Search Results - "Ponesimod" :: K.UTB vyhledávací portál

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Ponesimod, a selective sphingosine 1-phosphate (S1P1) receptor modulator for autoimmune diseases: review of clinical pharmacokinetics and drug disposition

by Dash, Ranjeet Prasad, Rais, Rana, Srinivas, Nuggehally R.
Published in Xenobiotica (04.05.2018)

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Multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ponesimod, an S1P1 receptor modulator: favorable impact of dose up-titration

by Brossard, P, Scherz, M, Halabi, A, Maatouk, H, Krause, A, Dingemanse, J
Published in Journal of clinical pharmacology (01.02.2014)

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Three different up-titration regimens of ponesimod, an S1P1 receptor modulator, in healthy subjects

by Scherz, Michael W, Brossard, Patrick, D'Ambrosio, Daniele, Ipek, Murat, Dingemanse, Jasper
Published in Journal of clinical pharmacology (01.06.2015)

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Clinical pharmacology of ponesimod, a selective S1P1 receptor modulator, after uptitration to supratherapeutic doses in healthy subjects

by Hoch, M., D’Ambrosio, D., Wilbraham, D., Brossard, P., Dingemanse, J.
Published in European journal of pharmaceutical sciences (15.10.2014)

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Population pharmacokinetics of ponesimod and its primary metabolites in healthy and organ-impaired subjects

by Lott, Dominik, Krause, Andreas, Dingemanse, Jasper, Lehr, Thorsten
Published in European journal of pharmaceutical sciences (30.06.2016)

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Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes

by Lott, Dominik, Krause, Andreas, Seemayer, Christian A., Strasser, Daniel S., Dingemanse, Jasper, Lehr, Thorsten
Published in Pharmaceutical research (01.03.2017)

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Biocomparison of THREE formulations of the S1P1receptor modulator ponesimod in healthy subjects

by Juif, P-E, Hoch, M, D'Ambrosio, D, Dingemanse, J
Published in Clinical therapeutics (01.08.2015)

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Biocomparison of THREE formulations of the S1P1 receptor modulator ponesimod in healthy subjects

by Juif, P.-E., Hoch, M., D’Ambrosio, D., Dingemanse, J.
Published in Clinical therapeutics (01.08.2015)

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Absolute Bioavailability of Ponesimod, a Selective S1P1 Receptor Modulator, in Healthy Male Subjects

by Boehler, Margaux, Juif, Pierre-Eric, Hoch, Matthias, Dingemanse, Jasper
Published in European journal of drug metabolism and pharmacokinetics (01.02.2017)

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Modeling the Effect of the Selective S1P.sub.1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes

by Lott, Dominik, Krause, Andreas, Seemayer, Christian A, Strasser, Daniel S, Dingemanse, Jasper, Lehr, Thorsten
Published in Pharmaceutical research (01.03.2017)

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Effect of Ponesimod, a Selective S1P1 Receptor Modulator, on the QT Interval in Healthy Individuals

by Hoch, Matthias, Darpo, Borje, Brossard, Patrick, Zhou, Meijian, Stoltz, Randall, Dingemanse, Jasper
Published in Basic & clinical pharmacology & toxicology (01.05.2015)

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Effects of multiple-dose ponesimod, a selective S1P1 receptor modulator, on lymphocyte subsets in healthy humans

by Jurcevic, Stipo, Pierre-Eric Juif, Hamid, Colleen, Greenlaw, Roseanna, D'Ambrosio, Daniele, Dingemanse, Jasper
Published in Drug design, development and therapy (2017)

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Biocomparison of Three Formulations of the S1P1 Receptor Modulator Ponesimod in Healthy Subjects

by Juif, Pierre-Eric, Hoch, Matthias, D’Ambrosio, Daniele, Dingemanse, Jasper
Published in Drugs in R&D (01.06.2015)

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Modeling the Effect of the Selective S1P^sub 1^ Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes

by Lott, Dominik, Krause, Andreas, Seemayer, Christian A, Strasser, Daniel S, Dingemanse, Jasper, Lehr, Thorsten
Published in Pharmaceutical research (01.03.2017)

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Mass balance, pharmacokinetics and metabolism of the selective S1P1 receptor modulator ponesimod in humans

by Reyes, Maribel, Hoch, Matthias, Brossard, Patrick, Wagner-Redeker, Winfried, Miraval, Tommaso, Dingemanse, Jasper
Published in Xenobiotica (01.02.2015)

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Pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator, in the first‐in‐human study

by Brossard, Patrick, Derendorf, Hartmut, Xu, Jian, Maatouk, Haidar, Halabi, Atef, Dingemanse, Jasper
Published in British journal of clinical pharmacology (01.12.2013)

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Impact of Demographics, Organ Impairment, Disease, Formulation, and Food on the Pharmacokinetics of the Selective S1P^sub 1^ Receptor Modulator Ponesimod Based on 13 Clinical Studies

by Lott, Dominik, Lehr, Thorsten, Dingemanse, Jasper, Krause, Andreas
Published in Clinical pharmacokinetics (01.04.2017)

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Effects of Ethnicity and Sex on the Pharmacokinetics and Pharmacodynamics of the Selective Sphingosine-1-Phosphate Receptor 1 Modulator Ponesimod: A Clinical Study in Japanese and Caucasian Subjects

by Reyes, Maribel, Hoch, Matthias, Brossard, Patrick, Dingemanse, Jasper
Published in Pharmacology (01.01.2014)

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Differential effects of ponesimod, a selective S1P1 receptor modulator, on blood-circulating human T cell subpopulations

by D'Ambrosio, Daniele, Steinmann, Jörg, Brossard, Patrick, Dingemanse, Jasper
Published in Immunopharmacology and immunotoxicology (01.02.2015)

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Oc015—Up-Titration Study With Ponesimod, A Selective S1p1 Receptor Modulator, To Assess Its Maximum Tolerated Dose In Healthy Subjects

by Hoch, M., D'Ambrosio, D., Wilbraham, D., Brossard, P., Dingemanse, J.
Published in Clinical therapeutics (01.08.2013)

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