Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis
Zhu, Huabin, Klement, John D, Lu, Chunwan, Redd, Priscilla S, Yang, Dafeng, Smith, Alyssa D, Poschel, Dakota B, Zou, Juan, Liu, Ding, Wang, Peng George, Ostrov, David, Coant, Nicolas, Hannun, Yusuf A, Colby, Aaron H, Grinstaff, Mark W, Liu, Kebin
Published in The Journal of immunology (1950) (15.03.2021)
Published in The Journal of immunology (1950) (15.03.2021)
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
Klement, John D., Redd, Priscilla S., Lu, Chunwan, Merting, Alyssa D., Poschel, Dakota B., Yang, Dafeng, Savage, Natasha M., Zhou, Gang, Munn, David H., Fallon, Padraic G., Liu, Kebin
Published in Cancer cell (13.03.2023)
Published in Cancer cell (13.03.2023)
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Journal Article
Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation
Moorman, Hannah R., Poschel, Dakota, Klement, John D., Lu, Chunwan, Redd, Priscilla S., Liu, Kebin
Published in Cancers (15.11.2020)
Published in Cancers (15.11.2020)
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Journal Article
Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth In Vivo
Al Subeh, Zeinab Y., Poschel, Dakota B., Redd, Priscilla S., Klement, John D., Merting, Alyssa D., Yang, Dafeng, Mehta, Megh, Shi, Huidong, Colson, Yolonda L., Oberlies, Nicholas H., Pearce, Cedric J., Colby, Aaron H., Grinstaff, Mark W., Liu, Kebin
Published in ACS nano (23.08.2022)
Published in ACS nano (23.08.2022)
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Journal Article
IRF8: Mechanism of Action and Health Implications
Moorman, Hannah R, Reategui, Yazmin, Poschel, Dakota B, Liu, Kebin
Published in Cells (Basel, Switzerland) (24.08.2022)
Published in Cells (Basel, Switzerland) (24.08.2022)
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Journal Article
PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis
Poschel, Dakota B., Klement, John D., Merting, Alyssa D., Lu, Chunwan, Zhao, Yang, Yang, Dafeng, Xiao, Wei, Zhu, Huabin, Rajeshwari, Ponnala, Toscano, Michael, Jones, Kimya, Barrett, Amanda, Bollag, Roni J., Fallon, Padraic G., Shi, Huidong, Liu, Kebin
Published in Cell reports (Cambridge) (22.10.2024)
Published in Cell reports (Cambridge) (22.10.2024)
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WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape
Lu, Chunwan, Liu, Zhuoqi, Klement, John D, Yang, Dafeng, Merting, Alyssa D, Poschel, Dakota, Albers, Thomas, Waller, Jennifer L, Shi, Huidong, Liu, Kebin
Published in Journal for immunotherapy of cancer (01.07.2021)
Published in Journal for immunotherapy of cancer (01.07.2021)
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Journal Article
IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes
Poschel, Dakota B, Kehinde-Ige, Mercy, Klement, John D, Yang, Dafeng, Merting, Alyssa D, Savage, Natasha M, Shi, Huidong, Liu, Kebin
Published in Cells (Basel, Switzerland) (13.01.2023)
Published in Cells (Basel, Switzerland) (13.01.2023)
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Journal Article
Restoring FAS Expression via Lipid-Encapsulated FAS DNA Nanoparticle Delivery Is Sufficient to Suppress Colon Tumor Growth In Vivo
Merting, Alyssa D, Poschel, Dakota B, Lu, Chunwan, Klement, John D, Yang, Dafeng, Li, Honglin, Shi, Huidong, Chapdelaine, Eric, Montgomery, Mitzi, Redman, Michael T, Savage, Natasha M, Nayak-Kapoor, Asha, Liu, Kebin
Published in Cancers (12.01.2022)
Published in Cancers (12.01.2022)
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Journal Article
Abstract LB036: IRF8 regulates tumor cell sensitivity to intrinsic ferroptosis by repressing p53
Poschel, Dakota, Kehinde-Ige, Mercy, Klement, John, Yang, Dafeng, Merting, Alyssa, Savage, Natasha, Shi, Huidong, Liu, Kebin
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Journal Article
PD-L1 restrains PD-1 + Nrp1 lo Treg cells to suppress inflammation-driven colorectal tumorigenesis
Poschel, Dakota B, Klement, John D, Merting, Alyssa D, Lu, Chunwan, Zhao, Yang, Yang, Dafeng, Xiao, Wei, Zhu, Huabin, Rajeshwari, Ponnala, Toscano, Michael, Jones, Kimya, Barrett, Amanda, Bollag, Roni J, Fallon, Padraic G, Shi, Huidong, Liu, Kebin
Published in Cell reports (Cambridge) (03.10.2024)
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Published in Cell reports (Cambridge) (03.10.2024)
Journal Article
Tumor PD-L1 selectively suppresses type I interferon in myeloid cells to suppress CTL recruitment to promote lung metastasis
Klement, John D, Redd, Priscilla S, Lu, Chunwan, Merting, Alyssa D, Poschel, Dakota B, Yang, Dafeng, Zhou, Gang, Munn, David H, Liu, Kebin
Published in bioRxiv (18.06.2021)
Published in bioRxiv (18.06.2021)
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