Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib
Dyczynski, Matheus, Yu, Yasmin, Otrocka, Magdalena, Parpal, Santiago, Braga, Tiago, Henley, Aine Brigette, Zazzi, Henric, Lerner, Mikael, Wennerberg, Krister, Viklund, Jenny, Martinsson, Jessica, Grandér, Dan, De Milito, Angelo, Pokrovskaja Tamm, Katja
Published in Cancer letters (28.10.2018)
Published in Cancer letters (28.10.2018)
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Journal Article
PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma
Vidarsdottir, Linda, Azimi, Alireza, Das, Ishani, Sigvaldadottir, Ingibjorg, Suryo Rahmanto, Aldwin, Petri, Andreas, Kauppinen, Sakari, Ingvar, Christian, Jönsson, Göran, Olsson, Håkan, Frostvik Stolt, Marianne, Tuominen, Rainer, Sangfelt, Olle, Pokrovskaja Tamm, Katja, Hansson, Johan, Grandér, Dan, Egyházi Brage, Suzanne, Johnsson, Per
Published in Scientific reports (26.05.2021)
Published in Scientific reports (26.05.2021)
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Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity enhancing cytarabine efficacy
Rudd, Sean G, Tsesmetzis, Nikolaos, Sanjiv, Kumar, Paulin, Cynthia BJ, Sandhow, Lakshmi, Kutzner, Juliane, Hed Myrberg, Ida, Bunten, Sarah S, Axelsson, Hanna, Zhang, Si Min, Rasti, Azita, Mäkelä, Petri, Coggins, Si'Ana A, Tao, Sijia, Suman, Sharda, Branca, Rui M, Mermelekas, Georgios, Wiita, Elisée, Lee, Sun, Walfridsson, Julian, Schinazi, Raymond F, Kim, Baek, Lehtiö, Janne, Rassidakis, Georgios Z, Pokrovskaja Tamm, Katja, Warpman‐Berglund, Ulrika, Heyman, Mats, Grandér, Dan, Lehmann, Sören, Lundbäck, Thomas, Qian, Hong, Henter, Jan‐Inge, Schaller, Torsten, Helleday, Thomas, Herold, Nikolas
Published in EMBO molecular medicine (06.03.2020)
Published in EMBO molecular medicine (06.03.2020)
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Journal Article
Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti‐tumor efficacy
Yu, Yasmin, Bogdan, Madhumita, Noman, Muhammad Zaeem, Parpal, Santiago, Bartolini, Elisabetta, Van Moer, Kris, Kleinendorst, Simone Caroline, Bilgrav Saether, Kristine, Trésaugues, Lionel, Silvander, Camilla, Lindström, Johan, Simeon, Jodi, Timson, Mary Jane, Al‐Hashimi, Hikmat, Smith, Bryan D., Flynn, Daniel L., Alexeyenko, Andrey, Viklund, Jenny, Andersson, Martin, Martinsson, Jessica, Pokrovskaja Tamm, Katja, De Milito, Angelo, Janji, Bassam
Published in Molecular oncology (01.08.2024)
Published in Molecular oncology (01.08.2024)
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Journal Article
Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets
Stratmann, Svea, Yones, Sara A., Mayrhofer, Markus, Norgren, Nina, Skaftason, Aron, Sun, Jitong, Smolinska, Karolina, Komorowski, Jan, Herlin, Morten Krogh, Sundström, Christer, Eriksson, Anna, Höglund, Martin, Palle, Josefine, Abrahamsson, Jonas, Jahnukainen, Kirsi, Munthe-Kaas, Monica Cheng, Zeller, Bernward, Tamm, Katja Pokrovskaja, Cavelier, Lucia, Holmfeldt, Linda
Published in Blood advances (09.02.2021)
Published in Blood advances (09.02.2021)
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Journal Article
Duplex Sequencing Uncovers Recurrent Low‐frequency Cancer‐associated Mutations in Infant and Childhood KMT2A‐rearranged Acute Leukemia
Pilheden, Mattias, Ahlgren, Louise, Hyrenius‐Wittsten, Axel, Gonzalez‐Pena, Veronica, Sturesson, Helena, Hansen Marquart, Hanne Vibeke, Lausen, Birgitte, Castor, Anders, Pronk, Cornelis Jan, Barbany, Gisela, Pokrovskaja Tamm, Katja, Fogelstrand, Linda, Lohi, Olli, Norén‐Nyström, Ulrika, Asklin, Johanna, Chen, Yilun, Song, Guangchun, Walsh, Michael, Ma, Jing, Zhang, Jinghui, Saal, Lao H., Gawad, Charles, Hagström‐Andersson, Anna K.
