Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure
Rasooly, Danielle, Peloso, Gina M., Pereira, Alexandre C., Dashti, Hesam, Giambartolomei, Claudia, Wheeler, Eleanor, Aung, Nay, Ferolito, Brian R., Pietzner, Maik, Farber-Eger, Eric H., Wells, Quinn Stanton, Kosik, Nicole M., Gaziano, Liam, Posner, Daniel C., Bento, A. Patrícia, Hui, Qin, Liu, Chang, Aragam, Krishna, Wang, Zeyuan, Charest, Brian, Huffman, Jennifer E., Wilson, Peter W. F., Phillips, Lawrence S., Whittaker, John, Munroe, Patricia B., Petersen, Steffen E., Cho, Kelly, Leach, Andrew R., Magariños, María Paula, Gaziano, John Michael, Langenberg, Claudia, Sun, Yan V., Joseph, Jacob, Casas, Juan P.
Published in Nature communications (10.07.2023)
Published in Nature communications (10.07.2023)
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Journal Article
Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program
Huang, Rose D L, Nguyen, Xuan-Mai T, Peloso, Gina M, Trinder, Mark, Posner, Daniel C, Aragam, Krishna G, Ho, Yuk-Lam, Lynch, Julie A, Damrauer, Scott M, Chang, Kyong-Mi, Tsao, Philip S, Natarajan, Pradeep, Assimes, Themistocles, Gaziano, J Michael, Djousse, Luc, Cho, Kelly, Wilson, Peter W F, Huffman, Jennifer E, O'Donnell, Christopher J
Published in PloS one (25.05.2022)
Published in PloS one (25.05.2022)
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Journal Article
Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program
Peloso, Gina M, Tcheandjieu, Catherine, McGeary, John E, Posner, Daniel C, Ho, Yuk-Lam, Zhou, Jin J, Hilliard, Austin T, Joseph, Jacob, O'Donnell, Christopher J, Efird, Jimmy T, Crawford, Dana C, Wu, Wen-Chih, Arjomandi, Mehrdad, Sun, Yan V, Assimes, Themistocles L, Huffman, Jennifer E
Published in Frontiers in genetics (03.02.2022)
Published in Frontiers in genetics (03.02.2022)
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Journal Article
Comparison of methods for building polygenic scores for diverse populations
Gunn, Sophia, Wang, Xin, Posner, Daniel C., Cho, Kelly, Huffman, Jennifer E., Gaziano, Michael, Wilson, Peter W., Sun, Yan V., Peloso, Gina, Lunetta, Kathryn L.
Published in HGG advances (25.09.2024)
Published in HGG advances (25.09.2024)
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Journal Article
Protein Identification for Stroke Progression via Mendelian Randomization in Million Veteran Program and UK Biobank
Elmore, Andrew R, Adhikari, Nimish, Hartley, April E, Aparicio, Hugo Javier, Posner, Daniel C, Hemani, Gibran, Tilling, Kate, Gaunt, Tom R, Wilson, Peter W F, Casas, Juan P, Gaziano, John Michael, Davey Smith, George, Paternoster, Lavinia, Cho, Kelly, Peloso, Gina M
Published in Stroke (1970) (01.08.2024)
Published in Stroke (1970) (01.08.2024)
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Journal Article
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Verma, Anurag, Huffman, Jennifer E, Rodriguez, Alex, Conery, Mitchell, Liu, Molei, Ho, Yuk-Lam, Kim, Youngdae, Heise, David A, Guare, Lindsay, Panickan, Vidul Ayakulangara, Garcon, Helene, Linares, Franciel, Costa, Lauren, Goethert, Ian, Tipton, Ryan, Honerlaw, Jacqueline, Davies, Laura, Whitbourne, Stacey, Cohen, Jeremy, Posner, Daniel C, Sangar, Rahul, Murray, Michael, Wang, Xuan, Dochtermann, Daniel R, Devineni, Poornima, Shi, Yunling, Nandi, Tarak Nath, Assimes, Themistocles L, Brunette, Charles A, Carroll, Robert J, Clifford, Royce, Duvall, Scott, Gelernter, Joel, Hung, Adriana, Iyengar, Sudha K, Joseph, Jacob, Kember, Rachel, Kranzler, Henry, Kripke, Colleen M, Levey, Daniel, Luoh, Shiuh-Wen, Merritt, Victoria C, Overstreet, Cassie, Deak, Joseph D, Grant, Struan F A, Polimanti, Renato, Roussos, Panos, Shakt, Gabrielle, Sun, Yan V, Tsao, Noah, Venkatesh, Sanan, Voloudakis, Georgios, Justice, Amy, Begoli, Edmon, Ramoni, Rachel, Tourassi, Georgia, Pyarajan, Saiju, Tsao, Philip, O'Donnell, Christopher J, Muralidhar, Sumitra, Moser, Jennifer, Casas, Juan P, Bick, Alexander G, Zhou, Wei, Cai, Tianxi, Voight, Benjamin F, Cho, Kelly, Gaziano, J Michael, Madduri, Ravi K, Damrauer, Scott, Liao, Katherine P
Published in Science (American Association for the Advancement of Science) (19.07.2024)
