Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs
Nikolai, Bryan C., Jain, Prashi, Cardenas, David L., York, Brian, Feng, Qin, McKenna, Neil J., Dasgupta, Subhamoy, Lonard, David M., O’Malley, Bert W.
Published in Scientific reports (09.02.2021)
Published in Scientific reports (09.02.2021)
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Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery
Chang, Lyra, Campbell, James, Raji, Idris O., Guduru, Shiva K. R., Kandel, Prasanna, Nguyen, Michelle, Liu, Steven, Tran, Kevin, Venugopal, Navneet K., Taylor, Bethany C., Holt, Matthew V., Young, Nicolas L., Samuel, Errol L. G., Jain, Prashi, Santini, Conrad, Sankaran, Banumathi, MacKenzie, Kevin R., Young, Damian W.
Published in Scientific reports (13.01.2021)
Published in Scientific reports (13.01.2021)
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Journal Article
High-Throughput Screening, Discovery, and Optimization To Develop a Benzofuran Class of Hepatitis C Virus Inhibitors
He, Shanshan, Jain, Prashi, Lin, Billy, Ferrer, Marc, Hu, Zongyi, Southall, Noel, Hu, Xin, Zheng, Wei, Neuenswander, Benjamin, Cho, Chul-Hee, Chen, Yu, Worlikar, Shilpa A, Aubé, Jeffrey, Larock, Richard C, Schoenen, Frank J, Marugan, Juan J, Liang, T. Jake, Frankowski, Kevin J
Published in ACS combinatorial science (12.10.2015)
Published in ACS combinatorial science (12.10.2015)
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Journal Article
Cyclin-Dependent Kinase 5 (CDK5) Controls Melanoma Cell Motility, Invasiveness, and Metastatic Spread—Identification of a Promising Novel therapeutic target
Bisht, Savita, Nolting, Jens, Schütte, Ute, Haarmann, Jens, Jain, Prashi, Shah, Dhruv, Brossart, Peter, Flaherty, Patrick, Feldmann, Georg
Published in Translational oncology (01.08.2015)
Published in Translational oncology (01.08.2015)
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Journal Article
Solution-Phase Synthesis of a Diverse Library of Benzisoxazoles Utilizing the [3 + 2] Cycloaddition of in Situ-Generated Nitrile Oxides and Arynes
Dubrovskiy, Anton V, Jain, Prashi, Shi, Feng, Lushington, Gerald H, Santini, Conrad, Porubsky, Patrick, Larock, Richard C
Published in ACS combinatorial science (08.04.2013)
Published in ACS combinatorial science (08.04.2013)
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Journal Article
Steroid receptor coactivator 3 is a key modulator of regulatory T cell-mediated tumor evasion
Han, Sang Jun, Jain, Prashi, Gilad, Yosef, Xia, Yan, Sung, Nuri, Park, Mi Jin, Dean, Adam M, Lanz, Rainer B, Xu, Jianming, Dacso, Clifford C, Lonard, David M, O'Malley, Bert W
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2023)
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Journal Article
Synthesis of Enantiomerically Pure 6‑Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production
Chamakuri, Srinivas, Jain, Prashi, Reddy Guduru, Shiva Krishna, Arney, J. Winston, MacKenzie, Kevin R, Santini, Conrad, Young, Damian W
Published in Journal of organic chemistry (15.06.2018)
Published in Journal of organic chemistry (15.06.2018)
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Journal Article
Development of improved SRC-3 inhibitors as breast cancer therapeutic agents
Qin, Li, Chen, Jianwei, Lu, Dong, Jain, Prashi, Yu, Yang, Cardenas, David, Peng, Xiaohui, Yu, Xiaobin, Xu, Jianming, Wang, Jin, O’Malley, Bert W, Lonard, David M
Published in Endocrine-related cancer (01.10.2021)
Published in Endocrine-related cancer (01.10.2021)
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Journal Article
Development of pyrimidone D1 dopamine receptor positive allosteric modulators
Luderman, Kathryn D., Jain, Prashi, Benjamin Free, R., Conroy, Jennie L., Aubé, Jeffrey, Sibley, David R., Frankowski, Kevin J.
