Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis
Roth, Aleeza J, Ooi, Joshua D, Hess, Jacob J, van Timmeren, Mirjan M, Berg, Elisabeth A, Poulton, Caroline E, McGregor, JulieAnne, Burkart, Madelyn, Hogan, Susan L, Hu, Yichun, Winnik, Witold, Nachman, Patrick H, Stegeman, Coen A, Niles, John, Heeringa, Peter, Kitching, A Richard, Holdsworth, Stephen, Jennette, J Charles, Preston, Gloria A, Falk, Ronald J
Published in The Journal of clinical investigation (01.04.2013)
Published in The Journal of clinical investigation (01.04.2013)
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Journal Article
High basal activity of the PTPN22 gain-of-function variant blunts leukocyte responsiveness negatively affecting IL-10 production in ANCA vasculitis
Cao, Yali, Yang, Jiajin, Colby, Kerry, Hogan, Susan L, Hu, Yichun, Jennette, Caroline E, Berg, Elisabeth A, Zhang, Youkang, Jennette, J Charles, Falk, Ronald J, Preston, Gloria A
Published in PloS one (03.08.2012)
Published in PloS one (03.08.2012)
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Journal Article
Myeloperoxidase Interacts with Endothelial Cell-Surface Cytokeratin 1 and Modulates Bradykinin Production by the Plasma Kallikrein-Kinin System
Astern‡, Joshua M, Pendergraft, William F, Falk‡, Ronald J, Jennette‡, J. Charles, Schmaier, Alvin H, Mahdi, Fakhri, Preston‡, Gloria A
Published in The American journal of pathology (01.07.2007)
Published in The American journal of pathology (01.07.2007)
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Journal Article
Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Have Defective Treg Cell Function Exacerbated by the Presence of a Suppression‐Resistant Effector Cell Population
Free, Meghan E., Bunch, Donna O'Dell, McGregor, Julie Anne, Jones, Britta E., Berg, Elisabeth A., Hogan, Susan L., Hu, Yichun, Preston, Gloria A., Jennette, J. Charles, Falk, Ronald J., Su, Maureen A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2013)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2013)
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Journal Article
Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis
Ciavatta, Dominic J, Yang, Jiajin, Preston, Gloria A, Badhwar, Anshul K, Xiao, Hong, Hewins, Peter, Nester, Carla M, Pendergraft, 3rd, William F, Magnuson, Terry R, Jennette, J Charles, Falk, Ronald J
Published in The Journal of clinical investigation (01.09.2010)
Published in The Journal of clinical investigation (01.09.2010)
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Journal Article
Autoantigen complementarity: a new theory implicating complementary proteins as initiators of autoimmune disease
PENDERGRAFT, William F, PRESSLER, Barrak M, JENNETTE, J. Charles, FALK, Ronald J, PRESTON, Gloria A
Published in Journal of molecular medicine (Berlin, Germany) (01.01.2005)
Published in Journal of molecular medicine (Berlin, Germany) (01.01.2005)
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Journal Article
Anti―LAMP-2 Antibodies Are Not Prevalent in Patients With Antineutrophil Cytoplasmic Autoantibody Glomerulonephritis
ROTH, Aleeza J, BROWN, Michael C, YANG, Jia-Jin, BERG, Elisabeth A, NILES, John, CHARLES JENNETTE, J, PRESTON, Gloria A, FALK, Ronald J, NEAL SMITH, Rex, BADHWAR, Anshul K, PARENTE, Oscar, CHUL CHUNG, Hyun, O'DELL BUNCH, Donna, MCGREGOR, Julieanne G, HOGAN, Susan L, YICHUN HU
Published in Journal of the American Society of Nephrology (01.03.2012)
Published in Journal of the American Society of Nephrology (01.03.2012)
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Journal Article
Expression profile of leukocyte genes activated by anti-neutrophil cytoplasmic autoantibodies (ANCA)
Yang, Jia Jin, Preston, Gloria A., Alcorta, David A., Waga, Iwao, Munger, William E., Hogan, Susan L., Sekura, Stephen B., Phillips, Brian D., Thomas, Robin P., Jennette, J. Charles, Falk, Ronald J.
