Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria
Buckley, Catherine M., Pots, Henderikus, Gueho, Aurelie, Vines, James H., Munn, Christopher J., Phillips, Ben A., Gilsbach, Bernd, Traynor, David, Nikolaev, Anton, Soldati, Thierry, Parnell, Andrew J., Kortholt, Arjan, King, Jason S.
Published in Current biology (03.08.2020)
Published in Current biology (03.08.2020)
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Journal Article
GPCR-controlled membrane recruitment of negative regulator C2GAP1 locally inhibits Ras signaling for adaptation and long-range chemotaxis
Xu, Xuehua, Wen, Xi, Veltman, Douwe M., Keizer-Gunnink, Ineke, Pots, Henderikus, Kortholt, Arjan, Jin, Tian
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.11.2017)
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Journal Article
Forty-five years of cGMP research in Dictyostelium : understanding the regulation and function of the cGMP pathway for cell movement and chemotaxis
van Haastert, Peter J M, Keizer-Gunnink, Ineke, Pots, Henderikus, Ortiz-Mateos, Claudia, Veltman, Douwe, van Egmond, Wouter, Kortholt, Arjan
Published in Molecular biology of the cell (01.10.2021)
Published in Molecular biology of the cell (01.10.2021)
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Characterization of Lipopolysaccharide Effects on LRRK2 Signaling in RAW Macrophages
Oun, Asmaa, Hoeksema, Emmy, Soliman, Ahmed, Brouwer, Famke, García-Reyes, Fabiola, Pots, Henderikus, Trombetta-Lima, Marina, Kortholt, Arjan, Dolga, Amalia M
Published in International journal of molecular sciences (13.01.2023)
Published in International journal of molecular sciences (13.01.2023)
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A homologue of the Parkinson's disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover
Deyaert, Egon, Wauters, Lina, Guaitoli, Giambattista, Konijnenberg, Albert, Leemans, Margaux, Terheyden, Susanne, Petrovic, Arsen, Gallardo, Rodrigo, Nederveen-Schippers, Laura M, Athanasopoulos, Panagiotis S, Pots, Henderikus, Van Haastert, Peter J M, Sobott, Frank, Gloeckner, Christian Johannes, Efremov, Rouslan, Kortholt, Arjan, Versées, Wim
Published in Nature communications (18.10.2017)
Published in Nature communications (18.10.2017)
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Journal Article
C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis
Xu, Xuehua, Pots, Henderikus, Gilsbach, Bernd K, Parsons, Dustin, Veltman, Douwe M, Ramachandra, Sharmila G, Li, Haoran, Kortholt, Arjan, Jin, Tian
Published in Frontiers in immunology (29.11.2022)
Published in Frontiers in immunology (29.11.2022)
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Journal Article
The small GTPases Ras and Rap1 bind to and control TORC2 activity
Khanna, Ankita, Lotfi, Pouya, Chavan, Anita J, Montaño, Nieves M, Bolourani, Parvin, Weeks, Gerald, Shen, Zhouxin, Briggs, Steven P, Pots, Henderikus, Van Haastert, Peter J M, Kortholt, Arjan, Charest, Pascale G
Published in Scientific reports (13.05.2016)
Published in Scientific reports (13.05.2016)
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Membrane Targeting of C2GAP1 Enables Dictyostelium discoideum to Sense Chemoattractant Gradient at a Higher Concentration Range
Xu, Xuehua, Bhimani, Smit, Pots, Henderikus, Wen, Xi, Jeon, Taeck J, Kortholt, Arjan, Jin, Tian
Published in Frontiers in cell and developmental biology (30.07.2021)
Published in Frontiers in cell and developmental biology (30.07.2021)
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Journal Article
Direct Interaction between TalinB and Rap1 is necessary for adhesion of Dictyostelium cells
Plak, Katarzyna, Pots, Henderikus, Van Haastert, Peter J M, Kortholt, Arjan
Published in BMC cell biology (07.01.2016)
Published in BMC cell biology (07.01.2016)
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Conformational heterogeneity of the Roc domains in C. tepidum Roc-COR and implications for human LRRK2 Parkinson mutations
Rudi, Katharina, Ho, Franz Y, Gilsbach, Bernd K, Pots, Henderikus, Wittinghofer, Alfred, Kortholt, Arjan, Klare, Johann P
Published in Bioscience reports (01.10.2015)
Published in Bioscience reports (01.10.2015)
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Journal Article
Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria
Buckley, Catherine M, Pots, Henderikus, Gueho, Aurelie, Phillips, Ben A, Gilsbach, Bernd, Traynor, David, Nikolaev, Anton, Soldati, Thierry, Parnell, Andrew J, Kortholt, Arjan, King, Jason S
Published in bioRxiv (17.10.2019)
Published in bioRxiv (17.10.2019)
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