From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)
Cheng, Yuan, Judd, Ted C, Bartberger, Michael D, Brown, James, Chen, Kui, Fremeau, Robert T, Hickman, Dean, Hitchcock, Stephen A, Jordan, Brad, Li, Vivian, Lopez, Patricia, Louie, Steven W, Luo, Yi, Michelsen, Klaus, Nixey, Thomas, Powers, Timothy S, Rattan, Claire, Sickmier, E. Allen, St. Jean, David J, Wahl, Robert C, Wen, Paul H, Wood, Stephen
Published in Journal of medicinal chemistry (25.08.2011)
Published in Journal of medicinal chemistry (25.08.2011)
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Journal Article
Discovery and Evaluation of a Non-Zn Chelating, Selective Matrix Metalloproteinase 13 (MMP-13) Inhibitor for Potential Intra-articular Treatment of Osteoarthritis
Gege, Christian, Bao, Bagna, Bluhm, Harald, Boer, Jürgen, Gallagher, Brian M, Korniski, Brian, Powers, Timothy S, Steeneck, Christoph, Taveras, Arthur G, Baragi, Vijaykumar M
Published in Journal of medicinal chemistry (26.01.2012)
Published in Journal of medicinal chemistry (26.01.2012)
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Journal Article
Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer’s disease
Chen, Jian Jeffrey, Liu, Qingyian, Yuan, Chester, Gore, Vijay, Lopez, Patricia, Ma, Vu, Amegadzie, Albert, Qian, Wenyuan, Judd, Ted C., Minatti, Ana E., Brown, James, Cheng, Yuan, Xue, May, Zhong, Wenge, Dineen, Thomas A., Epstein, Oleg, Human, Jason, Kreiman, Charles, Marx, Isaac, Weiss, Matthew M., Hitchcock, Stephen A., Powers, Timothy S., Chen, Kui, Wen, Paul H., Whittington, Douglas A., Cheng, Alan C., Bartberger, Michael D., Hickman, Dean, Werner, Jonathan A., Vargas, Hugo M., Everds, Nancy E., Vonderfecht, Steven L., Dunn, Robert T., Wood, Stephen, Fremeau, Robert T., White, Ryan D., Patel, Vinod F.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Journal Article
An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities
Cheng, Yuan, Brown, James, Judd, Ted C, Lopez, Patricia, Qian, Wenyuan, Powers, Timothy S, Chen, Jian Jeffrey, Bartberger, Michael D, Chen, Kui, Dunn, Robert T, Epstein, Oleg, Fremeau, Robert T, Harried, Scott, Hickman, Dean, Hitchcock, Stephen A, Luo, Yi, Minatti, Ana Elena, Patel, Vinod F, Vargas, Hugo M, Wahl, Robert C, Weiss, Matthew M, Wen, Paul H, White, Ryan D, Whittington, Douglas A, Zheng, Xiao Mei, Wood, Stephen
Published in ACS medicinal chemistry letters (12.02.2015)
Published in ACS medicinal chemistry letters (12.02.2015)
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Journal Article
Preaccession fitness and body composition as predictors of attrition in U.S. Army recruits
Niebuhr, David W, Scott, Christine T, Li, Yuanzhang, Bedno, Sheryl A, Han, Weiwei, Powers, Timothy E
Published in Military medicine (01.07.2009)
Published in Military medicine (01.07.2009)
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Journal Article
Assessment of recruit motivation and strength study: preaccession physical fitness assessment predicts early attrition
Niebuhr, David W, Scott, Christine T, Powers, Timothy E, Li, Yuanzhang, Han, Weiwei, Millikan, Amy M, Krauss, Margot R
Published in Military medicine (01.06.2008)
Published in Military medicine (01.06.2008)
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Journal Article
Combinatorial Materials Science and Catalysis
Jandeleit, Bernd, Schaefer, Dieter J., Powers, Timothy S., Turner, Howard W., Weinberg, W. Henry
Published in Angewandte Chemie International Edition (03.09.1999)
Published in Angewandte Chemie International Edition (03.09.1999)
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Journal Article
Attrition of military enlistees with a medical waiver for chronic headache, 1995-2000
Jankosky, Christopher, Niebuhr, David W, Powers, Timothy E, Krauss, Margot R
Published in Military medicine (01.12.2006)
Published in Military medicine (01.12.2006)
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Journal Article
Attrition of U.S. military enlistees with waivers for hearing deficiency, 1995-2004
Niebuhr, David W, Li, Yuanzhang, Powers, Timothy E, Krauss, Margot R, Chandler, David, Helfer, Thomas
Published in Military medicine (01.01.2007)
Published in Military medicine (01.01.2007)
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Journal Article
Adjacent segment disc pressures following two-level cervical disc replacement versus simulated anterior cervical fusion
Laxer, Eric B, Darden, Bruce V, Murrey, Daniel B, Milam, R Alden, Rhyne, Alfred L, Claytor, Brian, Nussman, Donna S, Powers, Timothy W, Davies, Matthew A, Bryant, S Chad, Larsen, Scott P, Bhatt, Meghal, Brodziak, John, Polic, Jelena
Published in Studies in health technology and informatics (2006)
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Published in Studies in health technology and informatics (2006)
Journal Article
Attrition of military enlistees with a medical waiver for myopia, 1999-2001
Otto, William C, Niebuhr, David W, Powers, Timothy E, Krauss, Margot R, McVeigh, Francis L, Tarbett, Aaron K
Published in Military medicine (01.11.2006)
Published in Military medicine (01.11.2006)
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Journal Article
Asymmetric Exo-Selective Diels−Alder Reactions by Steric Attenuation of Secondary Orbital Interactions
Powers, Timothy S, Jiang, Weiqin, Su, Jing, Wulff, William D, Waltermire, Beth E, Rheingold, Arnold L
Published in Journal of the American Chemical Society (09.07.1997)
Published in Journal of the American Chemical Society (09.07.1997)
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Journal Article
BERYLLIUM AND LUNG CANCER: A REANALYSIS OF A NIOSH COHORT MORTALITY STUDY
Levy, Paul S., Roth, H. Daniel, Hwang, Peggy May T., Powers, Timothy E.
Published in Inhalation toxicology (01.10.2002)
Published in Inhalation toxicology (01.10.2002)
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Journal Article
The preparation of imidazolidinone and oxazolidinone chelated carbene complexes
Powers, Timothy S, Wulff, William D, Quinn, John, Shi, Yan, Jiang, Weiqin, Hsung, Richard, Parisi, Mark, Rahm, Annette, Wu Jiang, Xiao, Yap, Glenn P.A, Rheingold, Arnold L
Published in Journal of Organometallic Chemistry (01.01.2001)
Published in Journal of Organometallic Chemistry (01.01.2001)
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Book Review
Journal Article
Exo-selective Diels-Alder reactions of aminocarbene complexes
Anderson, Benjamin A, Wulff, William D, Powers, Timothy S, Tribbitt, Sandra, Rheingold, Arnold L
Published in Journal of the American Chemical Society (01.12.1992)
Published in Journal of the American Chemical Society (01.12.1992)
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Journal Article