Curcumin Promotes Autophagic Survival of a Subset of Colon Cancer Stem Cells, Which Are Ablated by DCLK1-siRNA
KANTARA, Carla, O'CONNELL, Malaney, SARKAR, Shubhashish, MOYA, Stephanie, ULLRICH, Robert, SINGH, Pomila
Published in Cancer research (Chicago, Ill.) (01.05.2014)
Published in Cancer research (Chicago, Ill.) (01.05.2014)
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Inhibition of LEF1-Mediated DCLK1 by Niclosamide Attenuates Colorectal Cancer Stemness
Park, So-Yeon, Kim, Ji-Young, Choi, Jang-Hyun, Kim, Jee-Heun, Lee, Choong-Jae, Singh, Pomila, Sarkar, Shubhashish, Baek, Jeong-Heum, Nam, Jeong-Seok
Published in Clinical cancer research (15.02.2019)
Published in Clinical cancer research (15.02.2019)
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CD90+ stromal cells are the major source of IL‐6, which supports cancer stem‐like cells and inflammation in colorectal cancer
Huynh, Phuong T., Beswick, Ellen J., Coronado, Yun A., Johnson, Paul, O'Connell, Malaney R., Watts, Tammara, Singh, Pomila, Qiu, Suimin, Morris, Katherine, Powell, Don W., Pinchuk, Irina V.
Published in International journal of cancer (15.04.2016)
Published in International journal of cancer (15.04.2016)
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Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis
Kantara, Carla, O'Connell, Malaney Ravae, Luthra, Gurinder, Gajjar, Aakash, Sarkar, Shubhashish, Ullrich, Robert Leo, Singh, Pomila
Published in Laboratory investigation (01.01.2015)
Published in Laboratory investigation (01.01.2015)
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Real-time Kinetics of High-mobility Group Box 1 (HMGB1) Oxidation in Extracellular Fluids Studied by in Situ Protein NMR Spectroscopy
Zandarashvili, Levani, Sahu, Debashish, Lee, Kwanbok, Lee, Yong Sun, Singh, Pomila, Rajarathnam, Krishna, Iwahara, Junji
Published in The Journal of biological chemistry (26.04.2013)
Published in The Journal of biological chemistry (26.04.2013)
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Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications
O’Connell, Malaney R., Sarkar, Shubhashish, Luthra, Gurinder K., Okugawa, Yoshinaga, Toiyama, Yuji, Gajjar, Aakash H., Qiu, Suimin, Goel, Ajay, Singh, Pomila
Published in Scientific reports (08.10.2015)
Published in Scientific reports (08.10.2015)
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FOXD3 Regulates CSC Marker, DCLK1-S, and Invasive Potential: Prognostic Implications in Colon Cancer
Sarkar, Shubhashish, O'Connell, Malaney R, Okugawa, Yoshinaga, Lee, Brian S, Toiyama, Yuji, Kusunoki, Masato, Daboval, Robert D, Goel, Ajay, Singh, Pomila
Published in Molecular cancer research (01.12.2017)
Published in Molecular cancer research (01.12.2017)
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Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model
Andey, Terrick, Marepally, Srujan, Patel, Apurva, Jackson, Tanise, Sarkar, Shubhashish, O'Connell, Malaney, Reddy, Rakesh C, Chellappan, Srikumar, Singh, Pomila, Singh, Mandip
Published in Journal of controlled release (28.06.2014)
Published in Journal of controlled release (28.06.2014)
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Distinct Compartmentalization of NF-κB Activity in Crypt and Crypt-Denuded Lamina Propria Precedes and Accompanies Hyperplasia and/or Colitis following Bacterial Infection
CHANDRAKESAN, Parthasarathy, AHMED, Ishfaq, CHINTHALAPALLY, Anisha, SINGH, Pomila, AWASTHI, Shanjana, ANANT, Shrikant, UMAR, Shahid
Published in Infection and Immunity (01.02.2012)
Published in Infection and Immunity (01.02.2012)
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Mice overexpressing progastrin are predisposed for developing aberrant colonic crypt foci in response to AOM
Singh, P, Velasco, M, Given, R, Wargovich, M, Varro, A, Wang, T C
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2000)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.03.2000)
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Abstract 5242: Differential, dose-dependent, effects of curcumin/analogs, on long (L) versus short (S) isoforms of a cancer stem cell marker, DCLK1, in colon and pancreatic cancer cells: biological impact
Sarkar, Shubhashish, Connell, Malaney O., Singh, Pomila
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 2817: Dietary chemopreventive agent (curcumin), hypomethylates 5′ promoter of DCLK1 gene in human colon cancer cells and restores expression of long isoform of DCLK1
Sarkar, Shubhashish, O'Connell, Malaney, singh, Pomila
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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