An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action
Gibbs, Julie, Ince, Louise, Matthews, Laura, Mei, Junjie, Bell, Thomas, Yang, Nan, Saer, Ben, Begley, Nicola, Poolman, Toryn, Pariollaud, Marie, Farrow, Stuart, DeMayo, Francesco, Hussell, Tracy, Worthen, G Scott, Ray, David, Loudon, Andrew
Published in Nature medicine (01.08.2014)
Published in Nature medicine (01.08.2014)
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Journal Article
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia
Kitchen, Gareth B., Cunningham, Peter S., Poolman, Toryn M., Iqbal, Mudassar, Maidstone, Robert, Baxter, Matthew, Bagnall, James, Begley, Nicola, Saer, Ben, Hussell, Tracy, Matthews, Laura C., Dockrell, David H., Durrington, Hannah J., Gibbs, Julie E., Blaikley, John F., Loudon, Andrew S., Ray, David W.
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2020)
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Journal Article
REVERBa couples the circadian clock to hepatic glucocorticoid action
Caratti, Giorgio, Iqbal, Mudassar, Hunter, Louise, Kim, Donghwan, Wang, Ping, Vonslow, Ryan M, Begley, Nicola, Tetley, Abigail J, Woodburn, Joanna L, Pariollaud, Marie, Maidstone, Robert, Donaldson, Ian J, Zhang, Zhenguang, Ince, Louise M, Kitchen, Gareth, Baxter, Matthew, Poolman, Toryn M, Daniels, Dion A, Stirling, David R, Brocker, Chad, Gonzalez, Frank, Loudon, Andrew Si, Bechtold, David A, Rattray, Magnus, Matthews, Laura C, Ray, David W
Published in The Journal of clinical investigation (01.10.2018)
Published in The Journal of clinical investigation (01.10.2018)
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Journal Article
The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and transcriptomic features of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
Harris, Shelley E, Poolman, Toryn M, Arvaniti, Anastasia, Cox, Roger D, Gathercole, Laura L, Tomlinson, Jeremy W
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2020)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2020)
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Journal Article
Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism
Hunter, A. Louise, Pelekanou, Charlotte E., Adamson, Antony, Downton, Polly, Barron, Nichola J., Cornfield, Thomas, Poolman, Toryn M., Humphreys, Neil, Cunningham, Peter S., Hodson, Leanne, Loudon, Andrew S. I., Iqbal, Mudassar, Bechtold, David A., Ray, David W.
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2020)
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Journal Article
Rheumatoid arthritis reprograms circadian output pathways
Poolman, Toryn M, Gibbs, Julie, Walker, Amy L, Dickson, Suzanna, Farrell, Laura, Hensman, James, Kendall, Alexandra C, Maidstone, Robert, Warwood, Stacey, Loudon, Andrew, Rattray, Magnus, Bruce, Ian N, Nicolaou, Anna, Ray, David W
Published in Arthritis research & therapy (06.02.2019)
Published in Arthritis research & therapy (06.02.2019)
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Journal Article
HNF4A modulates glucocorticoid action in the liver
Hunter, A. Louise, Poolman, Toryn M., Kim, Donghwan, Gonzalez, Frank J., Bechtold, David A., Loudon, Andrew S.I., Iqbal, Mudassar, Ray, David W.
Published in Cell reports (Cambridge) (19.04.2022)
Published in Cell reports (Cambridge) (19.04.2022)
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Journal Article
Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism
Downton, Polly, Sanna, Fabio, Maidstone, Robert, Poolman, Toryn M, Hayter, Edward A, Dickson, Suzanna H, Ciccone, Nick A, Early, James O, Adamson, Antony, Spiller, David G, Simpkins, Devin A, Baxter, Matthew, Fischer, Roman, Rattray, Magnus, Loudon, Andrew S I, Gibbs, Julie E, Bechtold, David A, Ray, David W
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2022)
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Journal Article
An improved method for quantitative ChIP studies of nuclear receptor function
Hunter, Ann Louise, Narang, Natasha, Baxter, Matthew, Ray, David W, Poolman, Toryn M
Published in Journal of molecular endocrinology (01.05.2019)
Published in Journal of molecular endocrinology (01.05.2019)
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Journal Article
Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy
Matthews, Laura C., Berry, Andrew A., Morgan, David J., Poolman, Toryn M., Bauer, Kerstin, Kramer, Frederike, Spiller, David G., Richardson, Rachel V., Chapman, Karen E., Farrow, Stuart N., Norman, Michael R., Williamson, Andrew J. K., Whetton, Anthony D., Taylor, Stephen S., Tuckermann, Jan P., White, Michael R. H., Ray, David W.
