Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
Kurppa, Kari J., Liu, Yao, To, Ciric, Zhang, Tinghu, Fan, Mengyang, Vajdi, Amir, Knelson, Erik H., Xie, Yingtian, Lim, Klothilda, Cejas, Paloma, Portell, Andrew, Lizotte, Patrick H., Ficarro, Scott B., Li, Shuai, Chen, Ting, Haikala, Heidi M., Wang, Haiyun, Bahcall, Magda, Gao, Yang, Shalhout, Sophia, Boettcher, Steffen, Shin, Bo Hee, Thai, Tran, Wilkens, Margaret K., Tillgren, Michelle L., Mushajiang, Mierzhati, Xu, Man, Choi, Jihyun, Bertram, Arrien A., Ebert, Benjamin L., Beroukhim, Rameen, Bandopadhayay, Pratiti, Awad, Mark M., Gokhale, Prafulla C., Kirschmeier, Paul T., Marto, Jarrod A., Camargo, Fernando D., Haq, Rizwan, Paweletz, Cloud P., Wong, Kwok-Kin, Barbie, David A., Long, Henry W., Gray, Nathanael S., Jänne, Pasi A.
Published in Cancer cell (13.01.2020)
Published in Cancer cell (13.01.2020)
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3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade
Aref, Amir R, Campisi, Marco, Ivanova, Elena, Portell, Andrew, Larios, Dalia, Piel, Brandon P, Mathur, Natasha, Zhou, Chensheng, Coakley, Raven Vlahos, Bartels, Alan, Bowden, Michaela, Herbert, Zach, Hill, Sarah, Gilhooley, Sean, Carter, Jacob, Cañadas, Israel, Thai, Tran C, Kitajima, Shunsuke, Chiono, Valeria, Paweletz, Cloud P, Barbie, David A, Kamm, Roger D, Jenkins, Russell W
Published in Lab on a chip (09.10.2018)
Published in Lab on a chip (09.10.2018)
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Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity
Mahadevan, Navin R, Knelson, Erik H, Wolff, Jacquelyn O, Vajdi, Amir, Saigí, Maria, Campisi, Marco, Hong, Deli, Thai, Tran C, Piel, Brandon, Han, Saemi, Reinhold, Bruce B, Duke-Cohan, Jonathan S, Poitras, Michael J, Taus, Luke J, Lizotte, Patrick H, Portell, Andrew, Quadros, Victor, Santucci, Alison D, Murayama, Takahiko, Cañadas, Israel, Kitajima, Shunsuke, Akitsu, Aoi, Fridrikh, Maya, Watanabe, Hideo, Reardon, Brendan, Gokhale, Prafulla C, Paweletz, Cloud P, Awad, Mark M, Van Allen, Eliezer M, Lako, Ana, Wang, Xi-Tao, Chen, Benjamin, Hong, Fangxin, Sholl, Lynette M, Tolstorukov, Michael Y, Pfaff, Kathleen, Jänne, Pasi A, Gjini, Evisa, Edwards, Robin, Rodig, Scott, Reinherz, Ellis L, Oser, Matthew G, Barbie, David A
Published in Cancer discovery (01.08.2021)
Published in Cancer discovery (01.08.2021)
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Use of Ex Vivo Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for HER2 Mutant Non-Small Cell Lung Cancer
Ivanova, Elena, Kuraguchi, Mari, Xu, Man, Portell, Andrew J, Taus, Luke, Diala, Irmina, Lalani, Alshad S, Choi, Jihyun, Chambers, Emily S, Li, Shuai, Liu, Shengwu, Chen, Ting, Barbie, Thanh U, Oxnard, Geoffrey R, Haworth, Jacob J, Wong, Kwok-Kin, Dahlberg, Suzanne E, Aref, Amir A, Barbie, David A, Bahcall, Magda, Paweletz, Cloud P, Jänne, Pasi A
Published in Clinical cancer research (15.05.2020)
Published in Clinical cancer research (15.05.2020)
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Interface-guided phenotyping of coding variants in the transcription factor RUNX1
Ozturk, Kivilcim, Panwala, Rebecca, Sheen, Jeanna, Ford, Kyle, Jayne, Nathan, Portell, Andrew, Zhang, Dong-Er, Hutter, Stephan, Haferlach, Torsten, Ideker, Trey, Mali, Prashant, Carter, Hannah
Published in Cell reports (Cambridge) (23.07.2024)
Published in Cell reports (Cambridge) (23.07.2024)
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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
Sade-Feldman, Moshe, Yizhak, Keren, Bjorgaard, Stacey L., Ray, John P., de Boer, Carl G., Jenkins, Russell W., Lieb, David J., Chen, Jonathan H., Frederick, Dennie T., Barzily-Rokni, Michal, Freeman, Samuel S., Reuben, Alexandre, Hoover, Paul J., Villani, Alexandra-Chloé, Ivanova, Elena, Portell, Andrew, Lizotte, Patrick H., Aref, Amir R., Eliane, Jean-Pierre, Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Li, Bo, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Cooper, Zachary A., Paweletz, Cloud P., Barbie, David A., Stemmer-Rachamimov, Anat, Flaherty, Keith T., Wargo, Jennifer A., Boland, Genevieve M., Sullivan, Ryan J., Getz, Gad, Hacohen, Nir
Published in Cell (01.11.2018)
Published in Cell (01.11.2018)
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Journal Article
