First‐in‐human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G‐protein‐biased sphingosine‐1 phosphate receptor‐1 agonist for endothelial protection
Bergougnan, Luc, Armani, Sara, Golor, Georg, Tardat, Agnes, Vitse, Olivier, Hurbin, Fabrice, Scemama, Michel, Poitiers, Franck, Radzik, David, Gaudin, Christophe, Hovsepian, Lionel, Muslin, Anthony J., Kirkesseli, Stephane, Deutsch, Paul, Parkar, Ashfaq A.
Published in British journal of clinical pharmacology (01.02.2021)
Published in British journal of clinical pharmacology (01.02.2021)
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Pharmacokinetic assessment of a five‐probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A
Turpault, Sandrine, Brian, William, Van Horn, Robert, Santoni, Alix, Poitiers, Franck, Donazzolo, Yves, Boulenc, Xavier
Published in British journal of clinical pharmacology (01.12.2009)
Published in British journal of clinical pharmacology (01.12.2009)
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A Randomized Study of the Relative Pharmacokinetics, Pharmacodynamics, and Safety of Alirocumab, a Fully Human Monoclonal Antibody to PCSK9, After Single Subcutaneous Administration at Three Different Injection Sites in Healthy Subjects
Lunven, Catherine, Paehler, Tobias, Poitiers, Franck, Brunet, Aurélie, Rey, Jacques, Hanotin, Corinne, Sasiela, William J.
Published in Cardiovascular therapeutics (01.12.2014)
Published in Cardiovascular therapeutics (01.12.2014)
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Relationship Between Low‐Density Lipoprotein Cholesterol, Free Proprotein Convertase Subtilisin/Kexin Type 9, and Alirocumab Levels After Different Lipid‐Lowering Strategies
Rey, Jacques, Poitiers, Franck, Paehler, Tobias, Brunet, Aurélie, DiCioccio, A. Thomas, Cannon, Christopher P., Surks, Howard K., Pinquier, Jean‐Louis, Hanotin, Corinne, Sasiela, William J.
Published in Journal of the American Heart Association (01.06.2016)
Published in Journal of the American Heart Association (01.06.2016)
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Effects of PCSK9 Inhibition With Alirocumab on Lipoprotein Metabolism in Healthy Humans
Reyes-Soffer, Gissette, Pavlyha, Marianna, Ngai, Colleen, Thomas, Tiffany, Holleran, Stephen, Ramakrishnan, Rajasekhar, Karmally, Wahida, Nandakumar, Renu, Fontanez, Nelson, Obunike, Joseph, Marcovina, Santica M, Lichtenstein, Alice H, Matthan, Nirupa R, Matta, James, Maroccia, Magali, Becue, Frederic, Poitiers, Franck, Swanson, Brian, Cowan, Lisa, Sasiela, William J, Surks, Howard K, Ginsberg, Henry N
Published in Circulation (New York, N.Y.) (24.01.2017)
Published in Circulation (New York, N.Y.) (24.01.2017)
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A RANDOMIZED STUDY OF THE RELATIVE BIOAVAILABILITY, PHARMACODYNAMICS, AND SAFETY OF ALIROCUMAB, A FULLY HUMAN MONOCLONAL ANTIBODY TO PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9, AFTER SINGLE SUBCUTANEOUS ADMINISTRATION AT THREE DIFFERENT INJECTION SITES IN HEALTHY SUBJECTS
Lunven, Catherine, Paehler, Tobias, Lewanczyk, Pascale, Poitiers, Franck, Brunet, Aurelie, Rey, Jacques, Hanotin, Corinne, Sasiela, Bill
Published in Journal of the American College of Cardiology (01.04.2014)
Published in Journal of the American College of Cardiology (01.04.2014)
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RANDOMIZED, PARTIAL BLIND STUDY OF THE PHARMACODYNAMICS, PHARMACOKINETICS AND SAFETY OF MULTIPLE SUBCUTANEOUS DOSES OF ALIROCUMAB, A FULLY HUMAN MONOCLONAL ANTIBODY TO PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9, ADMINISTERED EVERY 4 WEEKS ALONE OR IN COMBINATION WITH EZETIMIBE OR FENOFIBRATE IN HEALTHY SUBJECTS
Rey, Jacques, Poitiers, Franck, Paehler, Tobias, Brunet, Aurelie, Pinquier, Jean-Louis, Hanotin, Corinne, Sasiela, Bill
Published in Journal of the American College of Cardiology (2014)
Published in Journal of the American College of Cardiology (2014)
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A Randomized Study of the Relative Pharmacokinetics, Pharmacodynamics, and Safety of Alirocumab, a Fully Human Monoclonal Antibody to PCSK 9, After Single Subcutaneous Administration at Three Different Injection Sites in Healthy Subjects
Lunven, Catherine, Paehler, Tobias, Poitiers, Franck, Brunet, Aurélie, Rey, Jacques, Hanotin, Corinne, Sasiela, William J.
Published in Cardiovascular therapeutics (01.12.2014)
Published in Cardiovascular therapeutics (01.12.2014)
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Journal Article
RANDOMIZED, PARTIAL BLIND STUDY OF THE PHARMACODYNAMICS, PHARMACOKINETICS AND SAFETY OF MULTIPLE SUBCUTANEOUS DOSES OF ALIROCUMAB, A FULLY HUMAN MONOCLONAL ANTIBODY TO PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9, ADMINISTERED EVERY 4 WEEKS ALONE OR IN COMBINATION WITH EZETIMIBE OR FENOFIBRATE IN HEALTHY SUBJECTS
Rey, Jacques, Poitiers, Franck, Paehler, Tobias, Brunet, Aurelie, Pinquier, Jean-Louis, Hanotin, Corinne, Sasiela, Bill
Published in Journal of the American College of Cardiology (01.04.2014)
Published in Journal of the American College of Cardiology (01.04.2014)
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Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ9‐tetrahydrocannabinol‐induced central nervous system and heart rate effects in humans
Klumpers, Linda E., Roy, Christine, Ferron, Geraldine, Turpault, Sandrine, Poitiers, Franck, Pinquier, Jean‐Louis, Hasselt, Johan G. C., Zuurman, Lineke, Erwich, Frank A. S., Gerven, Joop M. A.
Published in British journal of clinical pharmacology (01.07.2013)
Published in British journal of clinical pharmacology (01.07.2013)
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Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ 9 ‐tetrahydrocannabinol‐induced central nervous system and heart rate effects in humans
Klumpers, Linda E., Roy, Christine, Ferron, Geraldine, Turpault, Sandrine, Poitiers, Franck, Pinquier, Jean‐Louis, van Hasselt, Johan G. C., Zuurman, Lineke, Erwich, Frank A. S., van Gerven, Joop M. A.
Published in British journal of clinical pharmacology (01.07.2013)
Published in British journal of clinical pharmacology (01.07.2013)
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