BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors
Reisländer, Timo, Lombardi, Emilia Puig, Groelly, Florian J., Miar, Ana, Porru, Manuela, Di Vito, Serena, Wright, Benjamin, Lockstone, Helen, Biroccio, Annamaria, Harris, Adrian, Londoño-Vallejo, Arturo, Tarsounas, Madalena
Published in Nature communications (17.07.2019)
Published in Nature communications (17.07.2019)
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MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer
Dinami, Roberto, Pompili, Luca, Petti, Eleonora, Porru, Manuela, D'Angelo, Carmen, Di Vito, Serena, Rizzo, Angela, Campani, Virginia, De Rosa, Giuseppe, Bruna, Alejandra, Serra, Violeta, Mano, Miguel, Giacca, Mauro, Leonetti, Carlo, Ciliberto, Gennaro, Tarsounas, Madalena, Stoppacciaro, Antonella, Schoeftner, Stefan, Biroccio, Annamaria
Published in EMBO molecular medicine (11.01.2023)
Published in EMBO molecular medicine (11.01.2023)
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Adipose-derived stem cell-mediated paclitaxel delivery inhibits breast cancer growth
Scioli, Maria Giovanna, Artuso, Simona, D'Angelo, Carmen, Porru, Manuela, D'Amico, Federico, Bielli, Alessandra, Gentile, Pietro, Cervelli, Valerio, Leonetti, Carlo, Orlandi, Augusto
Published in PloS one (07.09.2018)
Published in PloS one (07.09.2018)
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Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs
Puca, Rosa, Nardinocchi, Lavinia, Porru, Manuela, Simon, Amos J., Rechavi, Gideon, Leonetti, Carlo, Givol, David, D'Orazi, Gabriella
Published in Cell cycle (Georgetown, Tex.) (15.05.2011)
Published in Cell cycle (Georgetown, Tex.) (15.05.2011)
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Anti‐tumoural activity of the G‐quadruplex ligand pyridostatin against BRCA1/2‐deficient tumours
Groelly, Florian J, Porru, Manuela, Zimmer, Jutta, Benainous, Hugo, De Visser, Yanti, Kosova, Anastasiya A, Di Vito, Serena, Serra, Violeta, Ryan, Anderson, Leonetti, Carlo, Bruna, Alejandra, Biroccio, Annamaria, Tarsounas, Madalena
Published in EMBO molecular medicine (07.03.2022)
Published in EMBO molecular medicine (07.03.2022)
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Hybrid Self-Assembling Nanoparticles Encapsulating Zoledronic Acid: A Strategy for Fostering Their Clinical Use
Abate, Marianna, Scotti, Lorena, Nele, Valeria, Caraglia, Michele, Biondi, Marco, De Rosa, Giuseppe, Leonetti, Carlo, Campani, Virginia, Zappavigna, Silvia, Porru, Manuela
Published in International journal of molecular sciences (05.05.2022)
Published in International journal of molecular sciences (05.05.2022)
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DARPP-32 and t-DARPP in the development of resistance to anti-HER2 agents. Pre-clinical evidence from the STEP study
Bon, Giulia, Krasniqi, Eriseld, Porru, Manuela, D'Ambrosio, Lorenzo, Scalera, Stefano, Maugeri-Saccà, Marcello, Di Lisa, Francesca Sofia, Filomeno, Lorena, Arcuri, Teresa, Botticelli, Andrea, Santini, Daniele, Fabbri, Maria Agnese, D'Auria, Giuliana, Pulito, Claudio, Blandino, Giovanni, Marchiò, Caterina, Barba, Maddalena, Ciliberto, Gennaro, Vici, Patrizia, Pizzuti, Laura
Published in Neoplasia (New York, N.Y.) (01.11.2023)
Published in Neoplasia (New York, N.Y.) (01.11.2023)
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Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway
Rizzo, Angela, Salvati, Erica, Porru, Manuela, D’Angelo, Carmen, Stevens, Malcolm F., D’Incalci, Maurizio, Leonetti, Carlo, Gilson, Eric, Zupi, Gabriella, Biroccio, Annamaria
Published in Nucleic acids research (01.09.2009)
Published in Nucleic acids research (01.09.2009)
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A New Avenue toward Androgen Receptor Pan-antagonists: C2 Sterically Hindered Substitution of Hydroxy-propanamides
Guerrini, Andrea, Tesei, Anna, Ferroni, Claudia, Paganelli, Giulia, Zamagni, Alice, Carloni, Silvia, Di Donato, Marzia, Castoria, Gabriella, Leonetti, Carlo, Porru, Manuela, De Cesare, Michelandrea, Zaffaroni, Nadia, Beretta, Giovanni Luca, Del Rio, Alberto, Varchi, Greta
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects
Romito, Ilaria, Porru, Manuela, Braghini, Maria Rita, Pompili, Luca, Panera, Nadia, Crudele, Annalisa, Gnani, Daniela, De Stefanis, Cristiano, Scarsella, Marco, Pomella, Silvia, Levi Mortera, Stefano, de Billy, Emmanuel, Conti, Adrian Libenzio, Marzano, Valeria, Putignani, Lorenza, Vinciguerra, Manlio, Balsano, Clara, Pastore, Anna, Rota, Rossella, Tartaglia, Marco, Leonetti, Carlo, Alisi, Anna
Published in Journal of experimental & clinical cancer research (16.11.2021)
Published in Journal of experimental & clinical cancer research (16.11.2021)
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BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity
Tacconi, Eliana MC, Lai, Xianning, Folio, Cecilia, Porru, Manuela, Zonderland, Gijs, Badie, Sophie, Michl, Johanna, Sechi, Irene, Rogier, Mélanie, Matía García, Verónica, Batra, Ankita Sati, Rueda, Oscar M, Bouwman, Peter, Jonkers, Jos, Ryan, Anderson, Reina‐San‐Martin, Bernardo, Hui, Joannie, Tang, Nelson, Bruna, Alejandra, Biroccio, Annamaria, Tarsounas, Madalena
