A Pd(0)-Mediated Indole (Macro)cyclization Reaction
Breazzano, Steven P, Poudel, Yam B, Boger, Dale L
Published in Journal of the American Chemical Society (30.01.2013)
Published in Journal of the American Chemical Society (30.01.2013)
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Journal Article
Universal Affinity Capture Liquid Chromatography-Mass Spectrometry Assay for Evaluation of Biotransformation of Site-Specific Antibody Drug Conjugates in Preclinical Studies
Kotapati, Srikanth, Passmore, David, Yamazoe, Sayumi, Sanku, Rajesh Kishore Kumar, Cong, Qiang, Poudel, Yam B, Chowdari, Naidu S, Gangwar, Sanjeev, Rao, Chetana, Rangan, Vangipuram S, Cardarelli, Pina M, Deshpande, Shrikant, Strop, Pavel, Dollinger, Gavin, Rajpal, Arvind
Published in Analytical chemistry (Washington) (21.01.2020)
Published in Analytical chemistry (Washington) (21.01.2020)
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Journal Article
Chemical Modification of Linkers Provides Stable Linker–Payloads for the Generation of Antibody–Drug Conjugates
Poudel, Yam B, Chowdari, Naidu S, Cheng, Heng, Iwuagwu, Christiana I, King, H. Dalton, Kotapati, Srikanth, Passmore, David, Rampulla, Richard, Mathur, Arvind, Vite, Gregory, Gangwar, Sanjeev
Published in ACS medicinal chemistry letters (12.11.2020)
Published in ACS medicinal chemistry letters (12.11.2020)
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Journal Article
Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1
Keck, Gary E., Poudel, Yam B., Rudra, Arnab, Stephens, Jeffrey C., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Blumberg, Peter M.
Published in Angewandte Chemie International Edition (21.06.2010)
Published in Angewandte Chemie International Edition (21.06.2010)
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Journal Article
Total Synthesis of Bryostatin 1
Keck, Gary E, Poudel, Yam B, Cummins, Thomas J, Rudra, Arnab, Covel, Jonathan A
Published in Journal of the American Chemical Society (02.02.2011)
Published in Journal of the American Chemical Society (02.02.2011)
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Journal Article
Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity
KECK, Gary E, POUDEL, Yam B, RUDRA, Arnab, STEPHENS, Jeffrey C, KEDEI, Noemi, LEWIN, Nancy E, BLUMBERG, Peter M
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
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Journal Article
Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations
Nicolaou, K. C, Wang, Yanping, Lu, Min, Mandal, Debashis, Pattanayak, Manas R, Yu, Ruocheng, Shah, Akshay A, Chen, Jason S, Zhang, Hongjun, Crawford, James J, Pasunoori, Laxman, Poudel, Yam B, Chowdari, Naidu S, Pan, Chin, Nazeer, Ayesha, Gangwar, Sanjeev, Vite, Gregory, Pitsinos, Emmanuel N
Published in Journal of the American Chemical Society (06.07.2016)
Published in Journal of the American Chemical Society (06.07.2016)
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Journal Article
Design, synthesis and biological evaluation of phenol-linked uncialamycin antibody-drug conjugates
Poudel, Yam B., Rao, Chetana, Kotapati, Srikanth, Deshpande, Madhura, Thevanayagam, Lourdes, Pan, Chin, Cardarelli, Josephine, Chowdari, Naidu, Kaspady, Mahammed, Samikannu, Ramesh, Kuppusamy, Prakasam, Saravanakumar, Pon, Arunachalam, Pirama N., Deshpande, Shrikant, Rangan, Vangipuram, Rampulla, Richard, Mathur, Arvind, Vite, Gregory D., Gangwar, Sanjeev
Published in Bioorganic & medicinal chemistry letters (01.01.2020)
Published in Bioorganic & medicinal chemistry letters (01.01.2020)
