A Two-in-One Antibody against HER3 and EGFR Has Superior Inhibitory Activity Compared with Monospecific Antibodies
Schaefer, Gabriele, Haber, Lauric, Crocker, Lisa M., Shia, Steven, Shao, Lily, Dowbenko, Donald, Totpal, Klara, Wong, Anne, Lee, Chingwei V., Stawicki, Scott, Clark, Robyn, Fields, Carter, Lewis Phillips, Gail D., Prell, Rodney A., Danilenko, Dimitry M., Franke, Yvonne, Stephan, Jean-Philippe, Hwang, Jiyoung, Wu, Yan, Bostrom, Jenny, Sliwkowski, Mark X., Fuh, Germaine, Eigenbrot, Charles
Published in Cancer cell (18.10.2011)
Published in Cancer cell (18.10.2011)
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An anti-CD3/anti–CLL-1 bispecific antibody for the treatment of acute myeloid leukemia
Leong, Steven R., Sukumaran, Siddharth, Hristopoulos, Maria, Totpal, Klara, Stainton, Shannon, Lu, Elizabeth, Wong, Alfred, Tam, Lucinda, Newman, Robert, Vuillemenot, Brian R., Ellerman, Diego, Gu, Chen, Mathieu, Mary, Dennis, Mark S., Nguyen, Allen, Zheng, Bing, Zhang, Crystal, Lee, Genee, Chu, Yu-Waye, Prell, Rodney A., Lin, Kedan, Laing, Steven T., Polson, Andrew G.
Published in Blood (02.02.2017)
Published in Blood (02.02.2017)
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Avidity-based binding to HER2 results in selective killing of HER2-overexpressing cells by anti-HER2/CD3
Slaga, Dionysos, Ellerman, Diego, Lombana, T Noelle, Vij, Rajesh, Li, Ji, Hristopoulos, Maria, Clark, Robyn, Johnston, Jennifer, Shelton, Amy, Mai, Elaine, Gadkar, Kapil, Lo, Amy A, Koerber, James T, Totpal, Klara, Prell, Rodney, Lee, Genee, Spiess, Christoph, Junttila, Teemu T
Published in Science translational medicine (17.10.2018)
Published in Science translational medicine (17.10.2018)
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Changing the drug development and therapeutic paradigm with biologic drug combinations and bispecifics: How to choose between these two approaches?
Zheng, Songmao, Prell, Rodney, Sheng, Jennifer, Wang, Yow‐Ming, Hamuro, Lora
Published in Clinical and translational science (01.09.2022)
Published in Clinical and translational science (01.09.2022)
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Journal Article
Vascular Endothelial Growth Factor Blockade Reduces Intratumoral Regulatory T Cells and Enhances the Efficacy of a GM-CSF–Secreting Cancer Immunotherapy
LI, Betty, LALANI, Alshad S, HARDING, Thomas C, LUAN, Bo, KOPRIVNIKAR, Kathryn, HUANTU, Guang, PRELL, Rodney, VAN ROEY, Melinda J, SIMMONS, Andrew D, JOOSS, Karin
Published in Clinical cancer research (15.11.2006)
Published in Clinical cancer research (15.11.2006)
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Journal Article
In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection
Rao, Gautham K, Prell, Rodney A, Laing, Steven T, Burleson, Stefanie C M, Nguyen, Allen, McBride, Jacqueline M, Zhang, Crystal, Sheinson, Daniel, Halpern, Wendy G
Published in Toxicological sciences (01.06.2019)
Published in Toxicological sciences (01.06.2019)
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Development of a nonhuman primate challenge model to evaluate CD8 + T cell responses to an adenovirus-based vaccine expressing SIV proteins upon repeat-dose treatment with checkpoint inhibitors
Graveline, Richard, Haida, Morad, Dumont, Carolyne, Poulin, Dominic, Poitout-Belissent, Florence, Samadfam, Rana, Kronenberg, Sven, Regenass-Lechner, Franziska, Prell, Rodney, Piche, Marie-Soleil
