Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro – in vivo extrapolation of hepatic clearance
Palacharla, Raghava Choudary, Uthukam, Venkatesham, Manoharan, Arunkumar, Ponnamaneni, Ranjith Kumar, Padala, Nagasurya Prakash, Boggavarapu, Rajesh Kumar, Bhyrapuneni, Gopinadh, Ajjala, Devender Reddy, Nirogi, Ramakrishna
Published in European journal of pharmaceutical sciences (01.04.2017)
Published in European journal of pharmaceutical sciences (01.04.2017)
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Journal Article
Chemical inhibitors of CYP450 enzymes in liver microsomes: combining selectivity and unbound fractions to guide selection of appropriate concentration in phenotyping assays
Nirogi, Ramakrishna, Palacharla, Raghava Choudary, Uthukam, Venkatesham, Manoharan, Arunkumar, Srikakolapu, Surya Rao, Kalaikadhiban, Ilayaraja, Boggavarapu, Rajesh Kumar, Ponnamaneni, Ranjith Kumar, Ajjala, Devender Reddy, Bhyrapuneni, Gopinadh
Published in Xenobiotica (01.02.2015)
Published in Xenobiotica (01.02.2015)
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Journal Article
Identification of a suitable and selective inhibitor towards aldehyde oxidase catalyzed reactions
Nirogi, Ramakrishna, Kandikere, Vishwottam, Palacharla, Raghava Choudary, Bhyrapuneni, Gopinadh, Kanamarlapudi, Vijaya Bhargava, Ponnamaneni, Ranjith Kumar, Manoharan, Arun Kumar
Published in Xenobiotica (01.03.2014)
Published in Xenobiotica (01.03.2014)
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Journal Article
Effect of Dimethyl Sulfoxide on In Vitro Cytochrome P4501A2 Mediated Phenacetin O-Deethylation in Human Liver Microsomes
NIROGI, Ramakrishna, KANDIKERE, Vishwottam, BHYRAPUNENI, Gopinadh, RANJITH KUMAR PONNAMANENI, RAGHAVA CHOUDARY PALACHARLA, MANOHARAN, Arunkumar
Published in Drug metabolism and disposition (01.11.2011)
Published in Drug metabolism and disposition (01.11.2011)
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Journal Article
Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims
Palacharla, Raghava Choudary, Nirogi, Ramakrishna, Uthukam, Venkatesham, Manoharan, Arunkumar, Ponnamaneni, Ranjith Kumar, Kalaikadhiban, Ilayaraja
Published in Xenobiotica (03.07.2018)
Published in Xenobiotica (03.07.2018)
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Journal Article
Methoxsalen as an in vitro phenotyping tool in comparison with 1-aminobenzotriazole
Palacharla, Raghava Choudary, Molgara, Parusharamulu, Panthangi, Hanumanth Rao, Boggavarapu, Rajesh Kumar, Manoharan, Arun Kumar, Ponnamaneni, Ranjith Kumar, Ajjala, Devender Reddy, Nirogi, Ramakrishna
Published in Xenobiotica (01.02.2019)
Published in Xenobiotica (01.02.2019)
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Journal Article
Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction
Nirogi, Ramakrishna, Palacharla, Raghava Choudary, Mohammed, Abdul Rasheed, Manoharan, Arunkumar, Ponnamaneni, Ranjith kumar, Bhyrapuneni, Gopinadh
Published in Chemico-biological interactions (25.03.2015)
Published in Chemico-biological interactions (25.03.2015)
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Journal Article
Evaluation of methoxsalen as a PAN-CYP450 direct and time dependent inhibitor in human liver microsomes: Comparison with ABT as a tool for in vitro phenotyping studies
Palacharla, Raghava Choudary, Molgara, Parusharamulu, Manoharan, Arun Kumar, Kalaikadhiban, Ilayaraja, Ponnamaneni, Ranjith kumar, Bhyrapuneni, Gopinadh, Nirogi, Ramakrishna
Published in Drug metabolism and pharmacokinetics (01.01.2018)
Published in Drug metabolism and pharmacokinetics (01.01.2018)
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Journal Article
5-ht6 antagonist SUVN-502 potentiates the procognitive and neurochemical effects of donepezil and memantine
Jayarajan, Pradeep, Abraham, Renny, Bhyrapuneni, Gopinadh, Benade, Vijay S, Ayyanki, Ganesh, Medapati, Rajesh Babu, Venkateshwarlu, Ravirala, Muddana, Nageswararao, Ponnamaneni, Ranjith Kumar, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
