published in Journal of medicinal chemistry (09.09.2004)
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Novel pyrazolopyrimidine derivatives as GSK-3 inhibitors
PEAT, Andrew J, BOUCHERON, Joyce A, WANG, Tony Y, ZHOU, Huiqiang Q, THOMSON, Stephen A, DICKERSON, Scott H, GARRIDO, Dulce, MILLS, Wendy, PECKHAM, Jennifer, PREUGSCHAT, Frank, SMALLEY, Terrence, SCHWEIKER, Stephanie L, WILSON, Jayme R
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
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Synthesis and evaluation of novel heterocyclic inhibitors of GSK-3
Smalley, Terrence L., Peat, Andrew J., Boucheron, Joyce A., Dickerson, Scott, Garrido, Dulce, Preugschat, Frank, Schweiker, Stephanie L., Thomson, Stephen A., Wang, Tony Y.
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
Published in Bioorganic & medicinal chemistry letters (15.04.2006)
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Discovery and in vitro evaluation of potent kinase inhibitors: Pyrido[1′,2′:1,5]pyrazolo[3,4- d]pyrimidines
Alberti, Michael J., Auten, Elizabeth P., Lackey, Karen E., McDonald, Octerloney B., Wood, Edgar R., Preugschat, Frank, Cutler, Geoffrey J., Kane-Carson, Laurie, Liu, Wei, Jung, David K.
Published in Bioorganic & medicinal chemistry letters (15.08.2005)
Published in Bioorganic & medicinal chemistry letters (15.08.2005)
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Dengue 2 Virus NS2B and NS3 Form a Stable Complex That Can Cleave NS3 within the Helicase Domain
Arias, Carlos F., Preugschat, Frank, Strauss, James H.
Published in Virology (New York, N.Y.) (01.04.1993)
Published in Virology (New York, N.Y.) (01.04.1993)
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Kinetic Analysis of the Effects of Mutagenesis of W501 and V432 of the Hepatitis C Virus NS3 Helicase Domain on ATPase and Strand-Separating Activity
Preugschat, Frank, Danger, Dana P, Carter, Luke H, Davis, Roderick G, Porter, David J. T
Published in Biochemistry (Easton) (02.05.2000)
Published in Biochemistry (Easton) (02.05.2000)
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Product release is the major contributor to kcat for the hepatitis C virus helicase-catalyzed strand separation of short duplex DNA
Porter, D J, Short, S A, Hanlon, M H, Preugschat, F, Wilson, J E, Willard, Jr, D H, Consler, T G
Published in The Journal of biological chemistry (24.07.1998)
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Published in The Journal of biological chemistry (24.07.1998)
Journal Article
Product release is the major contributor to k sub(cat) for the hepatitis C virus helicase-catalyzed strand separation of short duplex DNA
Porter, DJT, Short, SA, Hanlon, M H, Preugschat, F, Wilson, JE, Willard, DH Jr, Consler, T G
Published in The Journal of biological chemistry (01.07.1998)
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Published in The Journal of biological chemistry (01.07.1998)
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Expression and characterization of the HCV NS3 helicase domain
Preugschat, F, Hanlon, M H, Rink, M J, Clarke, B E, Porter, D J
Published in Methods in molecular medicine (1999)
Published in Methods in molecular medicine (1999)
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Actin genes from the sea star Pisaster ochraceus
Kovesdi, I, Preugschat, F, Stuerzl, M, Smith, MJ
Published in Biochimica et biophysica acta, Protein structure and molecular enzymology (01.01.1984)
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Published in Biochimica et biophysica acta, Protein structure and molecular enzymology (01.01.1984)
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Actin genes from the sea star Pisaster ochraceus
Kovesdi, Imre, Preugschat, Frank, Stuerzl, Margaret, Smith, Michael J.
Published in Biochimica et biophysica acta (15.05.1984)
Published in Biochimica et biophysica acta (15.05.1984)
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