Published in mAbs (01.01.2022)
Published in mAbs (01.01.2022)
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Engagement of the OX-40 Receptor In Vivo Enhances Antitumor Immunity
Weinberg, Andrew D, Rivera, Martin-Muy, Prell, Rodney, Morris, Arden, Ramstad, Trygg, Vetto, John T, Urba, Walter J, Alvord, Gregory, Bunce, Campbell, Shields, John
Published in The Journal of immunology (1950) (15.02.2000)
Published in The Journal of immunology (1950) (15.02.2000)
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Efficacy of GM-CSF-producing tumor vaccine after docetaxel chemotherapy in mice bearing established Lewis lung carcinoma
Chu, Yiwei, Wang, Li-Xin, Yang, Guojun, Ross, Helen J, Urba, Walter J, Prell, Rodney, Jooss, Karin, Xiong, Sidong, Hu, Hong-Ming
Published in Journal of immunotherapy (1997) (01.07.2006)
Published in Journal of immunotherapy (1997) (01.07.2006)
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Activation of Immature Hepatic NK Cells As Immunotherapy for Liver Metastatic Disease
Bahjat, Keith S, Prell, Rodney A, Allen, Heather E, Liu, Weiqun, Lemmens, Edward E, Leong, Meredith L, Portnoy, Daniel A, Dubensky, Thomas W., Jr, Brockstedt, Dirk G, Giedlin, Martin A
Published in The Journal of immunology (1950) (01.12.2007)
Published in The Journal of immunology (1950) (01.12.2007)
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Journal Article
OX40-Mediated Memory T Cell Generation Is TNF Receptor-Associated Factor 2 Dependent
Prell, Rodney A, Evans, Dean E, Thalhofer, Colin, Shi, Tom, Funatake, Castle, Weinberg, Andrew D
Published in The Journal of immunology (1950) (01.12.2003)
Published in The Journal of immunology (1950) (01.12.2003)
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Patient-derived skin MicroOrganoSpheres and clinical response to immunotherapy
Chakraborty, Rikhia, Fagan-Solis, Katerina, DeVilla, Jessica, Recaldin, Timothy, Bscheider, Michael, Gjorevski, Nikolche, Fullerton, Aaron, Prell, Rodney, Khan, Zia, Wang, Zhaohui, Ding, Shengli, Glass, Carolyn, Jeck, William, McCall, Shannon J., Beasley, Georgia, Mohindra, Rajat, Hsu, Shiaowen David, Chandler, G Scott, Shen, Xiling, Roth, Adrian B
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Current nonclinical approaches for immune assessments of immuno-oncology biotherapeutics
Grimaldi, Christine, Ibraghimov, Alex, Kiessling, Andrea, Rattel, Benno, Ji, Changhua, Fuller, Claudette L., Brennan, Frank R., Regenass-Lechner, Franziska, Shenton, Jacintha, Price, Karen D., Piché, Marie-Soleil, Steeves, Meredith A., Prell, Rodney, Dudal, Sherri, Kronenberg, Sven, Freebern, Wendy, Blanset, Diann
Published in Drug discovery today (01.02.2023)
Published in Drug discovery today (01.02.2023)
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Target arm affinities determine preclinical efficacy and safety of anti-HER2/CD3 bispecific antibody
Staflin, Karin, Zuch de Zafra, Christina L, Schutt, Leah K, Clark, Vanessa, Zhong, Fiona, Hristopoulos, Maria, Clark, Robyn, Li, Ji, Mathieu, Mary, Chen, Xiaocheng, Johnston, Jennifer, Low, Justin, Ybarra, Ryan, Slaga, Dionysos, Yang, Jihong, Ovacik, Meric, Dybdal, Noël O, Totpal, Klara, Junttila, Melissa R, Ellerman, Diego, Lee, Genee, Dennis, Mark S, Prell, Rodney, Junttila, Teemu T
Published in JCI insight (09.04.2020)
Published in JCI insight (09.04.2020)
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