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
Sade-Feldman, Moshe, Yizhak, Keren, Bjorgaard, Stacey L., Ray, John P., de Boer, Carl G., Jenkins, Russell W., Lieb, David J., Chen, Jonathan H., Frederick, Dennie T., Barzily-Rokni, Michal, Freeman, Samuel S., Reuben, Alexandre, Hoover, Paul J., Villani, Alexandra-Chloé, Ivanova, Elena, Portell, Andrew, Lizotte, Patrick H., Aref, Amir R., Eliane, Jean-Pierre, Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Li, Bo, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Cooper, Zachary A., Paweletz, Cloud P., Barbie, David A., Stemmer-Rachamimov, Anat, Flaherty, Keith T., Wargo, Jennifer A., Boland, Genevieve M., Sullivan, Ryan J., Getz, Gad, Hacohen, Nir
Published in Cell (10.01.2019)
Published in Cell (10.01.2019)
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Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade
Sehgal, Kartik, Portell, Andrew, Ivanova, Elena V, Lizotte, Patrick H, Mahadevan, Navin R, Greene, Jonathan R, Vajdi, Amir, Gurjao, Carino, Teceno, Tyler, Taus, Luke J, Thai, Tran C, Kitajima, Shunsuke, Liu, Derek, Tani, Tetsuo, Noureddine, Moataz, Lau, Christie J, Kirschmeier, Paul T, Liu, David, Giannakis, Marios, Jenkins, Russell W, Gokhale, Prafulla C, Goldoni, Silvia, Pinzon-Ortiz, Maria, Hastings, William D, Hammerman, Peter S, Miret, Juan J, Paweletz, Cloud P, Barbie, David A
Published in The Journal of clinical investigation (19.01.2021)
Published in The Journal of clinical investigation (19.01.2021)
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Abstract 5025: From OR to bench: Identification of variables affecting success in generating patient derived organotypic spheroids (pDOTS)
Larios, Dalia, Aref, Amir, Ivanova, Elena, Piel, Brandon, Portell, Andrew, Barbie, David A., Bueno, Raphael, Paweletz, Cloud
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 1483: Ex vivo single cell RNA-sequencing of tumor derived organotypic spheroids identifies a unique mesenchymal resistance program to PD-1 blockade
Portell, Andrew J., Greene, Jonathan, Taus, Luke J., Lizotte, Patrick, Ivanova, Elena, Menezes, Kalil O., Aref, Amir R., Kirschmeier, Paul, Jenkins, Russell W., Barbie, David, Paweletz, Cloud P.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Adipose Stem Cells Enhance Nerve Regeneration and Muscle Function in a Peroneal Nerve Ablation Model
Passipieri, Juliana A, Dienes, Jack, Frank, Joseph, Glazier, Joshua, Portell, Andrew, Venkatesh, Kaushik P, Bliley, Jacqueline M, Grybowski, Damian, Schilling, Benjamin K, Marra, Kacey G, Christ, George J
Published in Tissue engineering. Part A (01.03.2021)
Published in Tissue engineering. Part A (01.03.2021)
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Abstract 988: Short-term culture of organotypic tumor spheroids derived from patient xenografts in a novel 3D microfluidic chip predicts in vivo response of targeted therapies
Aref, Amir, Ivanova, Elena, Chambers, Emily, Portell, Andrew, Jenkins, Russell, Lin, Mika, Xu, Man, Haworth, Jacob, Bahcall, Magda, Paweletz, Cloud, Janne, Pasi
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Robust genome and cell engineering via in vitro and in situ circularized RNAs
Tong, Michael, Palmer, Nathan, Dailamy, Amir, Kumar, Aditya, Khaliq, Hammza, Han, Sangwoo, Finburgh, Emma, Wing, Madeleine, Hong, Camilla, Xiang, Yichen, Miyasaki, Katelyn, Portell, Andrew, Rainaldi, Joseph, Suhardjo, Amanda, Nourreddine, Sami, Chew, Wei Leong, Kwon, Ester J, Mali, Prashant
Published in Nature biomedical engineering (26.08.2024)
Published in Nature biomedical engineering (26.08.2024)
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248 Immunotherapy persister cells uncovered by dynamic single-cell RNA-sequencing
Sehgal, Kartik, Portell, Andrew, Ivanova, Elena, Lizotte, Patrick, Mahadevan, Navin, Greene, Jonathan, Vadji, Amir, Carino Gurjao, Tyler Teceno, Taus, Luke, Tran, Thai, Kitajima, Shunsuke, Liu, Derek, Tani, Tetsuo, Noureddine, Moataz, Lau, Christie, Kirschmeier, Paul, Liu, David, Giannakis, Marios, Jenkins, Russell, Gokhale, Prafulla, Goldoni, Silvia, Pinzon-Ortiz, Maria, Hastings, William, Hammerman, Peter, Miret, Juan, Cloud Paweletz, Barbie, David
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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