Molecular engineering of safe and efficacious oral basal insulin
Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas
Published in Nature communications (27.07.2020)
Published in Nature communications (27.07.2020)
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Author Correction: Molecular engineering of safe and efficacious oral basal insulin
Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas
Published in Nature communications (20.08.2020)
Published in Nature communications (20.08.2020)
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5842 ULTRASOUND AND 3D IMAGING CHARACTERISATION OF A RAT MODEL OF POLYCYSTIC KIDNEY DISEASE
Christensen, Michael, Porsgaard, Trine, Perens, Johanne, Sembach, Frederikke Emilie, Hansen, Henrik Björk, Ougaard, Maria
Published in Nephrology, dialysis, transplantation (14.06.2023)
Published in Nephrology, dialysis, transplantation (14.06.2023)
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Ultrasound and 3D Imaging Characterisation of a Rat Model of Polycystic Kidney Disease: SA-PO786
Ougaard, Maria K., Porsgaard, Trine, Sembach, Frederikke E., Thisted, Louise, Skytte, Jacob L., Perens, Johanna, Christensen, Michael
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans
Kjeldsen, Thomas B, Hubálek, František, Hjørringgaard, Claudia U, Tagmose, Tina M, Nishimura, Erica, Stidsen, Carsten E, Porsgaard, Trine, Fledelius, Christian, Refsgaard, Hanne H. F, Gram-Nielsen, Sanne, Naver, Helle, Pridal, Lone, Hoeg-Jensen, Thomas, Jeppesen, Claus Bekker, Manfè, Valentina, Ludvigsen, Svend, Lautrup-Larsen, Inger, Madsen, Peter
Published in Journal of medicinal chemistry (08.07.2021)
Published in Journal of medicinal chemistry (08.07.2021)
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1665-P: Whole-Brain Activation Signatures of Weight-Lowering Drugs
DALBOEGE, LOUISE S., TOZZI, MARCO, SALINAS, CASPER G., PORSGAARD, TRINE, THORBEK, DITTE D., SKYTTE, JACOB L., ROOSTALU, URMAS, HANSEN, HENRIK H., PERENS, JOHANNA, HECKSHER-SØRENSEN, JACOB
Published in Diabetes (New York, N.Y.) (20.06.2023)
Published in Diabetes (New York, N.Y.) (20.06.2023)
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Machine-Learning-Guided Peptide Drug Discovery: Development of GLP‑1 Receptor Agonists with Improved Drug Properties
Nielsen, Jens Christian, Hjo̷rringgaard, Claudia, Nygaard, Mads Mo̷rup, Wester, Anita, Elster, Lisbeth, Porsgaard, Trine, Mikkelsen, Randi Bonke, Rasmussen, Silas, Madsen, Andreas Nygaard, Schlein, Morten, Vrang, Niels, Rigbolt, Kristoffer, Dalbo̷ge, Louise S.
Published in Journal of medicinal chemistry (25.07.2024)
Published in Journal of medicinal chemistry (25.07.2024)
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Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320
Kjeldsen, Thomas B., Hubalek, Frantisek, Tagmose, Tina M., Pridal, Lone, Refsgaard, Hanne H. F., Porsgaard, Trine, Gram-Nielsen, Sanne, Hovgaard, Lars, Valore, Henrik, Munzel, Martin, Hjorringgaard, Claudia U., Jeppesen, Claus Bekker, Manfe, Valentina, Hoeg-Jensen, Thomas, Ludvigsen, Svend, Nielsen, Peter Kresten, Lautrup-Larsen, Inger, Stidsen, Carsten E., Wulff, Erik M., Garibay, Patrick W., Kodra, Janos T., Nishimura, Erica, Madsen, Peter
Published in Journal of medicinal chemistry (14.01.2021)
Published in Journal of medicinal chemistry (14.01.2021)
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Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research
Jensen, Victoria S, Porsgaard, Trine, Lykkesfeldt, Jens, Hvid, Henning
Published in American journal of translational research (01.01.2016)
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Published in American journal of translational research (01.01.2016)
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Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs
Gradel, Anna Katrina Jógvansdóttir, Kildegaard, Jonas, Porsgaard, Trine, Lykkesfeldt, Jens, Refsgaard, Hanne Hoffman Frølund
Published in Basic & clinical pharmacology & toxicology (01.06.2021)
Published in Basic & clinical pharmacology & toxicology (01.06.2021)
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Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, Trine, Lykkesfeldt, Jens, Brockhoff, Per Bruun, Seested, Torben, Refsgaard, Hanne Hoffmann Frølund
Published in Experimental and clinical endocrinology & diabetes (01.05.2020)
Published in Experimental and clinical endocrinology & diabetes (01.05.2020)
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The counterregulatory response to hypoglycaemia in the pig
Gradel, Anna Katrina J., Kildegaard, Jonas, Ludvigsen, Trine P., Porsgaard, Trine, Schou‐Pedersen, Anne Marie V., Fels, Johannes J., Lykkesfeldt, Jens, Refsgaard, Hanne H. F.
Published in Basic & clinical pharmacology & toxicology (01.10.2020)
Published in Basic & clinical pharmacology & toxicology (01.10.2020)
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Intraintestinal and Parenteral Administration of an Insulin Analogue Leads to Comparable Activation of Signaling Downstream of the Insulin Receptor in the Small Intestine
Hvid, Henning, Kildegaard, Jonas, Kristensen, Kim, Porsgaard, Trine, Jørgensen, Mikkel S., Ballarín-González, Borja, Ahnfelt-Rønne, Jonas, Hansen, Bo F., Nishimura, Erica
Published in Journal of diabetes science and technology (01.01.2020)
Published in Journal of diabetes science and technology (01.01.2020)
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Construction of Insulin 18-mer Nanoassemblies Driven by Coordination to Iron(II) and Zinc(II) Ions at Distinct Sites
Munch, Henrik K., Nygaard, Jesper, Christensen, Niels Johan, Engelbrekt, Christian, Østergaard, Mads, Porsgaard, Trine, Hoeg-Jensen, Thomas, Zhang, Jingdong, Arleth, Lise, Thulstrup, Peter W., Jensen, Knud J.
Published in Angewandte Chemie International Edition (12.02.2016)
Published in Angewandte Chemie International Edition (12.02.2016)
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Oral insulin (human, murine, or porcine) does not prevent diabetes in the non-obese diabetic mouse
Pham, Minh N, Gibson, Claire, Rydén, Anna K.E, Perdue, Nikole, Boursalian, Tamar E, Pagni, Philippe P, Coppieters, Ken, Skonberg, Christian, Porsgaard, Trine, von Herrath, Matthias, Vela, Jose Luis
Published in Clinical immunology (Orlando, Fla.) (01.03.2016)
Published in Clinical immunology (Orlando, Fla.) (01.03.2016)
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