Effects of Drug–Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody–Maytansinoid Conjugates
Sun, Xiuxia, Ponte, Jose F, Yoder, Nicholas C, Laleau, Rassol, Coccia, Jennifer, Lanieri, Leanne, Qiu, Qifeng, Wu, Rui, Hong, Erica, Bogalhas, Megan, Wang, Lintao, Dong, Ling, Setiady, Yulius, Maloney, Erin K, Ab, Olga, Zhang, Xiaoyan, Pinkas, Jan, Keating, Thomas A, Chari, Ravi, Erickson, Hans K, Lambert, John M
Published in Bioconjugate chemistry (17.05.2017)
Published in Bioconjugate chemistry (17.05.2017)
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Phase 1 dose‐escalation study of mirvetuximab soravtansine (IMGN853), a folate receptor α‐targeting antibody‐drug conjugate, in patients with solid tumors
Moore, Kathleen N., Borghaei, Hossein, O'Malley, David M., Jeong, Woondong, Seward, Shelly M., Bauer, Todd M., Perez, Raymond P., Matulonis, Ursula A., Running, Kelli L., Zhang, Xiaoyan, Ponte, Jose F., Ruiz‐Soto, Rodrigo, Birrer, Michael J.
Published in Cancer (15.08.2017)
Published in Cancer (15.08.2017)
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A review of mirvetuximab soravtansine in the treatment of platinum-resistant ovarian cancer
Moore, Kathleen N, Martin, Lainie P, O'Malley, David M, Matulonis, Ursula A, Konner, Jason A, Vergote, Ignace, Ponte, Jose F, Birrer, Michael J
Published in Future oncology (London, England) (01.01.2018)
Published in Future oncology (London, England) (01.01.2018)
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Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody-Drug Conjugates to Increase In Vivo Efficacy
Ponte, Jose F, Lanieri, Leanne, Khera, Eshita, Laleau, Rassol, Ab, Olga, Espelin, Christopher, Kohli, Neeraj, Matin, Bahar, Setiady, Yulius, Miller, Michael L, Keating, Thomas A, Chari, Ravi, Pinkas, Jan, Gregory, Richard, Thurber, Greg M
Published in Molecular cancer therapeutics (01.01.2021)
Published in Molecular cancer therapeutics (01.01.2021)
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Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha–Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models
Ponte, Jose F, Ab, Olga, Lanieri, Leanne, Lee, Jenny, Coccia, Jennifer, Bartle, Laura M, Themeles, Marian, Zhou, Yinghui, Pinkas, Jan, Ruiz-Soto, Rodrigo
Published in Neoplasia (New York, N.Y.) (01.12.2016)
Published in Neoplasia (New York, N.Y.) (01.12.2016)
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Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder
Abdolmaleky, Hamid Mostafavi, Cheng, Kuang-hung, Faraone, Stephen V., Wilcox, Marsha, Glatt, Stephen J., Gao, Fangming, Smith, Cassandra L., Shafa, Rahim, Aeali, Batol, Carnevale, Julie, Pan, Hongjie, Papageorgis, Panagiotis, Ponte, Jose F., Sivaraman, Vadivelu, Tsuang, Ming T., Thiagalingam, Sam
Published in Human molecular genetics (01.11.2006)
Published in Human molecular genetics (01.11.2006)
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Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-Linked Antibody–Maytansinoid Conjugates
Ponte, Jose F, Sun, Xiuxia, Yoder, Nicholas C, Fishkin, Nathan, Laleau, Rassol, Coccia, Jennifer, Lanieri, Leanne, Bogalhas, Megan, Wang, Lintao, Wilhelm, Sharon, Widdison, Wayne, Pinkas, Jan, Keating, Thomas A, Chari, Ravi, Erickson, Hans K, Lambert, John M
Published in Bioconjugate chemistry (20.07.2016)
Published in Bioconjugate chemistry (20.07.2016)
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The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models
Hicks, Stuart W., Lai, Katharine C., Gavrilescu, L. Cristina, Yi, Yong, Sikka, Surina, Shah, Prerak, Kelly, Meghan E., Lee, Jenny, Lanieri, Leanne, Ponte, Jose F., Sloss, Callum M., Romanelli, Angela
Published in Neoplasia (New York, N.Y.) (01.09.2017)
Published in Neoplasia (New York, N.Y.) (01.09.2017)
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A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody-Drug Conjugates (ADCs)
Miller, Michael L, Shizuka, Manami, Wilhelm, Alan, Salomon, Paulin, Reid, Emily E, Lanieri, Leanne, Sikka, Surina, Maloney, Erin K, Harvey, Lauren, Qiu, Qifeng, Archer, Katie E, Bai, Chen, Vitharana, Dilrukshi, Harris, Luke, Singh, Rajeeva, Ponte, Jose F, Yoder, Nicholas C, Kovtun, Yelena, Lai, Katharine C, Ab, Olga, Pinkas, Jan, Keating, Thomas A, Chari, Ravi V J
Published in Molecular cancer therapeutics (01.03.2018)
Published in Molecular cancer therapeutics (01.03.2018)
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In Vitro and In Vivo Activity of IMGN853, an Antibody-Drug Conjugate Targeting Folate Receptor Alpha Linked to DM4, in Biologically Aggressive Endometrial Cancers
Altwerger, Gary, Bonazzoli, Elena, Bellone, Stefania, Egawa-Takata, Tomomi, Menderes, Gulden, Pettinella, Francesca, Bianchi, Anna, Riccio, Francesco, Feinberg, Jacqueline, Zammataro, Luca, Han, Chanhee, Yadav, Ghanshyam, Dugan, Katherine, Morneault, Ashley, Ponte, Jose F, Buza, Natalia, Hui, Pei, Wong, Serena, Litkouhi, Babak, Ratner, Elena, Silasi, Dan-Arin, Huang, Gloria S, Azodi, Masoud, Schwartz, Peter E, Santin, Alessandro D
Published in Molecular cancer therapeutics (01.05.2018)
Published in Molecular cancer therapeutics (01.05.2018)
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Global sharing, local innovation: Four schools, four countries, one curriculum
Castelo-Branco, Luís, Finucane, Paul, Marvão, Pedro, McCrorie, Peter, Ponte, José, Worley, Paul
Published in Medical teacher (01.12.2016)
Published in Medical teacher (01.12.2016)
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Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs)
Reid, Emily E., Archer, Katie E., Shizuka, Manami, McShea, Molly A., Maloney, Erin K., Ab, Olga, Lanieri, Leanne, Wilhelm, Alan, Ponte, Jose F., Yoder, Nicholas C., Chari, Ravi V.J., Miller, Michael L.
