Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy
Hall, James P, Poynton, Fergus E, Keane, Páraic M, Gurung, Sarah P, Brazier, John A, Cardin, David J, Winter, Graeme, Gunnlaugsson, Thorfinnur, Sazanovich, Igor V, Towrie, Michael, Cardin, Christine J, Kelly, John M, Quinn, Susan J
Published in Nature chemistry (01.12.2015)
Published in Nature chemistry (01.12.2015)
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Journal Article
The development of ruthenium(ii) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications
Poynton, Fergus E, Bright, Sandra A, Blasco, Salvador, Williams, D. Clive, Kelly, John M, Gunnlaugsson, Thorfinnur
Published in Chemical Society reviews (11.12.2017)
Published in Chemical Society reviews (11.12.2017)
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Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells
Cloonan, Suzanne M, Elmes, Robert B. P, Erby, MariaLuisa, Bright, Sandra A, Poynton, Fergus E, Nolan, Derek E, Quinn, Susan J, Gunnlaugsson, Thorfinnur, Williams, D. Clive
Published in Journal of medicinal chemistry (11.06.2015)
Published in Journal of medicinal chemistry (11.06.2015)
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Journal Article
Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics
Keane, Páraic M, Zehe, Clara, Poynton, Fergus E, Bright, Sandra A, Estayalo-Adrián, Sandra, Devereux, Stephen J, Donaldson, Paul M, Sazanovich, Igor V, Towrie, Michael, Botchway, Stanley W, Cardin, Christine J, Williams, D. Clive, Gunnlaugsson, Thorfinnur, Long, Conor, Kelly, John M, Quinn, Susan J
Published in Physical chemistry chemical physics : PCCP (18.11.2022)
Published in Physical chemistry chemical physics : PCCP (18.11.2022)
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Journal Article
Correction: Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics
Keane, Páraic M, Zehe, Clara, Poynton, Fergus E, Bright, Sandra A, Estayalo-Adrián, Sandra, Devereux, Stephen J, Donaldson, Paul M, Sazanovich, Igor V, Towrie, Michael, Botchway, Stanley W, Cardin, Christine J, Williams, D. Clive, Gunnlaugsson, Thorfinnur, Long, Conor, Kelly, John M, Quinn, Susan J
Published in Physical chemistry chemical physics : PCCP (30.08.2023)
Published in Physical chemistry chemical physics : PCCP (30.08.2023)
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Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides
Keane, Páraic M, O'Sullivan, Kyra, Poynton, Fergus E, Poulsen, Bjørn C, Sazanovich, Igor V, Towrie, Michael, Cardin, Christine J, Sun, Xue-Zhong, George, Michael W, Gunnlaugsson, Thorfinnur, Quinn, Susan J, Kelly, John M
Published in Chemical science (Cambridge) (19.08.2020)
Published in Chemical science (Cambridge) (19.08.2020)
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Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)(dppz)] light-switch compound in solution and when bound to DNA
Poynton, Fergus E, Hall, James P, Keane, Páraic M, Schwarz, Christine, Sazanovich, Igor V, Towrie, Michael, Gunnlaugsson, Thorfinnur, Cardin, Christine J, Cardin, David J, Quinn, Susan J, Long, Conor, Kelly, John M
Published in Chemical science (Cambridge) (01.01.2016)
Published in Chemical science (Cambridge) (01.01.2016)
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Journal Article
Caught in the Loop: Binding of the [Ru(phen)2(dppz)]2+ Light‐Switch Compound to Quadruplex DNA in Solution Informed by Time‐Resolved Infrared Spectroscopy
Devereux, Stephen J., Poynton, Fergus E., Baptista, Frederico R., Gunnlaugsson, Thorfinnur, Cardin, Christine J., Sazanovich, Igor V., Towrie, Michael, Kelly, John M., Quinn, Susan J.
