Current and future treatment of amyloid diseases
Ankarcrona, M., Winblad, B., Monteiro, C., Fearns, C., Powers, E. T., Johansson, J., Westermark, G. T., Presto, J., Ericzon, B.‐G., Kelly, J. W.
Published in Journal of internal medicine (01.08.2016)
Published in Journal of internal medicine (01.08.2016)
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Biological therapies in the treatment of cutaneous lupus erythematosus
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Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons
Galan-Acosta, L., Sierra, C., Leppert, A., Pouliopoulos, A.N., Kwon, N., Noel, R.L., Tambaro, S., Presto, J., Nilsson, P., Konofagou, E.E., Johansson, J.
Published in Molecular and cellular neuroscience (01.06.2020)
Published in Molecular and cellular neuroscience (01.06.2020)
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Computerized planimetry to assess clinical responsiveness in a phase II randomized trial of topical R333 for discoid lupus erythematosus
Presto, J.K., Okon, L.G., Feng, R., Wallace, D.J., Furie, R., Fiorentino, D., Werth, V.P.
Published in British journal of dermatology (1951) (01.06.2018)
Published in British journal of dermatology (1951) (01.06.2018)
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BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells
Del Campo, M., Oliveira, C. R., Scheper, W., Zwart, R., Korth, C., Müller-Schiffmann, A., Kostallas, G., Biverstal, H., Presto, J., Johansson, J., Hoozemans, J. J., Pereira, C. F., Teunissen, C. E.
Published in Cellular and molecular life sciences : CMLS (01.04.2015)
Published in Cellular and molecular life sciences : CMLS (01.04.2015)
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Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
Arosio, Paolo, Michaels, Thomas C. T., Linse, Sara, Månsson, Cecilia, Emanuelsson, Cecilia, Presto, Jenny, Johansson, Jan, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Published in Nature communications (24.03.2016)
Published in Nature communications (24.03.2016)
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A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
Cohen, Samuel I A, Arosio, Paolo, Presto, Jenny, Kurudenkandy, Firoz Roshan, Biverstål, Henrik, Dolfe, Lisa, Dunning, Christopher, Yang, Xiaoting, Frohm, Birgitta, Vendruscolo, Michele, Johansson, Jan, Dobson, Christopher M, Fisahn, André, Knowles, Tuomas P J, Linse, Sara
Published in Nature structural & molecular biology (01.03.2015)
Published in Nature structural & molecular biology (01.03.2015)
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The BRICHOS Domain, Amyloid Fibril Formation, and Their Relationship
Knight, Stefan D, Presto, Jenny, Linse, Sara, Johansson, Jan
Published in Biochemistry (Easton) (29.10.2013)
Published in Biochemistry (Easton) (29.10.2013)
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Amyloid-β-induced action potential desynchronization and degradation of hippocampal gamma oscillations is prevented by interference with peptide conformation change and aggregation
Kurudenkandy, Firoz Roshan, Zilberter, Misha, Biverstål, Henrik, Presto, Jenny, Honcharenko, Dmytro, Strömberg, Roger, Johansson, Jan, Winblad, Bengt, Fisahn, André
Published in The Journal of neuroscience (20.08.2014)
Published in The Journal of neuroscience (20.08.2014)
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Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state
Chen, Gefei, Abelein, Axel, Nilsson, Harriet E., Leppert, Axel, Andrade-Talavera, Yuniesky, Tambaro, Simone, Hemmingsson, Lovisa, Roshan, Firoz, Landreh, Michael, Biverstål, Henrik, Koeck, Philip J. B., Presto, Jenny, Hebert, Hans, Fisahn, André, Johansson, Jan
Published in Nature communications (12.12.2017)
Published in Nature communications (12.12.2017)
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BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells
Oskarsson, Marie E., Hermansson, Erik, Wang, Ye, Welsh, Nils, Presto, Jenny, Johansson, Jan, Westermark, Gunilla T.
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2018)
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BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide
Willander, Hanna, Presto, Jenny, Askarieh, Glareh, Biverstål, Henrik, Frohm, Birgitta, Knight, Stefan D., Johansson, Jan, Linse, Sara
Published in The Journal of biological chemistry (07.09.2012)
Published in The Journal of biological chemistry (07.09.2012)
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Specific Chaperones and Regulatory Domains in Control of Amyloid Formation
Landreh, Michael, Rising, Anna, Presto, Jenny, Jörnvall, Hans, Johansson, Jan
Published in The Journal of biological chemistry (30.10.2015)
Published in The Journal of biological chemistry (30.10.2015)
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Blood–brain and blood–cerebrospinal fluid passage of BRICHOS domains from two molecular chaperones in mice
Tambaro, Simone, Galan-Acosta, Lorena, Leppert, Axel, Chen, Gefei, Biverstål, Henrik, Presto, Jenny, Nilsson, Per, Johansson, Jan
Published in The Journal of biological chemistry (22.02.2019)
Published in The Journal of biological chemistry (22.02.2019)
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Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation
Gerenu, Gorka, Persson, Torbjörn, Goikolea, Julen, Calvo-Garrido, Javier, Loera-Valencia, Raúl, Pottmeier, Philipp, Santiago, Cesar, Poska, Helen, Presto, Jenny, Cedazo-Minguez, Angel
Published in Molecular psychiatry (01.04.2021)
Published in Molecular psychiatry (01.04.2021)
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Dementia-related Bri2 BRICHOS is a versatile molecular chaperone that efficiently inhibits Aβ42 toxicity in Drosophila
Poska, Helen, Haslbeck, Martin, Kurudenkandy, Firoz Roshan, Hermansson, Erik, Chen, Gefei, Kostallas, George, Abelein, Axel, Biverstål, Henrik, Crux, Sophie, Fisahn, André, Presto, Jenny, Johansson, Jan
Published in Biochemical journal (2016)
Published in Biochemical journal (2016)
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The initial rise in GIP secretion during OGTT correlates with the initial suppression of glucagon secretion in adolescents with obesity and type 2 diabetes
Kristinsson, Hjalti, Manell, Hannes, Dahlbom, Marie, Presto, J., Garedal, C., Ritzen, H., Vilhelmsson, M., Kilstedt, E., Johnson, F., Stenberg, H., Forslund, Anders, Bergsten, P
Published in Diabetologia (2018)
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Published in Diabetologia (2018)
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High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins
Vincenz‐Donnelly, Lisa, Holthusen, Hauke, Körner, Roman, Hansen, Erik C, Presto, Jenny, Johansson, Jan, Sawarkar, Ritwick, Hartl, F Ulrich, Hipp, Mark S
Published in The EMBO journal (01.02.2018)
Published in The EMBO journal (01.02.2018)
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