Structural basis for a complex I mutation that blocks pathological ROS production
Yin, Zhan, Burger, Nils, Kula-Alwar, Duvaraka, Aksentijević, Dunja, Bridges, Hannah R., Prag, Hiran A., Grba, Daniel N., Viscomi, Carlo, James, Andrew M., Mottahedin, Amin, Krieg, Thomas, Murphy, Michael P., Hirst, Judy
Published in Nature communications (29.01.2021)
Published in Nature communications (29.01.2021)
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Journal Article
Cardiac metabolism as a driver and therapeutic target of myocardial infarction
Zuurbier, Coert J., Bertrand, Luc, Beauloye, Christoph R., Andreadou, Ioanna, Ruiz‐Meana, Marisol, Jespersen, Nichlas R., Kula‐Alwar, Duvaraka, Prag, Hiran A., Eric Botker, Hans, Dambrova, Maija, Montessuit, Christophe, Kaambre, Tuuli, Liepinsh, Edgars, Brookes, Paul S., Krieg, Thomas
Published in Journal of cellular and molecular medicine (01.06.2020)
Published in Journal of cellular and molecular medicine (01.06.2020)
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Journal Article
Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
Ryan, Dylan Gerard, Yang, Ming, Prag, Hiran A, Blanco, Giovanny Rodriguez, Nikitopoulou, Efterpi, Segarra-Mondejar, Marc, Powell, Christopher A, Young, Tim, Burger, Nils, Miljkovic, Jan Lj, Minczuk, Michal, Murphy, Michael P, von Kriegsheim, Alex, Frezza, Christian
Published in eLife (23.12.2021)
Published in eLife (23.12.2021)
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Journal Article
MitoNeoD: A Mitochondria-Targeted Superoxide Probe
Shchepinova, Maria M., Cairns, Andrew G., Prime, Tracy A., Logan, Angela, James, Andrew M., Hall, Andrew R., Vidoni, Sara, Arndt, Sabine, Caldwell, Stuart T., Prag, Hiran A., Pell, Victoria R., Krieg, Thomas, Mulvey, John F., Yadav, Pooja, Cobley, James N., Bright, Thomas P., Senn, Hans M., Anderson, Robert F., Murphy, Michael P., Hartley, Richard C.
Published in Cell chemical biology (19.10.2017)
Published in Cell chemical biology (19.10.2017)
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Journal Article
Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles
Faulkes, Chris G., Eykyn, Thomas R., Miljkovic, Jan Lj, Gilbert, James D., Charles, Rebecca L., Prag, Hiran A., Patel, Nikayla, Hart, Daniel W., Murphy, Michael P., Bennett, Nigel C., Aksentijevic, Dunja
Published in Nature communications (27.03.2024)
Published in Nature communications (27.03.2024)
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Journal Article
DJ-1: A promising therapeutic candidate for ischemia-reperfusion injury
De Lazzari, Federica, Prag, Hiran A., Gruszczyk, Anja V., Whitworth, Alexander J., Bisaglia, Marco
Published in Redox biology (01.05.2021)
Published in Redox biology (01.05.2021)
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Journal Article
Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo
Booty, Lee M, Gawel, Justyna M, Cvetko, Filip, Caldwell, Stuart T, Hall, Andrew R, Mulvey, John F, James, Andrew M, Hinchy, Elizabeth C, Prime, Tracy A, Arndt, Sabine, Beninca, Cristiane, Bright, Thomas P, Clatworthy, Menna R, Ferdinand, John R, Prag, Hiran A, Logan, Angela, Prudent, Julien, Krieg, Thomas, Hartley, Richard C, Murphy, Michael P
Published in Cell chemical biology (21.03.2019)
Published in Cell chemical biology (21.03.2019)
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Journal Article
Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury
Beach, Timothy E., Prag, Hiran A., Pala, Laura, Logan, Angela, Huang, Margaret M., Gruszczyk, Anja V., Martin, Jack L., Mahbubani, Krishnaa, Hamed, Mazin O., Hosgood, Sarah A., Nicholson, Michael L., James, Andrew M., Hartley, Richard C., Murphy, Michael P., Saeb-Parsy, Kourosh
Published in Redox biology (01.09.2020)
Published in Redox biology (01.09.2020)
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Journal Article
Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke
Mottahedin, Amin, Prag, Hiran A., Dannhorn, Andreas, Mair, Richard, Schmidt, Christina, Yang, Ming, Sorby-Adams, Annabel, Lee, Jordan J., Burger, Nils, Kulaveerasingam, Duvaraka, Huang, Margaret M., Pluchino, Stefano, Peruzzotti-Jametti, Luca, Goodwin, Richard, Frezza, Christian, Murphy, Michael P., Krieg, Thomas
Published in Redox biology (01.02.2023)
Published in Redox biology (01.02.2023)
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Journal Article
Corrigendum to “A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding” [Redox Biol. 72 (2024) 103161]
Sorby-Adams, Annabel, Prime, Tracy A., Miljkovic, Jan Lj, Prag, Hiran A., Krieg, Thomas, Murphy, Michael P.