Published in Bioorganic & medicinal chemistry letters (01.01.2021)
Published in Bioorganic & medicinal chemistry letters (01.01.2021)
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Journal Article
Identification of Positive Allosteric Modulators of the D 1 Dopamine Receptor That Act at Diverse Binding Sites
Luderman, Kathryn D, Conroy, Jennie L, Free, R Benjamin, Southall, Noel, Ferrer, Marc, Sanchez-Soto, Marta, Moritz, Amy E, Willette, Blair K A, Fyfe, Tim J, Jain, Prashi, Titus, Steve, Hazelwood, Lisa A, Aubé, Jeffrey, Lane, J Robert, Frankowski, Kevin J, Sibley, David R
Published in Molecular pharmacology (01.10.2018)
Published in Molecular pharmacology (01.10.2018)
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Journal Article
Synthesis of Enantiomerically Pure 5‑Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production
Jain, Prashi, Raji, Idris O, Chamakuri, Srinivas, MacKenzie, Kevin R, Ebright, Brandon T, Santini, Conrad, Young, Damian W
Published in Journal of organic chemistry (17.05.2019)
Published in Journal of organic chemistry (17.05.2019)
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Journal Article
Synthesis of a Family of Spirocyclic Scaffolds: Building Blocks for the Exploration of Chemical Space
Kumar, Sarvesh, Thornton, Paul D, Painter, Thomas O, Jain, Prashi, Downard, Jared, Douglas, Justin T, Santini, Conrad
Published in Journal of organic chemistry (05.07.2013)
Published in Journal of organic chemistry (05.07.2013)
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Journal Article
Correction to Synthesis of Enantiomerically Pure 6‑Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production
Chamakuri, Srinivas, Jain, Prashi, Guduru, Shiva Reddy Krishna, Arney, J. Winston, MacKenzie, Kevin R, Santini, Conrad, Young, Damian W
Published in Journal of organic chemistry (05.04.2019)
Published in Journal of organic chemistry (05.04.2019)
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Journal Article
Chemical Catalysis Guides Structural Identification for the Major In Vivo Metabolite of the BET Inhibitor JQ1
Holmes, Secondra, Jain, Prashi, Rodriguez, Kenneth Guzman, Williams, Jade, Yu, Zhifeng, Cerda-Smith, Christian, Samuel, Errol L. G., Campbell, James, Hakenjos, John Michael, Monsivais, Diana, Li, Feng, Chamakuri, Srinivas, Matzuk, Martin M., Santini, Conrad, MacKenzie, Kevin R., Young, Damian W.
Published in ACS medicinal chemistry letters (11.01.2024)
Published in ACS medicinal chemistry letters (11.01.2024)
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Journal Article
Metabolism of JQ1, an inhibitor of BET bromodomain proteins, in human and mouse liver microsomes
Li, Feng, MacKenzie, Kevin R, Jain, Prashi, Santini, Conrad, Young, Damian W, Matzuk, Martin M
Published in Biology of reproduction (14.04.2020)
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Published in Biology of reproduction (14.04.2020)
Journal Article
Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites
Luderman, Kathryn D, Conroy, Jennie L, Free, R Benjamin, Southall, Noel, Ferrer, Marc, Sanchez-Soto, Marta, Moritz, Amy E, Willette, Blair K A, Fyfe, Tim J, Jain, Prashi, Titus, Steve, Hazelwood, Lisa A, Aubé, Jeffrey, Lane, J Robert, Frankowski, Kevin J, Sibley, David R
Published in Molecular pharmacology (01.10.2018)
Published in Molecular pharmacology (01.10.2018)
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Journal Article
Design, synthesis, and testing of an 6-O-linked series of benzimidazole based inhibitors of CDK5/p25
Jain, Prashi, Flaherty, Patrick T., Yi, Shuyan, Chopra, Ishveen, Bleasdell, Gwenyth, Lipay, Josh, Ferandin, Yoan, Meijer, Laurent, Madura, Jeffry D.
Published in Bioorganic & medicinal chemistry (01.01.2011)
Published in Bioorganic & medicinal chemistry (01.01.2011)
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