Published in EMBO molecular medicine (01.10.2017)
Published in EMBO molecular medicine (01.10.2017)
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TRF2 as novel marker of tumor response to taxane-based therapy: from mechanistic insight to clinical implication
Iachettini, Sara, Terrenato, Irene, Porru, Manuela, Di Vito, Serena, Rizzo, Angela, D'Angelo, Carmen, Petti, Eleonora, Dinami, Roberto, Maresca, Carmen, Di Benedetto, Anna, Palange, Aldo, Mulè, Antonino, Santoro, Angela, Palazzo, Antonella, Fuso, Paola, Stoppacciaro, Antonella, Vici, Patrizia, Filomeno, Lorena, Di Lisa, Francesca Sofia, Arcuri, Teresa, Krasniqi, Eriseld, Fabi, Alessandra, Biroccio, Annamaria, Zizza, Pasquale
Published in Journal of experimental & clinical cancer research (09.03.2024)
Published in Journal of experimental & clinical cancer research (09.03.2024)
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Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo
Nardinocchi, Lavinia, Pantisano, Valentina, Puca, Rosa, Porru, Manuela, Aiello, Aurora, Grasselli, Annalisa, Leonetti, Carlo, Safran, Michal, Rechavi, Gideon, Givol, David, Farsetti, Antonella, D'Orazi, Gabriella
Published in PloS one (13.12.2010)
Published in PloS one (13.12.2010)
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Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid
Misso, Gabriella, Porru, Manuela, Stoppacciaro, Antonella, Castellano, Maria, De Cicco, Federica, Leonetti, Carlo, Santini, Daniele, Caraglia, Michele
Published in Cancer biology & therapy (01.12.2012)
Published in Cancer biology & therapy (01.12.2012)
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Chlorambucil targets BRCA1/2‐deficient tumours and counteracts PARP inhibitor resistance
Tacconi, Eliana MC, Badie, Sophie, De Gregoriis, Giuliana, Reisländer, Timo, Lai, Xianning, Porru, Manuela, Folio, Cecilia, Moore, John, Kopp, Arnaud, Baguña Torres, Júlia, Sneddon, Deborah, Green, Marcus, Dedic, Simon, Lee, Jonathan W, Batra, Ankita Sati, Rueda, Oscar M, Bruna, Alejandra, Leonetti, Carlo, Caldas, Carlos, Cornelissen, Bart, Brino, Laurent, Ryan, Anderson, Biroccio, Annamaria, Tarsounas, Madalena
Published in EMBO molecular medicine (01.07.2019)
Published in EMBO molecular medicine (01.07.2019)
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TRF2 and VEGF-A: an unknown relationship with prognostic impact on survival of colorectal cancer patients
Dinami, Roberto, Porru, Manuela, Amoreo, Carla Azzurra, Sperduti, Isabella, Mottolese, Marcella, Buglioni, Simonetta, Marinelli, Daniele, Maugeri-Saccà, Marcello, Sacconi, Andrea, Blandino, Giovanni, Leonetti, Carlo, Di Rocco, Giuliana, Verdina, Alessandra, Spinella, Francesca, Fiorentino, Francesco, Ciliberto, Gennaro, Biroccio, Annamaria, Zizza, Pasquale
Published in Journal of experimental & clinical cancer research (15.06.2020)
Published in Journal of experimental & clinical cancer research (15.06.2020)
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Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
Pecci, Valeria, Troisi, Fabiola, Aiello, Aurora, De Martino, Sara, Carlino, Angela, Fiorentino, Vincenzo, Ripoli, Cristian, Rotili, Dante, Pierconti, Francesco, Martini, Maurizio, Porru, Manuela, Pinto, Francesco, Mai, Antonello, Bassi, Pier Francesco, Grassi, Claudio, Gaetano, Carlo, Pontecorvi, Alfredo, Strigari, Lidia, Farsetti, Antonella, Nanni, Simona
Published in Cancer cell international (05.02.2024)
Published in Cancer cell international (05.02.2024)
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Fluorescent nanodiamonds as innovative delivery systems for MiR-34a replacement in breast cancer
Abate, Marianna, Lombardi, Angela, Luce, Amalia, Porru, Manuela, Leonetti, Carlo, Bocchetti, Marco, Campani, Virginia, De Rosa, Giuseppe, Graziano, Sossio Fabio, Nele, Valeria, Cardile, Francesco, Marino, Federica Zito, Franco, Renato, Ronchi, Andrea, Scrima, Marianna, Sperlongano, Rossella, Alfano, Roberto, Misso, Gabriella, Amler, Evzen, Caraglia, Michele, Zappavigna, Silvia
Published in Molecular therapy. Nucleic acids (12.09.2023)
Published in Molecular therapy. Nucleic acids (12.09.2023)
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Correction to: Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects
Romito, Ilaria, Porru, Manuela, Braghini, Maria Rita, Pompili, Luca, Panera, Nadia, Crudele, Annalisa, Gnani, Daniela, De Stefanis, Cristiano, Scarsella, Marco, Pomella, Silvia, Mortera, Stefano Levi, de Billy, Emmanuel, Conti, Adrian Libenzio, Marzano, Valeria, Putignani, Lorenza, Vinciguerra, Manlio, Balsano, Clara, Pastore, Anna, Rota, Rossella, Tartaglia, Marco, Leonetti, Carlo, Alisi, Anna
Published in Journal of experimental & clinical cancer research (27.01.2022)
Published in Journal of experimental & clinical cancer research (27.01.2022)
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