Published in Chemistry : a European journal (18.12.2020)
Published in Chemistry : a European journal (18.12.2020)
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Journal Article
Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(II)-polypyridyl conjugates
Ryan, Gary J, Poynton, Fergus E, Elmes, Robert B P, Erby, Marialuisa, Williams, D Clive, Quinn, Susan J, Gunnlaugsson, Thorfinnur
Published in Dalton transactions : an international journal of inorganic chemistry (07.10.2015)
Published in Dalton transactions : an international journal of inorganic chemistry (07.10.2015)
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Journal Article
Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1,8-naphthalimide derived Troger's bases
Murphy, Samantha, Bright, Sandra A., Poynton, Fergus E., McCabe, Thomas, Kitchen, Jonathan A., Veale, Emma B., Williams, D. Clive, Gunnlaugsson, Thorfinnur
Published in Organic & biomolecular chemistry (14.09.2014)
Published in Organic & biomolecular chemistry (14.09.2014)
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Journal Article
Inosine Can Increase DNA's Susceptibility to Photo-oxidation by a Ru II Complex due to Structural Change in the Minor Groove
Keane, Páraic M, Hall, James P, Poynton, Fergus E, Poulsen, Bjørn C, Gurung, Sarah P, Clark, Ian P, Sazanovich, Igor V, Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J, Cardin, Christine J, Kelly, John M
Published in Chemistry : a European journal (01.08.2017)
Published in Chemistry : a European journal (01.08.2017)
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Journal Article
Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex
Keane, Páraic M., Poynton, Fergus E., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J., Cardin, Christine J., Kelly, John M.
Published in Angewandte Chemie (International ed.) (13.07.2015)
Published in Angewandte Chemie (International ed.) (13.07.2015)
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Journal Article
Enantiomeric Conformation Controls Rate and Yield of Photoinduced Electron Transfer in DNA Sensitized by Ru(II) Dipyridophenazine Complexes
Keane, Páraic M, Poynton, Fergus E, Hall, James P, Clark, Ian P, Sazanovich, Igor V, Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J, Cardin, Christine J, Kelly, John M
Published in The journal of physical chemistry letters (19.02.2015)
Published in The journal of physical chemistry letters (19.02.2015)
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Journal Article
Tracking the cellular uptake and phototoxicity of Ru()-polypyridyl-1,8-naphthalimide Tröger's base conjugates
Bright, Sandra A, Erby, MariaLuisa, Poynton, Fergus E, Monteyne, Daniel, Pérez-Morga, David, Gunnlaugsson, Thorfinnur, Williams, D. Clive, Elmes, Robert B. P
Published in RSC chemical biology (03.04.2024)
Published in RSC chemical biology (03.04.2024)
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Journal Article
Monitoring guanine photo-oxidation by enantiomerically resolved Ru(ii) dipyridophenazine complexes using inosine-substituted oligonucleotides
Keane, Páraic M, Poynton, Fergus E, Hall, James P, Clark, Ian P, Sazanovich, Igor V, Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J, Cardin, Christine J, Kelly, John M
Published in Faraday discussions (01.01.2015)
Published in Faraday discussions (01.01.2015)
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Journal Article
Frontispiece: Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex
Keane, Páraic M., Poynton, Fergus E., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J., Cardin, Christine J., Kelly, John M.
Published in Angewandte Chemie (International ed.) (13.07.2015)
Published in Angewandte Chemie (International ed.) (13.07.2015)
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Journal Article
Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen) 2 (dppz)] 2+ light-switch compound in solution and when bound to DNA
Poynton, Fergus E, Hall, James P, Keane, Páraic M, Schwarz, Christine, Sazanovich, Igor V, Towrie, Michael, Gunnlaugsson, Thorfinnur, Cardin, Christine J, Cardin, David J, Quinn, Susan J, Long, Conor, Kelly, John M
Published in Chemical science (Cambridge) (01.05.2016)
Published in Chemical science (Cambridge) (01.05.2016)
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Journal Article
Frontispiz: Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex
Keane, Páraic M., Poynton, Fergus E., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J., Cardin, Christine J., Kelly, John M.
Published in Angewandte Chemie (13.07.2015)
Published in Angewandte Chemie (13.07.2015)
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Journal Article
Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex
Keane, Páraic M., Poynton, Fergus E., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J., Cardin, Christine J., Kelly, John M.
Published in Angewandte Chemie (13.07.2015)
Published in Angewandte Chemie (13.07.2015)
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Journal Article
Inosine Can Increase DNA′s Susceptibility to Photo‐oxidation by a RuII Complex due to Structural Change in the Minor Groove
Keane, Páraic M., Hall, James P., Poynton, Fergus E., Poulsen, Bjørn C., Gurung, Sarah P., Clark, Ian P., Sazanovich, Igor V., Towrie, Michael, Gunnlaugsson, Thorfinnur, Quinn, Susan J., Cardin, Christine J., Kelly, John M.
Published in Chemistry : a European journal (01.08.2017)
Published in Chemistry : a European journal (01.08.2017)
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Journal Article