Published in HemaSphere (2022)
Published in HemaSphere (2022)
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Journal Article
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines
Leo, Isabelle Rose, Aswad, Luay, Stahl, Matthias, Kunold, Elena, Post, Frederik, Erkers, Tom, Struyf, Nona, Mermelekas, Georgios, Joshi, Rubin Narayan, Gracia-Villacampa, Eva, Östling, Päivi, Kallioniemi, Olli P., Tamm, Katja Pokrovskaja, Siavelis, Ioannis, Lehtiö, Janne, Vesterlund, Mattias, Jafari, Rozbeh
Published in Nature communications (30.03.2022)
Published in Nature communications (30.03.2022)
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Journal Article
Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children
Stratmann, Svea, Vesterlund, Mattias, Umer, Husen M., Eshtad, Saeed, Skaftason, Aron, Herlin, Morten Krogh, Sundström, Christer, Eriksson, Anna, Höglund, Martin, Palle, Josefine, Abrahamsson, Jonas, Jahnukainen, Kirsi, Munthe-Kaas, Monica Cheng, Zeller, Bernward, Tamm, Katja Pokrovskaja, Lindskog, Cecilia, Cavelier, Lucia, Lehtiö, Janne, Holmfeldt, Linda
Published in Leukemia (2023)
Published in Leukemia (2023)
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Journal Article
Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia
Bwanika, Henri Colyn, Leo, Isabelle Rose, Struyf, Nona, Talanti, Asimina, Aswad, Luay, Konnur, Aishwarya, Björklund, Ann-Charlotte, Heyman, Mats, Rassidakis, Georgios, Erkers, Tom, Seashore-Ludlow, Brinton, Jafari, Rozbeh, Pokrovskaja Tamm, Katja
Published in Scientific reports (18.02.2024)
Published in Scientific reports (18.02.2024)
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Journal Article
Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment
Dyczynski, Matheus, Vesterlund, Mattias, Björklund, Ann-Charlotte, Zachariadis, Vasilios, Janssen, Jerry, Gallart-Ayala, Hector, Daskalaki, Evangelia, Wheelock, Craig E., Lehtiö, Janne, Grandér, Dan, Tamm, Katja Pokrovskaja, Nilsson, Roland
Published in Cell death & disease (28.08.2018)
Published in Cell death & disease (28.08.2018)
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Journal Article
Mutational patterns and clonal evolution from diagnosis to relapse in pediatric acute lymphoblastic leukemia
Sayyab, Shumaila, Lundmark, Anders, Larsson, Malin, Ringnér, Markus, Nystedt, Sara, Marincevic-Zuniga, Yanara, Tamm, Katja Pokrovskaja, Abrahamsson, Jonas, Fogelstrand, Linda, Heyman, Mats, Norén-Nyström, Ulrika, Lönnerholm, Gudmar, Harila-Saari, Arja, Berglund, Eva C., Nordlund, Jessica, Syvänen, Ann-Christine
Published in Scientific reports (2021)
Published in Scientific reports (2021)
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Journal Article
Identification of novel small molecules that inhibit STAT3-dependent transcription and function
Kolosenko, Iryna, Yu, Yasmin, Busker, Sander, Dyczynski, Matheus, Liu, Jianping, Haraldsson, Martin, Palm Apergi, Caroline, Helleday, Thomas, Tamm, Katja Pokrovskaja, Page, Brent D G, Grander, Dan
Published in PloS one (21.06.2017)
Published in PloS one (21.06.2017)
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Journal Article
Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies
Daneshmanesh, Amir Hossein, Porwit, Anna, Hojjat-Farsangi, Mohammad, Jeddi-Tehrani, Mahmood, Tamm, Katja Pokrovskaja, Grandér, Dan, Lehmann, Sören, Norin, Stefan, Shokri, Fazel, Rabbani, Hodjattallah, Mellstedt, Håkan, Österborg, Anders
Published in Leukemia & lymphoma (01.04.2013)
Published in Leukemia & lymphoma (01.04.2013)
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Journal Article
Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression
Stratmann, Svea, Yones, Sara A., Garbulowski, Mateusz, Sun, Jitong, Skaftason, Aron, Mayrhofer, Markus, Norgren, Nina, Herlin, Morten Krogh, Sundström, Christer, Eriksson, Anna, Höglund, Martin, Palle, Josefine, Abrahamsson, Jonas, Jahnukainen, Kirsi, Munthe-Kaas, Monica Cheng, Zeller, Bernward, Tamm, Katja Pokrovskaja, Cavelier, Lucia, Komorowski, Jan, Holmfeldt, Linda
Published in Blood advances (11.01.2022)
Published in Blood advances (11.01.2022)
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Journal Article
An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a
Serviss, Jason T., Andrews, Nathanael, Van den Eynden, Jimmy, Richter, Felix Clemens, Houtman, Miranda, Vesterlund, Mattias, Schwarzmueller, Laura, Johnsson, Per, Larsson, Erik, Grandér †, Dan, Pokrovskaja Tamm, Katja
Published in Cell death & disease (03.07.2018)
Published in Cell death & disease (03.07.2018)
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Journal Article
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Herold, Nikolas, Rudd, Sean G, Ljungblad, Linda, Sanjiv, Kumar, Myrberg, Ida Hed, Paulin, Cynthia B J, Heshmati, Yaser, Hagenkort, Anna, Kutzner, Juliane, Page, Brent D G, Calderón-Montaño, José M, Loseva, Olga, Jemth, Ann-Sofie, Bulli, Lorenzo, Axelsson, Hanna, Tesi, Bianca, Valerie, Nicholas C K, Höglund, Andreas, Bladh, Julia, Wiita, Elisée, Sundin, Mikael, Uhlin, Michael, Rassidakis, Georgios, Heyman, Mats, Tamm, Katja Pokrovskaja, Warpman-Berglund, Ulrika, Walfridsson, Julian, Lehmann, Sören, Grandér, Dan, Lundbäck, Thomas, Kogner, Per, Henter, Jan-Inge, Helleday, Thomas, Schaller, Torsten
Published in Nature medicine (01.02.2017)
Published in Nature medicine (01.02.2017)
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