Published in Science (American Association for the Advancement of Science) (19.07.2024)
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Journal Article
Convex combination sequence kernel association test for rare‐variant studies
Posner, Daniel C., Lin, Honghuang, Meigs, James B., Kolaczyk, Eric D., Dupuis, Josée
Published in Genetic epidemiology (01.06.2020)
Published in Genetic epidemiology (01.06.2020)
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Journal Article
Pharmacoepidemiology, Machine Learning, and COVID-19: An Intent-to-Treat Analysis of Hydroxychloroquine, With or Without Azithromycin, and COVID-19 Outcomes Among Hospitalized US Veterans
Gerlovin, Hanna, Posner, Daniel C, Ho, Yuk-Lam, Rentsch, Christopher T, Tate, Janet P, King, Joseph T, Kurgansky, Katherine E, Danciu, Ioana, Costa, Lauren, Linares, Franciel A, Goethert, Ian D, Jacobson, Daniel A, Freiberg, Matthew S, Begoli, Edmon, Muralidhar, Sumitra, Ramoni, Rachel B, Tourassi, Georgia, Gaziano, J Michael, Justice, Amy C, Gagnon, David R, Cho, Kelly
Published in American journal of epidemiology (02.11.2021)
Published in American journal of epidemiology (02.11.2021)
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Journal Article
COVID-19 Evidence Accelerator: A parallel analysis to describe the use of Hydroxychloroquine with or without Azithromycin among hospitalized COVID-19 patients
Stewart, Mark, Rodriguez-Watson, Carla, Albayrak, Adem, Asubonteng, Julius, Belli, Andrew, Brown, Thomas, Cho, Kelly, Das, Ritankar, Eldridge, Elizabeth, Gatto, Nicolle, Gelman, Alice, Gerlovin, Hanna, Goldberg, Stuart L, Hansen, Eric, Hirsch, Jonathan, Ho, Yuk-Lam, Ip, Andrew, Izano, Monika, Jones, Jason, Justice, Amy C, Klesh, Reyna, Kuranz, Seth, Lam, Carson, Mao, Qingqing, Mataraso, Samson, Mera, Robertino, Posner, Daniel C, Rassen, Jeremy A, Siefkas, Anna, Schrag, Andrew, Tourassi, Georgia, Weckstein, Andrew, Wolf, Frank, Bhat, Amar, Winckler, Susan, Sigal, Ellen V, Allen, Jeff
Published in PloS one (17.03.2021)
Published in PloS one (17.03.2021)
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Journal Article
Pharmacoepidemiology, Machine Learning and COVID-19: An intent-to-treat analysis of hydroxychloroquine, with or without azithromycin, and COVID-19 outcomes amongst hospitalized US Veterans
Gerlovin, Hanna, Posner, Daniel C, Ho, Yuk-Lam, Rentsch, Christopher T, Tate, Janet P, King Jr, Joseph T, Kurgansky, Katherine E, Danciu, Ioana, Costa, Lauren, Linares, Franciel A, Goethert, Ian D, Jacobson, Daniel A, Freiberg, Matthew S, Begoli, Edmon, Muralidhar, Sumitra, Ramoni, Rachel B, Tourassi, Georgia, Gaziano, J Michael, Justice, Amy C, Gagnon, David R, Cho, Kelly
Published in American Journal of Epidemiology (24.06.2021)
Published in American Journal of Epidemiology (24.06.2021)
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Journal Article
Long-Term Body Mass Index Variability and Adverse Cardiovascular Outcomes
Almuwaqqat, Zakaria, Hui, Qin, Liu, Chang, Zhou, Jin J, Voight, Benjamin F, Ho, Yuk-Lam, Posner, Daniel C, Vassy, Jason L, Gaziano, J Michael, Cho, Kelly, Wilson, Peter W F, Sun, Yan V
Published in JAMA network open (04.03.2024)
Published in JAMA network open (04.03.2024)
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Journal Article
Cardiovascular Disease Risk Assessment Using Traditional Risk Factors and Polygenic Risk Scores in the Million Veteran Program
Vassy, Jason L, Posner, Daniel C, Ho, Yuk-Lam, Gagnon, David R, Galloway, Ashley, Tanukonda, Vidisha, Houghton, Serena C, Madduri, Ravi K, McMahon, Benjamin H, Tsao, Philip S, Damrauer, Scott M, O'Donnell, Christopher J, Assimes, Themistocles L, Casas, Juan P, Gaziano, J Michael, Pencina, Michael J, Sun, Yan V, Cho, Kelly, Wilson, Peter W F
Published in JAMA cardiology (01.06.2023)
Published in JAMA cardiology (01.06.2023)
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Journal Article
Abstract P271: Spatiotemporal Trends of Cardiovascular Incidence in U.S. Veterans From 2003-2018
Polonsky, Tamar S, Posner, Daniel C, Ho, Yuk-Lam, Serra, Monica C, Houghton, Serena C, Ivey, Kerry L, Li, Yanping, Gagnon, David R, Djousse, Luc, Cho, Kelly M, Wilson, Peter W
