SARS-CoV-2-specific CD4 + and CD8 + T cell responses can originate from cross-reactive CMV-specific T cells
Pothast, Cilia R, Dijkland, Romy C, Thaler, Melissa, Hagedoorn, Renate S, Kester, Michel G D, Wouters, Anne K, Hiemstra, Pieter S, van Hemert, Martijn J, Gras, Stephanie, Falkenburg, J H Frederik, Heemskerk, Mirjam H M
Published in eLife (21.11.2022)
Published in eLife (21.11.2022)
Get full text
Journal Article
Convalescent Plasma in a Patient with Protracted COVID-19 and Secondary Hypogammaglobulinemia Due to Chronic Lymphocytic Leukemia: Buying Time to Develop Immunity?
Hanssen, Jaap, Stienstra, Johan, Boers, Stefan, Pothast, Cilia, Zaaijer, Hans, Tjon, Jennifer, Heemskerk, Mirjam, Feltkamp, Mariet, Arend, Sandra
Published in Infectious disease reports (27.09.2021)
Published in Infectious disease reports (27.09.2021)
Get full text
Journal Article
Simultaneous Deletion of Endogenous TCRαβ for TCR Gene Therapy Creates an Improved and Safe Cellular Therapeutic
Morton, Laura T., Reijmers, Rogier M., Wouters, Anne K., Kweekel, Christiaan, Remst, Dennis F.G., Pothast, Cilia R., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Published in Molecular therapy (08.01.2020)
Published in Molecular therapy (08.01.2020)
Get full text
Journal Article
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19
Roukens, Anna H. E., Pothast, Cilia R., König, Marion, Huisman, Wesley, Dalebout, Tim, Tak, Tamar, Azimi, Shohreh, Kruize, Yvonne, Hagedoorn, Renate S., Zlei, Mihaela, Staal, Frank J. T., de Bie, Fenna J., van Dongen, Jacques J. M., Arbous, Sesmu M., Zhang, Jaimie L. H., Verheij, Maaike, Prins, Corine, van der Does, Anne M., Hiemstra, Pieter S., de Vries, Jutte J. C., Janse, Jacqueline J., Roestenberg, Meta, Myeni, Sebenzile K., Kikkert, Marjolein, Yazdanbakhsh, Maria, Heemskerk, Mirjam H. M., Smits, Hermelijn H., Jochems, Simon P.
Published in Nature immunology (01.01.2022)
Published in Nature immunology (01.01.2022)
Get full text
Journal Article
Human T cells recognize HLA-DP-bound peptides in two orientations
Klobuch, Sebastian, Lim, Jia Jia, van Balen, Peter, Kester, Michel G D, de Klerk, Wendy, de Ru, Arnoud H, Pothast, Cilia R, Jedema, Inge, Drijfhout, Jan W, Rossjohn, Jamie, Reid, Hugh H, van Veelen, Peter A, Falkenburg, J H Frederik, Heemskerk, Mirjam H M
Published in Proceedings of the National Academy of Sciences - PNAS (06.12.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (06.12.2022)
Get full text
Journal Article
Intradermal delivery of the third dose of the mRNA-1273 SARS-CoV-2 vaccine: safety and immunogenicity of a fractional booster dose
Roozen, Geert V.T., Prins, Manon L.M., Prins, Corine, Janse, Jacqueline J., de Gruyter, Heidi L.M., Pothast, Cilia R., Huisman, Wesley, Koopman, Jan Pieter R., Lamers, Olivia A.C., Kuijer, Marjan, Myeni, Sebenzile K., van Binnendijk, Rob S., Hartog, Gerco den, Heemskerk, Mirjam H.M., Jochems, Simon P., Feltkamp, Mariet C.W., Kikkert, Marjolein, Rosendaal, Frits R., Roestenberg, Meta, Visser, Leo G., Roukens, Anna H.E.
Published in Clinical microbiology and infection (01.07.2024)
Published in Clinical microbiology and infection (01.07.2024)
Get full text
Journal Article
Increased CD8 T‐cell immunity after COVID‐19 vaccination in lymphoid malignancy patients lacking adequate humoral response: An immune compensation mechanism?
Boerenkamp, Lara S., Pothast, Cilia R., Dijkland, Romy C., Dijk, Kayleigh, Gorkom, Gwendolyn N. Y., Loo, Inge H. M., Wieten, Lotte, Halkes, Constantijn J. M., Heemskerk, Mirjam H. M., Van Elssen, Catharina H. M. J.