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2015)
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Journal Article
Angiotensin II–Mediated Oxidative DNA Damage Accelerates Cellular Senescence in Cultured Human Vascular Smooth Muscle Cells via Telomere-Dependent and Independent Pathways
Herbert, Karl E, Mistry, Yogita, Hastings, Richard, Poolman, Toryn, Niklason, Laura, Williams, Bryan
Published in Circulation research (01.02.2008)
Published in Circulation research (01.02.2008)
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Journal Article
Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production
Morgan, David J., Poolman, Toryn M., Williamson, Andrew J. K., Wang, Zichen, Clark, Neil R., Ma’ayan, Avi, Whetton, Anthony D., Brass, Andrew, Matthews, Laura C., Ray, David W.
Published in Scientific reports (26.05.2016)
Published in Scientific reports (26.05.2016)
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Journal Article
The Methyltransferase WBSCR22/Merm1 Enhances Glucocorticoid Receptor Function and Is Regulated in Lung Inflammation and Cancer
Jangani, Maryam, Poolman, Toryn M., Matthews, Laura, Yang, Nan, Farrow, Stuart N., Berry, Andrew, Hanley, Neil, Williamson, Andrew J.K., Whetton, Anthony D., Donn, Rachelle, Ray, David W.
Published in The Journal of biological chemistry (28.03.2014)
Published in The Journal of biological chemistry (28.03.2014)
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Journal Article
Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1
McCaffrey, James C., Webb, Nicholas J., Poolman, Toryn M., Fresquet, Maryline, Moxey, Cressida, Zeef, Leo A. H., Donaldson, Ian J., Ray, David W., Lennon, Rachel
Published in Scientific reports (27.07.2017)
Published in Scientific reports (27.07.2017)
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Journal Article
AKR1D1 knockout mice develop a sex-dependent metabolic phenotype
Gathercole, Laura L, Nikolaou, Nikolaos, Harris, Shelley E, Arvaniti, Anastasia, Poolman, Toryn M, Hazlehurst, Jonathan M, Kratschmar, Denise V, Todorčević, Marijana, Moolla, Ahmad, Dempster, Niall, Pink, Ryan C, Saikali, Michael F, Bentley, Liz, Penning, Trevor M, Ohlsson, Claes, Cummins, Carolyn L, Poutanen, Matti, Odermatt, Alex, Cox, Roger D, Tomlinson, Jeremy W
Published in Journal of endocrinology (13.04.2022)
Published in Journal of endocrinology (13.04.2022)
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Journal Article
Cardiac mitochondrial function depends on BUD23 mediated ribosome programming
Baxter, Matthew, Voronkov, Maria, Poolman, Toryn, Galli, Gina, Pinali, Christian, Goosey, Laurence, Knight, Abigail, Krakowiak, Karolina, Maidstone, Robert, Iqbal, Mudassar, Zi, Min, Prehar, Sukhpal, Cartwright, Elizabeth J, Gibbs, Julie, Matthews, Laura C, Adamson, Antony D, Humphreys, Neil E, Rebelo-Guiomar, Pedro, Minczuk, Michal, Bechtold, David A, Loudon, Andrew, Ray, David
Published in eLife (15.01.2020)
Published in eLife (15.01.2020)
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Journal Article
Pin1 promotes GR transactivation by enhancing recruitment to target genes
Poolman, Toryn M, Farrow, Stuart N, Matthews, Laura, Loudon, Andrew S, Ray, David W
Published in Nucleic acids research (01.10.2013)
Published in Nucleic acids research (01.10.2013)
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Journal Article
A role for mitochondrial oxidants in stress-induced premature senescence of human vascular smooth muscle cells
Mistry, Yogita, Poolman, Toryn, Williams, Bryan, Herbert, Karl E
Published in Redox biology (01.01.2013)
Published in Redox biology (01.01.2013)
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Journal Article