Published in Circulation (New York, N.Y.) (28.02.2023)
Published in Circulation (New York, N.Y.) (28.02.2023)
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Journal Article
Abstract 10621: Prediction of Incident Atherosclerotic Cardiovascular Disease Using Traditional and Polygenic Risk Score Modeling: The Million Veteran Program Experience
Posner, Daniel C, Vassy, Jason L, Pencina, Michael J, Assimes, Themistocles L, Galloway, Ashley, Ho, Yuk-lam, Gagnon, David R, Casas, Juan P, Damrauer, Scott M, Gaziano, Michael, Cho, Kelly, Wilson, Peter W, Sun, Yan V
Published in Circulation (New York, N.Y.) (16.11.2021)
Published in Circulation (New York, N.Y.) (16.11.2021)
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Journal Article
Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19
Gaziano, Liam, Giambartolomei, Claudia, Pereira, Alexandre C., Gaulton, Anna, Posner, Daniel C., Swanson, Sonja A., Ho, Yuk-Lam, Iyengar, Sudha K., Kosik, Nicole M., Vujkovic, Marijana, Gagnon, David R., Bento, A. Patrícia, Barrio-Hernandez, Inigo, Rönnblom, Lars, Hagberg, Niklas, Lundtoft, Christian, Langenberg, Claudia, Pietzner, Maik, Valentine, Dennis, Gustincich, Stefano, Tartaglia, Gian Gaetano, Allara, Elias, Surendran, Praveen, Burgess, Stephen, Zhao, Jing Hua, Peters, James E., Prins, Bram P., Angelantonio, Emanuele Di, Devineni, Poornima, Shi, Yunling, Lynch, Kristine E., DuVall, Scott L., Garcon, Helene, Thomann, Lauren O., Zhou, Jin J., Gorman, Bryan R., Huffman, Jennifer E., O’Donnell, Christopher J., Tsao, Philip S., Beckham, Jean C., Pyarajan, Saiju, Muralidhar, Sumitra, Huang, Grant D., Ramoni, Rachel, Beltrao, Pedro, Danesh, John, Hung, Adriana M., Chang, Kyong-Mi, Sun, Yan V., Joseph, Jacob, Leach, Andrew R., Edwards, Todd L., Cho, Kelly, Gaziano, J. Michael, Butterworth, Adam S., Casas, Juan P.
Published in Nature medicine (01.04.2021)
Published in Nature medicine (01.04.2021)
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Journal Article
Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program
Rose D L Huang, Xuan-Mai T Nguyen, Gina M Peloso, Mark Trinder, Daniel C Posner, Krishna G Aragam, Yuk-Lam Ho, Julie A Lynch, Scott M Damrauer, Kyong-Mi Chang, Philip S Tsao, Pradeep Natarajan, Themistocles Assimes, J Michael Gaziano, Luc Djousse, Kelly Cho, Peter W F Wilson, Jennifer E Huffman, Christopher J O'Donnell, Veterans Affairs’ Million Veteran Program
Published in PloS one (01.01.2022)
Published in PloS one (01.01.2022)
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Journal Article
Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program
Verma, Anurag, Huffman, Jennifer E, Rodriguez, Alex, Conery, Mitchell, Liu, Molei, Ho, Yuk-Lam, Kim, Youngdae, Heise, David A, Guare, Lindsay, Panickan, Vidul Ayakulangara, Garcon, Helene, Linares, Franciel, Costa, Lauren, Goethert, Ian, Tipton, Ryan, Honerlaw, Jacqueline, Davies, Laura, Whitbourne, Stacey, Cohen, Jeremy, Posner, Daniel C, Sangar, Rahul, Murray, Michael, Wang, Xuan, Dochtermann, Daniel R, Devineni, Poornima, Shi, Yunling, Nandi, Tarak Nath, Assimes, Themistocles L, Brunette, Charles A, Carroll, Robert J, Clifford, Royce, Duvall, Scott, Gelernter, Joel, Hung, Adriana, Iyengar, Sudha K, Joseph, Jacob, Kember, Rachel, Kranzler, Henry, Levey, Daniel, Luoh, Shiuh-Wen, Merritt, Victoria C, Overstreet, Cassie, Deak, Joseph D, Grant, Struan F A, Polimanti, Renato, Roussos, Panos, Sun, Yan V, Venkatesh, Sanan, Voloudakis, Georgios, Justice, Amy, Begoli, Edmon, Ramoni, Rachel, Tourassi, Georgia, Pyarajan, Saiju, Tsao, Philip S, O'Donnell, Christopher J, Muralidhar, Sumitra, Moser, Jennifer, Casas, Juan P, Bick, Alexander G, Zhou, Wei, Cai, Tianxi, Voight, Benjamin F, Cho, Kelly, Gaziano, Michael J, Madduri, Ravi K, Damrauer, Scott M, Liao, Katherine P
Published in medRxiv : the preprint server for health sciences (29.06.2023)
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Published in medRxiv : the preprint server for health sciences (29.06.2023)
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