Search Results - "Pou, Sovitj" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo

Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo

by Pal, Anasuya C, Renard, Isaline, Singh, Pallavi, Vydyam, Pratap, Chiu, Joy E, Pou, Sovitj, Winter, Rolf W, Dodean, Rozalia, Frueh, Lisa, Nilsen, Aaron C, Riscoe, Michael K, Doggett, J Stone, Ben Mamoun, Choukri
Published in The Journal of infectious diseases (28.09.2022)

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Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages

by Ke, Hangjun, Ganesan, Suresh M, Dass, Swati, Morrisey, Joanne M, Pou, Sovitj, Nilsen, Aaron, Riscoe, Michael K, Mather, Michael W, Vaidya, Akhil B
Published in PloS one (09.04.2019)

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Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

by Lawres, Lauren A, Garg, Aprajita, Kumar, Vidya, Bruzual, Igor, Forquer, Isaac P, Renard, Isaline, Virji, Azan Z, Boulard, Pierre, Rodriguez, Eduardo X, Allen, Alexander J, Pou, Sovitj, Wegmann, Keith W, Winter, Rolf W, Nilsen, Aaron, Mao, Jialing, Preston, Douglas A, Belperron, Alexia A, Bockenstedt, Linda K, Hinrichs, David J, Riscoe, Michael K, Doggett, J Stone, Ben Mamoun, Choukri
Published in The Journal of experimental medicine (27.06.2016)

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Discovery, Synthesis, and Optimization of Antimalarial 4(1H)‑Quinolone-3-Diarylethers

Discovery, Synthesis, and Optimization of Antimalarial 4(1H)‑Quinolone-3-Diarylethers

by Nilsen, Aaron, Miley, Galen P, Forquer, Isaac P, Mather, Michael W, Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M, Stickles, Allison M, Ryan, Eileen, Kelly, Jane Xu, Doggett, J. Stone, White, Karen L, Hinrichs, David J, Winter, Rolf W, Charman, Susan A, Zakharov, Lev N, Bathurst, Ian, Burrows, Jeremy N, Vaidya, Akhil B, Riscoe, Michael K
Published in Journal of medicinal chemistry (08.05.2014)

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Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi

Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi

by Silva, Marta G, Bastos, Reginaldo G, Stone Doggett, J, Riscoe, Michael K, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A, Nilsen, Aaron, Suarez, Carlos E
Published in Parasites & vectors (03.12.2020)

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ELQ-331 as a prototype for extremely durable chemoprotection against malaria

ELQ-331 as a prototype for extremely durable chemoprotection against malaria

by Smilkstein, Martin J, Pou, Sovitj, Krollenbrock, Alina, Bleyle, Lisa A, Dodean, Rozalia A, Frueh, Lisa, Hinrichs, David J, Li, Yuexin, Martinson, Thomas, Munar, Myrna Y, Winter, Rolf W, Bruzual, Igor, Whiteside, Samantha, Nilsen, Aaron, Koop, Dennis R, Kelly, Jane X, Kappe, Stefan H I, Wilder, Brandon K, Riscoe, Michael K
Published in Malaria journal (27.08.2019)

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Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

by McConnell, Erin V, Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia A, Smilkstein, Martin J, Krollenbrock, Alina, Nilsen, Aaron, Zakharov, Lev N, Riscoe, Michael K, Doggett, J Stone
Published in ACS infectious diseases (09.11.2018)

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Sontochin as a Guide to the Development of Drugs against Chloroquine-Resistant Malaria

Sontochin as a Guide to the Development of Drugs against Chloroquine-Resistant Malaria

by POU, Sovitj, WINTER, Rolf W, NILSEN, Aaron, XU KELLY, Jane, YUEXIN LI, STONE DOGGETT, J, RISCOE, Erin W, WEGMANN, Keith W, HINRICHS, David J, RISCOE, Michael K
Published in Antimicrobial Agents and Chemotherapy (01.07.2012)

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Endochin-Like Quinolones Exhibit Promising Efficacy Against Neospora Caninum in vitro and in Experimentally Infected Pregnant Mice

Endochin-Like Quinolones Exhibit Promising Efficacy Against Neospora Caninum in vitro and in Experimentally Infected Pregnant Mice

by Anghel, Nicoleta, Balmer, Vreni, Müller, Joachim, Winzer, Pablo, Aguado-Martinez, Adriana, Roozbehani, Mona, Pou, Sovitj, Nilsen, Aaron, Riscoe, Michael, Doggett, J Stone, Hemphill, Andrew
Published in Frontiers in veterinary science (19.11.2018)

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Mechanism of Free-Radical Generation by Nitric Oxide Synthase