Published in Redox biology (01.08.2024)
Published in Redox biology (01.08.2024)
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Journal Article
A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding
Sorby-Adams, Annabel, Prime, Tracy A., Miljkovic, Jan Lj, Prag, Hiran A., Krieg, Thomas, Murphy, Michael P.
Published in Redox biology (01.06.2024)
Published in Redox biology (01.06.2024)
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Journal Article
Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury
Miljkovic, Jan Lj, Burger, Nils, Gawel, Justyna M., Mulvey, John F., Norman, Abigail A.I., Nishimura, Takanori, Tsujihata, Yoshiyuki, Logan, Angela, Sauchanka, Olga, Caldwell, Stuart T., Morris, Jordan L., Prime, Tracy A., Warrington, Stefan, Prudent, Julien, Bates, Georgina R., Aksentijević, Dunja, Prag, Hiran A., James, Andrew M., Krieg, Thomas, Hartley, Richard C., Murphy, Michael P.
Published in Redox biology (01.09.2022)
Published in Redox biology (01.09.2022)
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Journal Article
Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury
Gruszczyk, Anja V., Casey, Alva M., James, Andrew M., Prag, Hiran A., Burger, Nils, Bates, Georgina R., Hall, Andrew R., Allen, Fay M., Krieg, Thomas, Saeb-Parsy, Kourosh, Murphy, Michael P.
Published in Redox biology (01.08.2022)
Published in Redox biology (01.08.2022)
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Journal Article
Has maternal sensitivity been comprehensively investigated in sub-Saharan Africa? A narrative scoping review
Prag, A, Donald, K A, Weldon, E, Halligan, S L, Stein, D J, Malcolm-Smith, S
Published in Acta neuropsychiatrica (24.03.2023)
Published in Acta neuropsychiatrica (24.03.2023)
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Journal Article
Targeting Succinate Metabolism in Ischemia/Reperfusion Injury
Kula-Alwar, Duvaraka, Prag, Hiran A, Krieg, Thomas
Published in Circulation (New York, N.Y.) (10.12.2019)
Published in Circulation (New York, N.Y.) (10.12.2019)
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Journal Article
Enhancing the Mitochondrial Uptake of Phosphonium Cations by Carboxylic Acid Incorporation
Pala, Laura, Senn, Hans M, Caldwell, Stuart T, Prime, Tracy A, Warrington, Stefan, Bright, Thomas P, Prag, Hiran A, Wilson, Claire, Murphy, Michael P, Hartley, Richard C
Published in Frontiers in chemistry (09.09.2020)
Published in Frontiers in chemistry (09.09.2020)
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Journal Article
Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport
Roca, Francisco J, Whitworth, Laura J, Prag, Hiran A, Murphy, Michael P, Ramakrishnan, Lalita
Published in Science (American Association for the Advancement of Science) (24.06.2022)
Published in Science (American Association for the Advancement of Science) (24.06.2022)
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Journal Article
Kinship between burials from Grave Circle B at Mycenae revealed by ancient DNA typing
Bouwman, Abigail S., Brown, Keri A., Prag, A. John N.W., Brown, Terence A.
Published in Journal of archaeological science (01.09.2008)
Published in Journal of archaeological science (01.09.2008)
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Journal Article
Preventing mitochondrial reverse electron transport as a strategy for cardioprotection
Prag, Hiran A., Murphy, Michael P., Krieg, Thomas
Published in Basic research in cardiology (28.08.2023)
Published in Basic research in cardiology (28.08.2023)
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Journal Article