Published in American journal of hematology (01.12.2022)
Published in American journal of hematology (01.12.2022)
Get full text
Journal Article
Immune Determinants of Viral Clearance in Hospitalised COVID-19 Patients: Reduced Circulating Naïve CD4+ T Cell Counts Correspond with Delayed Viral Clearance
Zlei, Mihaela, Sidorov, Igor A, Joosten, Simone A, Heemskerk, Mirjam H M, Myeni, Sebenzile K, Pothast, Cilia R, de Brouwer, Caroline S, Boomaars-van der Zanden, A Linda, van Meijgaarden, Krista E, Morales, Shessy T, Wessels, Els, Janse, Jacqueline J, Goeman, Jelle J, Cobbaert, Christa M, Kroes, Aloys C M, Cannegieter, Suzanne C, Roestenberg, Meta, Visser, Leonardus G, Kikkert, Marjolein, Feltkamp, Mariet C W, Arbous, Sesmu M, Staal, Frank J T, Ottenhoff, Tom H M, van Dongen, Jacques J M, Roukens, Anna H E, de Vries, Jutte J C, In Collaboration With Beat-Covid, In Collaboration With Lumc Covid
Published in Cells (Basel, Switzerland) (01.09.2022)
Published in Cells (Basel, Switzerland) (01.09.2022)
Get full text
Journal Article
P1536: SARS‐COV‐2 INFECTIONS IN PATIENTS WITH HAEMATOLOGIC MALIGNANCIES: EFFECT OF VACCINATION AND THE DEVELOPMENT OF HYBRID IMMUNITY
Haggenburg, Sabine, Reuvekamp, Tom, Hofsink, Quincy, Pothast, Cilia R., Dijkland, Romy C., Dijk, Kayleigh, Broers, Annoek E.C., Doesum, Jaap, Binnendijk, Rob S., Den Hartog, Gerco, Bhoekhan, Michel S., Haverkate, Nienke J.E., Vogels‐Nooijen, Sandra, Nijhof, Inger S., Heemskerk, Mirjam H.M., Rutten, Caroline E., Goorhuis, Abraham, Hazenberg, Mette D.
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
Get full text
Journal Article
Immunogenicity and reactogenicity of intradermal mRNA-1273 SARS-CoV-2 vaccination: a non-inferiority, randomized-controlled trial
Prins, Manon L. M., Roozen, Geert V. T., Pothast, Cilia. R., Huisman, Wesley, van Binnendijk, Rob, den Hartog, Gerco, Kuiper, Vincent P., Prins, Corine, Janse, Jacqueline J., Lamers, Olivia. A. C., Koopman, Jan Pieter R., Kruithof, Annelieke C., Kamerling, Ingrid M. C., Dijkland, Romy C., de Kroon, Alicia. C., Azimi, Shohreh, Feltkamp, Mariet C. W., Kuijer, Marjan, Jochems, Simon P., Heemskerk, Mirjam H. M., Rosendaal, Frits R., Roestenberg, Meta, Visser, Leo G., Roukens, Anna H. E.
Published in npj vaccines (02.01.2024)
Published in npj vaccines (02.01.2024)
Get full text
Journal Article
Sars-Cov-2-Specific CD4+ and CD8+ T Cell Responses Can Originate from Cross-Reactive CMV-Specific T Cells
Pothast, Cilia R., Dijkland, Romy C., Thaler, Melissa, Hagedoorn, Renate S., Kester, Michel G.D., Wouters, Anne K., Hiemstra, Pieter S., van Hemert, Martijn J., Gras, Stephanie, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article
Discordant Cellular and Humoral Responses to a 3-Dose COVID-19 mRNA Vaccination Schedule in Patients with Hematologic Malignancies
Pothast, Cilia R., Hofsink, Quincy, Haggenburg, Sabine, Michel, Bhoekhan S., Haverkate, Nienke J.E., Dijkland, Romy C., Van Dijk, Kayleigh, Falkenburg, Frederik J.H., Broers, Annoek E.C., van Doesum, Jaap, Van Binnendijk, Robert S., Den Hartog, Gerco, Burger, Judith A., Bouhuijs, Joey H., Lissenberg-Witte, Birgit I., Smits, Gaby P., Wouters, Dorine, van Leeuwen, Ester M.M., Bontkes, Hetty J., Kootstra, Neeltje A., Zweegman, Sonja, Kater, Arnon P., Groen, Kaz, van Meerten, Tom, Mutsaers, Pim G.N.J., Beaumont, Tim, Van Gils, Marit J., Goorhuis, Abraham, Hazenberg, Mette D., Nijhof, Inger S., Heemskerk, Mirjam H.M., Rutten, Caroline E.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article
Sickle Cell Disease Patients Mount Adequate Humoral but Reduced Cellular Responses to COVID-19 Vaccination
Pothast, Cilia R., Hofsink, Quincy, Haggenburg, Sabine, Bhoekhan, Michel, Haverkate, Nienke J.E., Dijkland, Romy C., van Dijk, Kayleigh, Falkenburg, Frederik J.H., Broers, Annoek E.C., van Doesum, Jaap, van Binnendijk, Robert S., den Hartog, Gerco, Burger, Judith A., Bouhuijs, Joey H., Lissenberg-Witte, Birgit I., Smits, Gaby P., Wouters, Dorine, van Leeuwen, Ester M.M., Bontkes, Hetty J., Kootstra, Neeltje A., Zweegman, Sonja, Kater, Arnon P., Groen, Kaz, van Meerten, Tom, Mutsaers, Pim G.N.J., Beaumont, Tim, van Gils, Marit J., Goorhuis, Abraham, Hazenberg, Mette D., Nijhof, Inger S., Heemskerk, Mirjam H.M., Rutten, Caroline E.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
Get full text
Journal Article
SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells
Pothast, Cilia R, Dijkland, Romy C, Thaler, Melissa, Hagedoorn, Renate S, Kester, Michel Gd, Wouters, Anne K, Hiemstra, Pieter S, Van Hemert, Martijn J, Gras, Stephanie, Jh Frederik Falkenburg, Heemskerk, Mirjam Hm
Published in bioRxiv (20.10.2022)
Published in bioRxiv (20.10.2022)
Get full text
Paper