Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability
Guedan, Sonia, Madar, Aviv, Casado-Medrano, Victoria, Shaw, Carolyn, Wing, Anna, Liu, Fang, Young, Regina M, June, Carl H, Posey, Jr, Avery D
Published in The Journal of clinical investigation (01.06.2020)
Published in The Journal of clinical investigation (01.06.2020)
Get full text
Journal Article
Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
Posey, Avery D., Schwab, Robert D., Boesteanu, Alina C., Steentoft, Catharina, Mandel, Ulla, Engels, Boris, Stone, Jennifer D., Madsen, Thomas D., Schreiber, Karin, Haines, Kathleen M., Cogdill, Alexandria P., Chen, Taylor J., Song, Decheng, Scholler, John, Kranz, David M., Feldman, Michael D., Young, Regina, Keith, Brian, Schreiber, Hans, Clausen, Henrik, Johnson, Laura A., June, Carl H.
Published in Immunity (Cambridge, Mass.) (21.06.2016)
Published in Immunity (Cambridge, Mass.) (21.06.2016)
Get full text
Journal Article
ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells
Guedan, Sonia, Chen, Xi, Madar, Aviv, Carpenito, Carmine, McGettigan, Shannon E., Frigault, Matthew J., Lee, Jihyun, Posey, Avery D., Scholler, John, Scholler, Nathalie, Bonneau, Richard, June, Carl H.
Published in Blood (14.08.2014)
Published in Blood (14.08.2014)
Get full text
Journal Article
Driving cars to the clinic for solid tumors
Castellarin, Mauro, Watanabe, Keisuke, June, Carl H., Kloss, Christopher C., Posey, Avery D.
Published in Gene therapy (01.06.2018)
Published in Gene therapy (01.06.2018)
Get full text
Journal Article
Advances in cancer immunotherapies
Dagher, Oula K., Schwab, Robert D., Brookens, Shawna K., Posey, Avery D.
Published in Cell (13.04.2023)
Published in Cell (13.04.2023)
Get full text
Journal Article
Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
Parker, Kevin R., Migliorini, Denis, Perkey, Eric, Yost, Kathryn E., Bhaduri, Aparna, Bagga, Puneet, Haris, Mohammad, Wilson, Neil E., Liu, Fang, Gabunia, Khatuna, Scholler, John, Montine, Thomas J., Bhoj, Vijay G., Reddy, Ravinder, Mohan, Suyash, Maillard, Ivan, Kriegstein, Arnold R., June, Carl H., Chang, Howard Y., Posey, Avery D., Satpathy, Ansuman T.
Published in Cell (01.10.2020)
Published in Cell (01.10.2020)
Get full text
Journal Article
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells
Kawalekar, Omkar U., O’Connor, Roddy S., Fraietta, Joseph A., Guo, Lili, McGettigan, Shannon E., Posey, Avery D., Patel, Prachi R., Guedan, Sonia, Scholler, John, Keith, Brian, Snyder, Nathaniel W., Blair, Ian A., Milone, Michael C., June, Carl H.
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Get full text
Journal Article
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety
Smole, Anže, Benton, Alexander, Poussin, Mathilde A., Eiva, Monika A., Mezzanotte, Claudia, Camisa, Barbara, Greco, Beatrice, Sharma, Prannda, Minutolo, Nicholas G., Gray, Falon, Bear, Adham S., Baroja, Miren L., Cummins, Casey, Xu, Chong, Sanvito, Francesca, Goldgewicht, Andrea Lang, Blanchard, Tatiana, Rodriguez-Garcia, Alba, Klichinsky, Michael, Bonini, Chiara, June, Carl H., Posey, Avery D., Linette, Gerald P., Carreno, Beatriz M., Casucci, Monica, Powell, Daniel J.
Published in Cancer cell (12.12.2022)
Published in Cancer cell (12.12.2022)
Get full text
Journal Article
Sweet Immune Checkpoint Targets to Enhance T Cell Therapy
Derosiers, Nohelly, Aguilar, William, DeGaramo, David A, Posey, Jr, Avery D
Published in The Journal of immunology (1950) (15.01.2022)
Published in The Journal of immunology (1950) (15.01.2022)
Get full text
Journal Article
Glycan-directed CAR-T cells
Steentoft, Catharina, Migliorini, Denis, King, Tiffany R, Mandel, Ulla, June, Carl H, Posey, Jr, Avery D
Published in Glycobiology (Oxford) (01.09.2018)
Published in Glycobiology (Oxford) (01.09.2018)
Get full text
Journal Article
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting
Bear, Adham S., Blanchard, Tatiana, Cesare, Joseph, Ford, Michael J., Richman, Lee P., Xu, Chong, Baroja, Miren L., McCuaig, Sarah, Costeas, Christina, Gabunia, Khatuna, Scholler, John, Posey, Avery D., O’Hara, Mark H., Smole, Anze, Powell, Daniel J., Garcia, Benjamin A., Vonderheide, Robert H., Linette, Gerald P., Carreno, Beatriz M.
Published in Nature communications (16.07.2021)
Published in Nature communications (16.07.2021)
Get full text
Journal Article
CAR T-Cell Therapies in Glioblastoma: A First Look
Migliorini, Denis, Dietrich, Pierre-Yves, Stupp, Roger, Linette, Gerald P, Posey, Jr, Avery D, June, Carl H
Published in Clinical cancer research (01.02.2018)
Published in Clinical cancer research (01.02.2018)
Get full text
Journal Article
Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager
Wing, Anna, Fajardo, Carlos Alberto, Posey, Jr, Avery D, Shaw, Carolyn, Da, Tong, Young, Regina M, Alemany, Ramon, June, Carl H, Guedan, Sonia
Published in Cancer immunology research (01.05.2018)
Published in Cancer immunology research (01.05.2018)
Get more information
Journal Article
Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma
Johnson, Laura A, Scholler, John, Ohkuri, Takayuki, Kosaka, Akemi, Patel, Prachi R, McGettigan, Shannon E, Nace, Arben K, Dentchev, Tzvete, Thekkat, Pramod, Loew, Andreas, Boesteanu, Alina C, Cogdill, Alexandria P, Chen, Taylor, Fraietta, Joseph A, Kloss, Christopher C, Posey, Jr, Avery D, Engels, Boris, Singh, Reshma, Ezell, Tucker, Idamakanti, Neeraja, Ramones, Melissa H, Li, Na, Zhou, Li, Plesa, Gabriela, Seykora, John T, Okada, Hideho, June, Carl H, Brogdon, Jennifer L, Maus, Marcela V
Published in Science translational medicine (18.02.2015)
Published in Science translational medicine (18.02.2015)
Get more information
Journal Article
Engineering and Design of Chimeric Antigen Receptors
Guedan, Sonia, Calderon, Hugo, Posey, Jr, Avery D, Maus, Marcela V
Published in Molecular therapy. Methods & clinical development (15.03.2019)
Published in Molecular therapy. Methods & clinical development (15.03.2019)
Get full text
Journal Article