Mechanism of Free-Radical Generation by Nitric Oxide Synthase

by Rosen, Gerald M, Tsai, Pei, Pou, Sovitj
Published in Chemical reviews (01.04.2002)

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Mechanism of Superoxide Generation by Neuronal Nitric-oxide Synthase

Mechanism of Superoxide Generation by Neuronal Nitric-oxide Synthase

by Pou, S, Keaton, L, Surichamorn, W, Rosen, G M
Published in The Journal of biological chemistry (02.04.1999)

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The Role of Tetrahydrobiopterin in the Regulation of Neuronal Nitric-oxide Synthase-generated Superoxide

The Role of Tetrahydrobiopterin in the Regulation of Neuronal Nitric-oxide Synthase-generated Superoxide

by Rosen, Gerald M, Tsai, Pei, Weaver, John, Porasuphatana, Supatra, Roman, Linda J, Starkov, Anatoly A, Fiskum, Gary, Pou, Sovitj
Published in The Journal of biological chemistry (25.10.2002)

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Esters of 5-Carboxyl-5-methyl-1-pyrroline N-Oxide: A Family of Spin Traps for Superoxide

Esters of 5-Carboxyl-5-methyl-1-pyrroline N-Oxide: A Family of Spin Traps for Superoxide

by Tsai, Pei, Ichikawa, Kazuhiro, Mailer, Colin, Pou, Sovitj, Halpern, Howard J, Robinson, Bruce H, Nielsen, Robert, Rosen, Gerald M
Published in Journal of organic chemistry (03.10.2003)

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Influence of Conformation on the EPR Spectrum of 5,5-Dimethyl-1-hydroperoxy-1-pyrrolidinyloxyl: A Spin Trapped Adduct of Superoxide

Influence of Conformation on the EPR Spectrum of 5,5-Dimethyl-1-hydroperoxy-1-pyrrolidinyloxyl: A Spin Trapped Adduct of Superoxide

by Rosen, Gerald M, Beselman, Aleksandra, Tsai, Pei, Pou, Sovitj, Mailer, Colin, Ichikawa, Kazuhiro, Robinson, Bruce H, Nielsen, Robert, Halpern, Howard J, MacKerell, Alexander D
Published in Journal of organic chemistry (20.02.2004)

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Superoxide Dismutase versus Ferricytochrome C: Determining Rate Constants for the Spin Trapping of Superoxide by Cyclic Nitrones

Superoxide Dismutase versus Ferricytochrome C: Determining Rate Constants for the Spin Trapping of Superoxide by Cyclic Nitrones

by Weaver, John, Tsai, Pei, Pou, Sovitj, Rosen, Gerald M
Published in Journal of organic chemistry (26.11.2004)

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Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii

Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii

by Alday, P Holland, Bruzual, Igor, Nilsen, Aaron, Pou, Sovitj, Winter, Rolf, Ben Mamoun, Choukri, Riscoe, Michael K, Doggett, J Stone
Published in Antimicrobial agents and chemotherapy (01.02.2017)

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Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil

Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil

by van Schalkwyk, Donelly A, Riscoe, Michael K, Pou, Sovitj, Winter, Rolf W, Nilsen, Aaron, Duffey, Maëlle, Moon, Robert W, Sutherland, Colin J
Published in Antimicrobial agents and chemotherapy (21.04.2020)

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Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

by Doggett, J Stone, Schultz, Tracey, Miller, Alyssa J, Bruzual, Igor, Pou, Sovitj, Winter, Rolf, Dodean, Rozalia, Zakharov, Lev N, Nilsen, Aaron, Riscoe, Michael K, Carruthers, Vern B
Published in Antimicrobial agents and chemotherapy (20.08.2020)

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Long-acting intramuscular injections of ELQ-331, an antimalarial agent

Long-acting intramuscular injections of ELQ-331, an antimalarial agent

by Karunakaran, Dipu, Mutyam, Shravan K., Fu, Melody, Chen, Jiaming, Pham, Kim Hue Nicky, Pou, Sovitj, Winter, Rolf W., Nilsen, Aaron, Dodean, Rozalia A., Smilkstein, Martin J., Riscoe, Michael K., Shankar, Gita
Published in European journal of pharmaceutical sciences (01.07.2024)

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Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems

Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems

by Potharaju, Suresh, Mutyam, Shravan Kumar, Liu, Mingtao, Green, Carol, Frueh, Lisa, Nilsen, Aaron, Pou, Sovitj, Winter, Rolf, Riscoe, Michael K, Shankar, Gita
Published in Pharmaceutical development and technology (27.05.2020)

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