Published in Bioorganic & medicinal chemistry letters (01.09.2019)
Published in Bioorganic & medicinal chemistry letters (01.09.2019)
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Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing
Widdison, Wayne C, Ponte, Jose F, Coccia, Jennifer A, Lanieri, Leanne, Setiady, Yulius, Dong, Ling, Skaletskaya, Anna, Hong, E. Erica, Wu, Rui, Qiu, Qifeng, Singh, Rajeeva, Salomon, Paulin, Fishkin, Nathan, Harris, Luke, Maloney, Erin K, Kovtun, Yelena, Veale, Karen, Wilhelm, Sharon D, Audette, Charlene A, Costoplus, Juliet A, Chari, Ravi V. J
Published in Bioconjugate chemistry (18.11.2015)
Published in Bioconjugate chemistry (18.11.2015)
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Characteristics and management of Susac syndrome in an emergent country: a multi-center case series from Brazil
Santiago, Igor Bessa, Araújo, Abraão Lazaro Meneses, Nóbrega, Ivna Lacerda Pereira, Silva, Walisson Grangeiro Bringel, Mendes, Lucas Silvestre, Ponte, José Israel Araújo, Dias, Daniel Aguiar, de Castro, José Daniel Vieira, Cunha, Francisco Marcos Bezerra, Sobreira-Neto, Manoel Alves, Braga-Neto, Pedro, Martins, Gabriela Joca, de Aragão, Ricardo Evangelista Marrocos, Silva, Guilherme Diogo, Nóbrega, Paulo Ribeiro
Published in Neurological sciences (01.11.2022)
Published in Neurological sciences (01.11.2022)
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Differential DNA Hypermethylation of Critical Genes Mediates the Stage-Specific Tobacco Smoke-Induced Neoplastic Progression of Lung Cancer
Russo, Andrea L, Thiagalingam, Arunthathi, Pan, Hongjie, Califano, Joseph, Cheng, Kuang-hung, Ponte, Jose F, Chinnappan, Dharmaraj, Nemani, Pratima, Sidransky, David, Thiagalingam, Sam
Published in Clinical cancer research (01.04.2005)
Published in Clinical cancer research (01.04.2005)
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Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing
Costoplus, Juliet A, Veale, Karen H, Qiu, Qifeng, Ponte, Jose F, Lanieri, Leanne, Setiady, Yulius, Dong, Ling, Skaletskaya, Anna, Bartle, Laura M, Salomon, Paulin, Wu, Rui, Maloney, Erin K, Kovtun, Yelena V, Ab, Olga, Lai, Kate, Chari, Ravi V. J, Widdison, Wayne C
Published in ACS medicinal chemistry letters (10.10.2019)
Published in ACS medicinal chemistry letters (10.10.2019)
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Leveraging PET to image folate receptor α therapy of an antibody-drug conjugate
Brand, Christian, Sadique, Ahmad, Houghton, Jacob L., Gangangari, Kishore, Ponte, Jose F., Lewis, Jason S., Pillarsetty, Naga Vara Kishore, Konner, Jason A., Reiner, Thomas
Published in EJNMMI research (28.08.2018)
Published in EJNMMI research (28.08.2018)
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Blepharoplasty with canthopexy in a patient with cutis laxa: A case report
Alencar Filho, Jose Isnack Ponte de, Frota-Júnior, José Alberto Guilherme, Cardoso, Guilherme Pinho, Muniz, Vitor de Vasconcellos, Alcântara, Fernando Soares de, Pessoa, Salustiano Gomes de Pinho
Published in Revista Brasileira de cirurgia plástica (2024)
Published in Revista Brasileira de cirurgia plástica (2024)
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Synthesis of Highly Potent N‑10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody–Drug Conjugates (ADCs)
Archer, Katie E, Reid, Emily E, Shizuka, Manami, Woods, James, Harris, Luke, Maloney, Erin K, Bartle, Laura M, Ab, Olga, Wilhelm, Alan, Setiady, Yulius, Ponte, Jose F, Singh, Rajeeva, Keating, Thomas A, Chari, Ravi V. J, Miller, Michael L
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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