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Journal Article
Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core
Kraft, Matthew B, Poudel, Yam B, Kedei, Noemi, Lewin, Nancy E, Peach, Megan L, Blumberg, Peter M, Keck, Gary E
Published in Journal of the American Chemical Society (24.09.2014)
Published in Journal of the American Chemical Society (24.09.2014)
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Journal Article
Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology
Poudel, Yam B., He, Liqi, Cox, Matthew, Zhang, Qian, Johnson, Walter L., Cong, Qiang, Cheng, Heng, Chowdari, Naidu S., Tarby, Christine, Donnell, Andrew F., Broekema, Matthais, O’Malley, Daniel P., Zhang, Yong, A. M. Subbaiah, Murugaiah, Kumar, Boda Vijay, Subramani, Lakshumanan, Wang, Bei, Li, Yi-Xin, Sivaprakasam, Prasanna, Critton, David, Mulligan, Dawn, Sandhu, Bhupindar, Xie, Chunshan, Ramakrishnan, Radha, Nagar, Jignesh, Dudhgaonkar, Shailesh, Oderinde, Martins S., Murtaza, Anwar, Schieven, Gary L., Mathur, Arvind, Gavai, Ashvinikumar V., Vite, Gregory, Gangwar, Sanjeev
Published in ACS medicinal chemistry letters (08.02.2024)
Published in ACS medicinal chemistry letters (08.02.2024)
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Journal Article
Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology
He, Liqi, Zhang, Meng Yao, Cox, Matthew, Zhang, Qian, Donnell, Andrew F., Zhang, Yong, Tarby, Christine, Gill, Patrice, Subbaiah, Murugaiah A. M., Ramar, Thangeswaran, Reddy, Maheswara, Puttapaka, Vijaya, Li, Yi-Xin, Sivaprakasam, Prasanna, Critton, David, Mulligan, Dawn, Xie, Chunshan, Ramakrishnan, Radha, Nagar, Jignesh, Dudhgaonkar, Shailesh, Murtaza, Anwar, Oderinde, Martins S., Schieven, Gary L., Mathur, Arvind, Gavai, Ashvinikumar V., Vite, Gregory, Gangwar, Sanjeev, Poudel, Yam B.
Published in ACS medicinal chemistry letters (08.02.2024)
Published in ACS medicinal chemistry letters (08.02.2024)
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Journal Article
Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters
Keck, Gary E, Poudel, Yam B, Welch, Dennie S, Kraft, Matthew B, Truong, Anh P, Stephens, Jeffrey C, Kedei, Noemi, Lewin, Nancy E, Blumberg, Peter M
Published in Organic letters (05.02.2009)
Published in Organic letters (05.02.2009)
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Journal Article
Biological Profile of the Less Lipophilic and Synthetically More Accessible Bryostatin 7 Closely Resembles That of Bryostatin 1
Kedei, Noemi, Lewin, Nancy E, Géczy, Tamás, Selezneva, Julia, Braun, Derek C, Chen, Jinqiu, Herrmann, Michelle A, Heldman, Madeleine R, Lim, Langston, Mannan, Poonam, Garfield, Susan H, Poudel, Yam B, Cummins, Thomas J, Rudra, Arnab, Blumberg, Peter M, Keck, Gary E
Published in ACS chemical biology (19.04.2013)
Published in ACS chemical biology (19.04.2013)
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Journal Article
Role of the C8gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity
Keck, Gary E., Poudel, Yam B., Rudra, Arnab, Stephens, Jeffrey C., Kedei, Noemi, Lewin, Nancy E., Blumberg, Peter M.
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
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Journal Article
면역자극제 톨-유사 수용체 7 (TLR7) 효능제로서의 6-아미노-7,9-디히드로-8H-퓨린-8-온 유도체
POUDEL YAM B, GANGWAR SANJEEV, SIVAPRAKASAM PRASANNA, POSY SHOSHANA L
Year of Publication 22.04.2020
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Year of Publication 22.04.2020
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