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Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
Fong, Peter C, Boss, David S, Yap, Timothy A, Tutt, Andrew, Wu, Peijun, Mergui-Roelvink, Marja, Mortimer, Peter, Swaisland, Helen, Lau, Alan, O'Connor, Mark J, Ashworth, Alan, Carmichael, James, Kaye, Stan B, Schellens, Jan H.M, de Bono, Johann S
Published in The New England journal of medicine (09.07.2009)
Published in The New England journal of medicine (09.07.2009)
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Metabolite profiles and mass balance of fuzuloparib, a novel poly (ADP‐ribose) polymerase inhibitor, in subjects with advanced solid cancers
Bian, Yicong, Meng, Jian, Ma, Sheng, Li, Guangze, Wang, Yuya, Li, Shaorong, Liu, Linsheng, Huang, Chenrong, Zhang, Hua, Zhong, Dafang, Miao, Liyan
Published in British journal of clinical pharmacology (01.07.2022)
Published in British journal of clinical pharmacology (01.07.2022)
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PET of Poly (ADP-Ribose) Polymerase Activity in Cancer: Preclinical Assessment and First In-Human Studies
Michel, Loren S., Dyroff, Samantha, Brooks, Frank J., Spayd, Katherine J., Lim, Sora, Engle, Jacquelyn T., Phillips, Sharon, Tan, Benjamin, Wang-Gillam, Andrea, Bognar, Christopher, Chu, Wenhua, Zhou, Dong, Mach, Robert H., Laforest, Richard, Chen, Delphine L.
Published in Radiology (01.02.2017)
Published in Radiology (01.02.2017)
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Poly (ADP‐ribose) polymerase‐1 is a key mediator of liver inflammation and fibrosis
Mukhopadhyay, Partha, Rajesh, Mohanraj, Cao, Zongxian, Horváth, Béla, Park, Ogyi, Wang, Hua, Erdelyi, Katalin, Holovac, Eileen, Wang, Yuping, Liaudet, Lucas, Hamdaoui, Nabila, Lafdil, Fouad, Haskó, György, Szabo, Csaba, Boulares, A. Hamid, Gao, Bin, Pacher, Pal
Published in Hepatology (Baltimore, Md.) (01.05.2014)
Published in Hepatology (Baltimore, Md.) (01.05.2014)
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Regulation of Myofibroblast Differentiation by Poly(ADP-Ribose) Polymerase 1
Hu, Biao, Wu, Zhe, Hergert, Polla, Henke, Craig A., Bitterman, Peter B., Phan, Sem H.
Published in The American journal of pathology (01.01.2013)
Published in The American journal of pathology (01.01.2013)
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Modulation of Poly ADP Ribose Polymerase (PARP) Levels and Activity by Alcohol Binge-Like Drinking in Male Mice
Vallerini, Gian Paolo, Cheng, You-Hong, Chase, Kayla A., Sharma, Rajiv P., Kusumo, Handojo, Khakhkhar, Shivani, Feinstein, Douglas L., Guizzetti, Marina, Gavin, David P.
Published in Neuroscience (10.11.2020)
Published in Neuroscience (10.11.2020)
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PARP Inhibitors in Ovarian Cancer
Mittica, Gloria, Ghisoni, Eleonora, Giannone, Gaia, Genta, Sofia, Aglietta, Massimo, Sapino, Anna, Valabrega, Giorgio
Published in Recent patents on anti-cancer drug discovery (01.01.2018)
Published in Recent patents on anti-cancer drug discovery (01.01.2018)
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Aryl Hydrocarbon Receptor Activation by Dioxin Targets Phosphoenolpyruvate Carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-inducible Poly(ADP-ribose) Polymerase (TiPARP)
Diani-Moore, Silvia, Zhang, Sheng, Ram, Payal, Rifkind, Arleen B.
Published in The Journal of biological chemistry (26.07.2013)
Published in The Journal of biological chemistry (26.07.2013)
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Regulation of Epstein-Barr Virus OriP Replication by Poly(ADP-Ribose) Polymerase 1
Tempera, Italo, Deng, Zhong, Atanasiu, Constandache, Chen, Chi-Ju, D'Erme, Maria, Lieberman, Paul M.
Published in Journal of Virology (01.05.2010)
Published in Journal of Virology (01.05.2010)
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PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination
Bryant, Helen E, Petermann, Eva, Schultz, Niklas, Jemth, Ann-Sofie, Loseva, Olga, Issaeva, Natalia, Johansson, Fredrik, Fernandez, Serena, McGlynn, Peter, Helleday, Thomas
Published in The EMBO journal (02.09.2009)
Published in The EMBO journal (02.09.2009)
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1060TiPRandomized, phase Ib/II study of M6620 + avelumab + carboplatin vs standard care (sc) in patients (pts) with platinum-sensitive poly (ADP-ribose) polymerase inhibitor-(PARPi)-resistant ovarian cancer
Banerjee, S, Vergotte, I, Colombo, N, Barve, M, Grisham, R, Mehr, K T, Falk, M, Beier, F, Hennessy, M, Schroeder, A, Birrer, M
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells
Drel, Viktor R., Pacher, Pal, Stevens, Martin J., Obrosova, Irina G.
Published in Free radical biology & medicine (15.04.2006)
Published in Free radical biology & medicine (15.04.2006)
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PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis
Mukhopadhyay, Partha, Horváth, Béla, Rajesh, Mohanraj, Varga, Zoltán V., Gariani, Karim, Ryu, Dongryeol, Cao, Zongxian, Holovac, Eileen, Park, Ogyi, Zhou, Zhou, Xu, Ming-Jiang, Wang, Wei, Godlewski, Grzegorz, Paloczi, Janos, Nemeth, Balazs Tamas, Persidsky, Yuri, Liaudet, Lucas, Haskó, György, Bai, Peter, Boulares, A. Hamid, Auwerx, Johan, Gao, Bin, Pacher, Pal
Published in Journal of hepatology (01.03.2017)
Published in Journal of hepatology (01.03.2017)
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Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance
Johnson, Neil, Johnson, Shawn F., Yao, Wei, Li, Yu-Chen, Choi, Young-Eun, Bernhardy, Andrea J., Wang, Yifan, Capelletti, Marzia, Sarosiek, Kristopher A., Moreau, Lisa A., Chowdhury, Dipanjan, Wickramanayake, Anneka, Harrell, Maria I., Liu, Joyce F., D'Andrea, Alan D., Miron, Alexander, Swisher, Elizabeth M., Shapiro, Geoffrey I.
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2013)
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31 Response to chemotherapy after treatment with a poly(ADP-ribose) polymerase inhibitor for patients with epithelial ovarian cancer
Marjon, Nicole, Kay, Allison, Papa, Franceed Horton, Tucker, Lue-Yen, Bookman, Michael A.A.
Published in Gynecologic oncology reports (01.12.2022)
Published in Gynecologic oncology reports (01.12.2022)
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1060TiP - Randomized, phase Ib/II study of M6620 + avelumab + carboplatin vs standard care (sc) in patients (pts) with platinum-sensitive poly (ADP-ribose) polymerase inhibitor-(PARPi)-resistant ovarian cancer
Banerjee, S., Vergotte, I., Colombo, N., Barve, M., Grisham, R., Mehr, K.T., Falk, M., Beier, F., Hennessy, M., Schroeder, A., Birrer, M.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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