Discovery of Potent, Selective, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase
Greco, Michael N, Hawkins, Michael J, Powell, Eugene T, Almond, Harold R, de Garavilla, Lawrence, Hall, Jeffrey, Minor, Lisa K, Wang, Yuanping, Corcoran, Thomas W, Di Cera, Enrico, Cantwell, Angelene M, Savvides, Savvas N, Damiano, Bruce P, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (19.04.2007)
Published in Journal of medicinal chemistry (19.04.2007)
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Journal Article
Facile Dephosphonylation of β-Ketophosphonic Acids: Mechanistic Studies
Hawkins, Michael J, Powell, Eugene T, Leo, Gregory C, Gauthier, Diane A, Greco, Michael N, Maryanoff, Bruce
Published in Organic letters (03.08.2006)
Published in Organic letters (03.08.2006)
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Journal Article
Nonpeptide Inhibitors of Cathepsin G: Optimization of a Novel β-Ketophosphonic Acid Lead by Structure-Based Drug Design
Greco, Michael N, Hawkins, Michael J, Powell, Eugene T, Almond, Harold R, Corcoran, Thomas W, de Garavilla, Lawrence, Kauffman, Jack A, Recacha, Rosario, Chattopadhyay, Debashish, Andrade-Gordon, Patricia, Maryanoff, Bruce E
Published in Journal of the American Chemical Society (17.04.2002)
Published in Journal of the American Chemical Society (17.04.2002)
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Journal Article
Orally Active Benzamide Antipsychotic Agents with Affinity for Dopamine D2, Serotonin 5-HT1A, and Adrenergic α1 Receptors
Reitz, Allen B, Baxter, Ellen W, Codd, Ellen E, Davis, Coralie B, Jordan, Alfonzo D, Maryanoff, Bruce E, Maryanoff, Cynthia A, McDonnell, Mark E, Powell, Eugene T, Renzi, Michael J, Schott, Mary R, Scott, Malcolm K, Shank, Richard P, Vaught, Jeffry L
Published in Journal of medicinal chemistry (04.06.1998)
Published in Journal of medicinal chemistry (04.06.1998)
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Journal Article
Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid
Greco, Michael N, Hageman, William E, Powell, Eugene T, Tighe, Joseph J, Persico, Francis J
Published in Journal of medicinal chemistry (01.08.1992)
Published in Journal of medicinal chemistry (01.08.1992)
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Journal Article
Novel thrombin inhibitors that are based on a macrocyclic tripeptide motif
Greco, Michael N., Powell, Eugene T., Hecker, Leonard R., Andrade-Gordon, Patricia, Kauffman, Jack A., Lewis, Joan M., Ganesh, Venkatapathy, Tulinsky, Alexander, Maryanoff, Bruce E.
Published in Bioorganic & medicinal chemistry letters (17.12.1996)
Published in Bioorganic & medicinal chemistry letters (17.12.1996)
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Journal Article
Orally Active Benzamide Antipsychotic Agents with Affinity for Dopamine D 2 , Serotonin 5-HT 1A , and Adrenergic α 1 Receptors
Reitz, Allen B., Baxter, Ellen W., Codd, Ellen E., Davis, Coralie B., Jordan, Alfonzo D., Maryanoff, Bruce E., Maryanoff, Cynthia A., McDonnell, Mark E., Powell, Eugene T., Renzi, Michael J., Schott, Mary R., Scott, Malcolm K., Shank, Richard P., Vaught, Jeffry L.
Published in Journal of medicinal chemistry (01.06.1998)
Published in Journal of medicinal chemistry (01.06.1998)
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Journal Article
Novel inhibitors of chymase
GRECO MICHAEL N, GARAVILLA LAWRENCE DE, POWELL EUGENE, MARYANOFF BRUCE E, HAWKINS MICHAEL J
Year of Publication 24.04.2013
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Year of Publication 24.04.2013
Patent
Novel inhibitors of chymase
GRECO MICHAEL N, GARAVILLA LAWRENCE DE, POWELL EUGENE, MARYANOFF BRUCE E, HAWKINS MICHAEL J
Year of Publication 20.10.2010
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Year of Publication 20.10.2010
Patent
Novel inhibitors of chymase
GRECO MICHAEL N, POWELL EUGENE, MARYANOFF BRUCE E, HAWKINS MICHAEL J, DE GARAVILLA LAWRENCE
Year of Publication 26.05.2010
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Year of Publication 26.05.2010
Patent
Novel phosphonic acid compounds as inhibitors of serine proteases
NILSEN CHRISTOPHER NORMAN, SORGI KIRK LEONARD, QIAN YUN, POWELL EUGENE, WALKER DONALD GILMORE, DE GARAVILLA LAWRENCE
Year of Publication 08.04.2009
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Year of Publication 08.04.2009
Patent
Novel inhibitors of chymase
HAWKINS, MICHAEL J, POWELL, EUGENE, DE GARAVILLA, LAWRENCE, GRECO, MICHAEL N, MARYANOFF, BRUCE E
Year of Publication 16.12.2005
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Year of Publication 16.12.2005
Patent