L-Asparaginase Conjugates from the Hyperthermophilic Archaea Thermococcus sibiricus with Improved Biocatalytic Properties
Dobryakova, Natalia V, Dumina, Maria V, Zhgun, Alexander A, Pokrovskaya, Marina V, Aleksandrova, Svetlana S, Zhdanov, Dmitry D, Kudryashova, Elena V
Published in International journal of molecular sciences (10.04.2024)
Published in International journal of molecular sciences (10.04.2024)
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Molecular Analysis of L-Asparaginases for Clarification of the Mechanism of Action and Optimization of Pharmacological Functions
Pokrovskaya, Marina V, Pokrovsky, Vadim S, Aleksandrova, Svetlana S, Sokolov, Nikolay N, Zhdanov, Dmitry D
Published in Pharmaceutics (09.03.2022)
Published in Pharmaceutics (09.03.2022)
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Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from Rhodospirillum rubrum by Conjugation with Chitosan-Based Cationic Polyelectrolytes
Dobryakova, Natalia V, Zhdanov, Dmitry D, Sokolov, Nikolay N, Aleksandrova, Svetlana S, Pokrovskaya, Marina V, Kudryashova, Elena V
Published in Pharmaceuticals (Basel, Switzerland) (27.03.2022)
Published in Pharmaceuticals (Basel, Switzerland) (27.03.2022)
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Correction: Plyasova et al. Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase. Pharmaceuticals 2020, 13 , 286
Plyasova, Anna A, Pokrovskaya, Marina V, Lisitsyna, Olga M, Pokrovsky, Vadim S, Alexandrova, Svetlana S, Hilal, Abdullah, Sokolov, Nikolay N, Zhdanov, Dmitry D
Published in Pharmaceuticals (Basel, Switzerland) (27.05.2024)
Published in Pharmaceuticals (Basel, Switzerland) (27.05.2024)
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Rhodospirillum rubrum L-Asparaginase Conjugates with Polyamines of Improved Biocatalytic Properties as a New Promising Drug for the Treatment of Leukemia
Dobryakova, Natalia V., Zhdanov, Dmitry D., Sokolov, Nikolay N., Aleksandrova, Svetlana S., Pokrovskaya, Marina V., Kudryashova, Elena V.
Published in Applied sciences (01.03.2023)
Published in Applied sciences (01.03.2023)
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Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase
Plyasova, Anna A, Pokrovskaya, Marina V, Lisitsyna, Olga M, Pokrovsky, Vadim S, Alexandrova, Svetlana S, Hilal, Abdullah, Sokolov, Nikolay N, Zhdanov, Dmitry D
Published in Pharmaceuticals (Basel, Switzerland) (30.09.2020)
Published in Pharmaceuticals (Basel, Switzerland) (30.09.2020)
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FTIR-based L-asparaginase activity assay enables continuous measurements in optically dense media including blood plasma
Kudryashova, Elena V., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Vinogradov, Alexander A., Sokolov, Nikolay N.
Published in Analytical biochemistry (01.06.2020)
Published in Analytical biochemistry (01.06.2020)
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Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase–Carbonic Anhydrase Dual-Hybrid Inhibitors
Plyasova, Anna A, Berrino, Emanuela, Khan, Irina I, Veselovsky, Alexander V, Pokrovsky, Vadim S, Angeli, Andrea, Ferraroni, Marta, Supuran, Claudiu T, Pokrovskaya, Marina V, Alexandrova, Svetlana S, Gladilina, Yulia A, Sokolov, Nikolay N, Hilal, Abdullah, Carta, Fabrizio, Zhdanov, Dmitry D
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes
Zhdanov, Dmitry D., Plyasova, Anna A., Gladilina, Yulia A., Pokrovsky, Vadim S., Grishin, Dmitry V., Grachev, Vladimir A., Orlova, Valentina S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Lobaeva, Tatiana A., Sokolov, Nikolay N.