Published in Kidney international (01.11.2002)
Published in Kidney international (01.11.2002)
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Journal Article
Conference Proceeding
DRB115 Allele Is a Risk Factor for PR3-ANCA Disease in African Americans
YALI CAO, SCHMITZ, John L, FALK, Ronald J, PRESTON, Gloria A, JIAJIN YANG, HOGAN, Susan L, BUNCH, Donna, YICHUN HU, JENNETTE, Caroline E, BERG, Elisabeth A, ARNETT, Frank C, JENNETTE, J. Charles
Published in Journal of the American Society of Nephrology (01.06.2011)
Published in Journal of the American Society of Nephrology (01.06.2011)
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Journal Article
Dysregulation of autoantigen genes in ANCA-associated vasculitis involves alternative transcripts and new protein synthesis
McInnis, Elizabeth A, Badhwar, Anshul K, Muthigi, Akhil, Lardinois, Olivier M, Allred, S Colby, Yang, Jiajin, Free, Meghan E, Jennette, J Charles, Preston, Gloria A, Falk, Ronald J, Ciavatta, Dominic J
Published in Journal of the American Society of Nephrology (01.02.2015)
Published in Journal of the American Society of Nephrology (01.02.2015)
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Journal Article
Autoantigen complementarity and its contributions to hallmarks of autoimmune disease
Pendergraft, William F., Badhwar, Anshul K., Preston, Gloria A.
Published in Journal of theoretical biology (21.06.2015)
Published in Journal of theoretical biology (21.06.2015)
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Journal Article
Antibodies with Dual Reactivity to Plasminogen and Complementary PR3 in PR3-ANCA Vasculitis
BAUTZ, David J, PRESTON, Gloria A, FALK, Ronald J, LIONAKI, Sofia, HEWINS, Peter, WOLBERG, Alisa S, JIA JIN YANG, HOGAN, Susan L, CHIN, Hyunsook, MOLL, Stephan, JENNETTE, J. Charles
Published in Journal of the American Society of Nephrology (01.12.2008)
Published in Journal of the American Society of Nephrology (01.12.2008)
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Journal Article
Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by ‘autoantigen complementarity’
Reynolds, John, Preston, Gloria A, Pressler, Barrak M, Hewins, Peter, Brown, Michael, Roth, Aleeza, Alderman, Elizabeth, Bunch, Donna, Jennette, J. Charles, Cook, H. Terence, Falk, Ronald J, Pusey, Charles D
Published in Journal of autoimmunity (01.05.2015)
Published in Journal of autoimmunity (01.05.2015)
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Journal Article
Serum Matrix Metalloproteinases MMP-2 and MMP-3 Levels in Dialysis Patients Vary Independently of CRP and IL-6 Levels
Preston, Gloria A., Barrett, Cheri V., Alcorta, David A., Hogan, Susan L., Dinwiddie, Lesley, Jennette, J. Charles, Falk, Ronald J.
Published in Nephron (01.12.2002)
Published in Nephron (01.12.2002)
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Journal Article
ANCA patients have T cells responsive to complementary PR-3 antigen
Yang, Jiajin, Bautz, David J., Lionaki, Sofia, Hogan, Susan L., Chin, Hyunsook, Tisch, Roland M., Schmitz, John L., Pressler, Barrak M., Jennette, J. Charles, Falk, Ronald J., Preston, Gloria A.
Published in Kidney international (01.11.2008)
Published in Kidney international (01.11.2008)
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Journal Article
Understanding the pathogenesis of ANCA: where are we today?
Preston, Gloria A, Yang, Jia Jin, Xiao, Hong, Falk, Ronald J
Published in Cleveland Clinic journal of medicine (01.04.2002)
Published in Cleveland Clinic journal of medicine (01.04.2002)
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Journal Article
Autoimmunity is triggered by cPR-3(105-201), a protein complementary to human autoantigen proteinase-3
Falk, Ronald J, Pendergraft, William F, Preston, Gloria A, Shah, Ruchir R, Tropsha, Alexander, Carter, Charles W, Jennette, J Charles
Published in Nature medicine (01.01.2004)
Published in Nature medicine (01.01.2004)
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Journal Article
Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis
JIA JIN YANG, PENDERGRAFT, William F, ALCORTA, David A, NACHMAN, Patrick H, HOGAN, Susan L, THOMAS, Robin P, SULLIVAN, Pamela, JENNETTE, J. Charles, FALK, Ronald J, PRESTON, Gloria A
Published in Journal of the American Society of Nephrology (01.08.2004)
Published in Journal of the American Society of Nephrology (01.08.2004)
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Journal Article
Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-κB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways
PRESTON, Gloria A, ZARELLA, Christopher S, PENDERGRAFT, William F, RUDOLPH, Earl H, JIA JIN YANG, SEKURA, Stephen B, JENNETTE, J. Charles, FALK, Ronald J
Published in Journal of the American Society of Nephrology (01.12.2002)
Published in Journal of the American Society of Nephrology (01.12.2002)
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Journal Article
Longitudinal studies of patients with ANCA vasculitis demonstrate concurrent reactivity to complementary PR3 protein segments cPR3m and cPR3C and with no reactivity to cPR3N
Hewins, Peter, Belmonte, Frances, Charles Jennette, J., Falk, Ronald J., Preston, Gloria A.
Published in Autoimmunity (Chur, Switzerland) (01.03.2011)
Published in Autoimmunity (Chur, Switzerland) (01.03.2011)
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