P1‐302: 5‐ht 6 antagonist SUVN‐502 potentiates the procognitive and neurochemical effects of donepezil and memantine
Jayarajan, Pradeep, Abraham, Renny, Bhyrapuneni, Gopinadh, Benade, Vijay S., Ayyanki, Ganesh, Medapati, Rajesh Babu, Venkateshwarlu, Ravirala, Muddana, Nageswararao, Ponnamaneni, Ranjith Kumar, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
P1‐311: The 5‐ht 6 antagonist SUVN‐502 potentiates the effects of acetylcholinesterase inhibitors on extracellular acetylcholine levels and in animal models of cognition
Bhyrapuneni, Gopinadh, Benade, Vijay S., Kamuju, Venkatesh, Ponnamaneni, Ranjith Kumar, Irappanavar, Shantaveer M., Jayarajan, Pradeep, Abraham, Renny, Kota, Laxman, Saraf, Sangram Keshari, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
P1‐311: The 5‐ht6 antagonist SUVN‐502 potentiates the effects of acetylcholinesterase inhibitors on extracellular acetylcholine levels and in animal models of cognition
Bhyrapuneni, Gopinadh, Benade, Vijay S., Kamuju, Venkatesh, Ponnamaneni, Ranjith Kumar, Irappanavar, Shantaveer M., Jayarajan, Pradeep, Abraham, Renny, Kota, Laxman, Saraf, Sangram Keshari, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
P1‐302: 5‐ht6 antagonist SUVN‐502 potentiates the procognitive and neurochemical effects of donepezil and memantine
Jayarajan, Pradeep, Abraham, Renny, Bhyrapuneni, Gopinadh, Benade, Vijay S., Ayyanki, Ganesh, Medapati, Rajesh Babu, Venkateshwarlu, Ravirala, Muddana, Nageswararao, Ponnamaneni, Ranjith Kumar, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
The 5-ht6 antagonist SUVN-502 potentiates the effects of acetylcholinesterase inhibitors on extracellular acetylcholine levels and in animal models of cognition
Bhyrapuneni, Gopinadh, Benade, Vijay S, Kamuju, Venkatesh, Ponnamaneni, Ranjith Kumar, Irappanavar, Shantaveer M, Jayarajan, Pradeep, Abraham, Renny, Kota, Laxman, Saraf, Sangram Keshari, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2015)
Published in Alzheimer's & dementia (01.07.2015)
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Journal Article
In vivo receptor occupancy assay of histamine H3 receptor antagonist in rats using non-radiolabeled tracer
Nirogi, Ramakrishna, Kandikere, Vishwottam, Bhyrapuneni, Gopinadh, Muddana, Nageswararao, Saralaya, Ramanatha, Ponnamaneni, Ranjith Kumar, Manoharan, Arun Kumar
Published in Journal of pharmacological and toxicological methods (01.05.2012)
Published in Journal of pharmacological and toxicological methods (01.05.2012)
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Journal Article
P3‐379: The novel and selective α4β2 agonist, SUVN‐911 enhances acetylcholine levels in frontoparietal cortex
Bhyrapuneni, Gopinadh, Muddana, Nageshwara Rao, Kandikere, Vishwottam, Benade, Vijay, Ponnamaneni, Ranjith Kumar, Mudigonda, Koteshwara, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
P3‐379: The novel and selective α 4 β 2 agonist, SUVN‐911 enhances acetylcholine levels in frontoparietal cortex
Bhyrapuneni, Gopinadh, Muddana, Nageshwara Rao, Kandikere, Vishwottam, Benade, Vijay, Ponnamaneni, Ranjith Kumar, Mudigonda, Koteshwara, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
The novel and selective α4β2 agonist, SUVN-911 enhances acetylcholine levels in frontoparietal cortex
Bhyrapuneni, Gopinadh, Muddana, Nageshwara Rao, Kandikere, Vishwottam, Benade, Vijay, Ponnamaneni, Ranjith Kumar, Mudigonda, Koteshwara, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Journal Article
The novel and selective α4 β2 agonist, SUVN-911 enhances acetylcholine levels in frontoparietal cortex
Bhyrapuneni, Gopinadh, Muddana, Nageshwara Rao, Kandikere, Vishwottam, Benade, Vijay, Ponnamaneni, Ranjith Kumar, Mudigonda, Koteshwara, Nirogi, Ramakrishna
Published in Alzheimer's & dementia (2010)
Published in Alzheimer's & dementia (2010)
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Journal Article