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Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis and poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets
Mavian, Carla, Ramirez-Mata, Andrea S., Dollar, James Jarad, Nolan, David J., Cash, Melanie, White, Kevin, Rich, Shannan N., Magalis, Brittany Rife, Marini, Simone, Prosperi, Mattia C. F., Amador, David Moraga, Riva, Alberto, Williams, Kenneth C., Salemi, Marco
Published in Journal of neurovirology (01.02.2021)
Published in Journal of neurovirology (01.02.2021)
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Second-line olaparib maintenance therapy is associated with poor response to subsequent chemotherapy in BRCA1/2-mutated epithelial ovarian cancer: A multicentre retrospective study
Park, Junsik, Kim, Se Ik, Jeong, Soo Young, Kim, Yup, Bookman, Michael A., Kim, Jae-Weon, Kim, Byoung-Gie, Lee, Jung-Yun
Published in Gynecologic oncology (01.04.2022)
Published in Gynecologic oncology (01.04.2022)
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NAD and the aging process: Role in life, death and everything in between
Chini, Claudia C.S., Tarragó, Mariana G., Chini, Eduardo N.
Published in Molecular and cellular endocrinology (05.11.2017)
Published in Molecular and cellular endocrinology (05.11.2017)
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Poly (ADP‐ribose) polymerase‐1 is a key mediator of liver inflammation and fibrosis
Mukhopadhyay, Partha, Rajesh, Mohanraj, Cao, Zongxian, Horváth, Béla, Park, Ogyi, Wang, Hua, Erdelyi, Katalin, Holovac, Eileen, Wang, Yuping, Liaudet, Lucas, Hamdaoui, Nabila, Lafdil, Fouad, Haskó, György, Szabo, Csaba, Boulares, A. Hamid, Gao, Bin, Pacher, Pal
Published in Hepatology (Baltimore, Md.) (01.05.2014)
Published in Hepatology (Baltimore, Md.) (01.05.2014)
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Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types
Niu, Jing, Scheuerell, Christie, Mehrotra, Shailly, Karan, Sharon, Puhalla, Shannon, Kiesel, Brian F, Ji, Jiuping, Chu, Edward, Gopalakrishnan, Mathangi, Ivaturi, Vijay, Gobburu, Jogarao, Beumer, Jan H
Published in Journal of clinical pharmacology (01.08.2017)
Published in Journal of clinical pharmacology (01.08.2017)
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Modulation of Poly ADP Ribose Polymerase (PARP) Levels and Activity by Alcohol Binge-Like Drinking in Male Mice
Vallerini, Gian Paolo, Cheng, You-Hong, Chase, Kayla A., Sharma, Rajiv P., Kusumo, Handojo, Khakhkhar, Shivani, Feinstein, Douglas L., Guizzetti, Marina, Gavin, David P.
Published in Neuroscience (10.11.2020)
Published in Neuroscience (10.11.2020)
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MicroRNA expression and protein acetylation pattern in respiratory and limb muscles of Parp-1−/− and Parp-2−/− mice with lung cancer cachexia
Chacon-Cabrera, Alba, Fermoselle, Clara, Salmela, Ida, Yelamos, Jose, Barreiro, Esther
Published in Biochimica et biophysica acta (01.12.2015)
Published in Biochimica et biophysica acta (01.12.2015)
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Regulation of Myofibroblast Differentiation by Poly(ADP-Ribose) Polymerase 1
Hu, Biao, Wu, Zhe, Hergert, Polla, Henke, Craig A., Bitterman, Peter B., Phan, Sem H.
Published in The American journal of pathology (01.01.2013)
Published in The American journal of pathology (01.01.2013)
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Expression of nuclear matrix proteins binding matrix attachment regions in prostate cancer. PARP‐1: New player in tumor progression
Barboro, Paola, Ferrari, Nicoletta, Capaia, Matteo, Petretto, Andrea, Salvi, Sandra, Boccardo, Simona, Balbi, Cecilia
Published in International journal of cancer (01.10.2015)
Published in International journal of cancer (01.10.2015)
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Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents
Reiner, Thomas, Lacy, Jessica, Keliher, Edmund J., Yang, Katherine S., Ullal, Adeeti, Kohler, Rainer H., Vinegoni, Claudio, Weissleder, Ralph
Published in Neoplasia (New York, N.Y.) (01.03.2012)
Published in Neoplasia (New York, N.Y.) (01.03.2012)
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PARP-1 transcriptional activity is regulated by sumoylation upon heat shock
Martin, Nadine, Schwamborn, Klaus, Schreiber, Valérie, Werner, Andreas, Guillier, Christelle, Zhang, Xiang-Dong, Bischof, Oliver, Seeler, Jacob-S, Dejean, Anne
Published in The EMBO journal (18.11.2009)
Published in The EMBO journal (18.11.2009)
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Advanced oxidation protein products induce intestine epithelial cell death through a redox-dependent, c-jun N-terminal kinase and poly (ADP-ribose) polymerase-1-mediated pathway
Xie, F, Sun, S, Xu, A, Zheng, S, Xue, M, Wu, P, Zeng, J H, Bai, L
Published in Cell death & disease (01.01.2014)
Published in Cell death & disease (01.01.2014)
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Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney
Ebrahimkhani, Mohammad R., Daneshmand, Ali, Mazumder, Aprotim, Allocca, Mariacarmela, Calvo, Jennifer A., Abolhassani, Nona, Jhun, Iny, Muthupalani, Sureshkumar, Ayata, Cenk, Samson, Leona D.
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2014)
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