Published in Biochemical and biophysical research communications (12.02.2019)
Published in Biochemical and biophysical research communications (12.02.2019)
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Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis
Zhdanov, Dmitry D., Gladilina, Yulia A., Grishin, Dmitry V., Grachev, Vladimir A., Orlova, Valentina S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Pokrovsky, Vadim S., Sokolov, Nikolai N.
Published in Molecular immunology (01.09.2018)
Published in Molecular immunology (01.09.2018)
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Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes
Zhdanov, Dmitry D., Plyasova, Anna A., Pokrovsky, Vadim S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Gladilina, Yulia A., Sokolov, Nikolay N.
Published in Biochimie (01.07.2020)
Published in Biochimie (01.07.2020)
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Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence
Zhdanov, Dmitry D., Gladilina, Yulia A., Pokrovsky, Vadim S., Grishin, Dmitry V., Grachev, Vladimir A., Orlova, Valentina S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Sokolov, Nikolay N.
Published in Cellular immunology (01.09.2018)
Published in Cellular immunology (01.09.2018)
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Endonuclease G modulates the alternative splicing of deoxyribonuclease 1 mRNA in human CD4+ T lymphocytes and prevents the progression of apoptosis
Zhdanov, Dmitry D., Gladilina, Yulia A., Pokrovsky, Vadim S., Grishin, Dmitry V., Grachev, Vladimir A., Orlova, Valentina S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Plyasova, Anna A., Sokolov, Nikolay N.
Published in Biochimie (01.02.2019)
Published in Biochimie (01.02.2019)
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Alternative splicing of telomerase catalytic subunit hTERT generated by apoptotic endonuclease EndoG induces human CD4+ T cell death
Zhdanov, Dmitry D., Vasina, Daria A., Grachev, Vladimir A., Orlova, Elena V., Orlova, Valentina S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Sokolov, Nikolai N.
Published in European journal of cell biology (01.10.2017)
Published in European journal of cell biology (01.10.2017)
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Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition
Zhdanov, Dmitry D., Pokrovsky, Vadim S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Eldarov, Mikhail A., Grishin, Dmitry V., Basharov, Marsel M., Gladilina, Yulia A., Podobed, Olga V., Sokolov, Nikolai N.
Published in Biochemical and biophysical research communications (14.10.2017)
Published in Biochemical and biophysical research communications (14.10.2017)
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Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L‐asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes
Zhdanov, Dmitry D., Pokrovsky, Vadim S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Eldarov, Mikhail A., Grishin, Dmitry V., Basharov, Marsel M., Gladilina, Yulia A., Podobed, Olga V., Sokolov, Nikolai N.
Published in Cancer medicine (Malden, MA) (01.11.2017)
Published in Cancer medicine (Malden, MA) (01.11.2017)
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L-Asparaginase Conjugates from the Hyperthermophilic Archaea IThermococcus sibiricus/I with Improved Biocatalytic Properties
Dobryakova, Natalia V, Dumina, Maria V, Zhgun, Alexander A, Pokrovskaya, Marina V, Aleksandrova, Svetlana S, Zhdanov, Dmitry D, Kudryashova, Elena V
Published in International journal of molecular sciences (01.04.2024)
Published in International journal of molecular sciences (01.04.2024)
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Journal Article
Rhodospirillum rubrum l-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition
Zhdanov, Dmitry D., Pokrovsky, Vadim S., Pokrovskaya, Marina V., Alexandrova, Svetlana S., Eldarov, Mikhail A., Grishin, Dmitry V., Basharov, Marsel M., Gladilina, Yulia A., Podobed, Olga V., Sokolov, Nikolai N.
Published in Biochemical and biophysical research communications (14.10.2017)
Published in Biochemical and biophysical research communications (14.10.2017)
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Journal Article
IRhodospirillum rubrum/I L-Asparaginase Conjugates with Polyamines of Improved Biocatalytic Properties as a New Promising Drug for the Treatment of Leukemia
Dobryakova, Natalia V, Zhdanov, Dmitry D, Sokolov, Nikolay N, Aleksandrova, Svetlana S, Pokrovskaya, Marina V, Kudryashova, Elena V
Published in Applied sciences (01.03.2023)
Published in Applied sciences (01.03.2023)
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