Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
Pfirschke, Christina, Engblom, Camilla, Rickelt, Steffen, Cortez-Retamozo, Virna, Garris, Christopher, Pucci, Ferdinando, Yamazaki, Takahiro, Poirier-Colame, Vichnou, Newton, Andita, Redouane, Younes, Lin, Yi-Jang, Wojtkiewicz, Gregory, Iwamoto, Yoshiko, Mino-Kenudson, Mari, Huynh, Tiffany G., Hynes, Richard O., Freeman, Gordon J., Kroemer, Guido, Zitvogel, Laurence, Weissleder, Ralph, Pittet, Mikael J.
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Published in Immunity (Cambridge, Mass.) (16.02.2016)
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Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
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Published in Science (American Association for the Advancement of Science) (05.01.2018)
Published in Science (American Association for the Advancement of Science) (05.01.2018)
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Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
Vétizou, Marie, Pitt, Jonathan M., Daillère, Romain, Lepage, Patricia, Waldschmitt, Nadine, Flament, Caroline, Rusakiewicz, Sylvie, Routy, Bertrand, Roberti, Maria P., Duong, Connie P. M., Poirier-Colame, Vichnou, Roux, Antoine, Becharef, Sonia, Formenti, Silvia, Golden, Encouse, Cording, Sascha, Eberl, Gerard, Schlitzer, Andreas, Ginhoux, Florent, Mani, Sridhar, Yamazaki, Takahiro, Jacquelot, Nicolas, Enot, David P., Bérard, Marion, Nigou, Jérôme, Opolon, Paule, Eggermont, Alexander, Woerther, Paul-Louis, Chachaty, Elisabeth, Chaput, Nathalie, Robert, Caroline, Mateus, Christina, Kroemer, Guido, Raoult, Didier, Boneca, Ivo Gomperts, Carbonnel, Franck, Chamaillard, Mathias, Zitvogel, Laurence
Published in Science (American Association for the Advancement of Science) (27.11.2015)
Published in Science (American Association for the Advancement of Science) (27.11.2015)
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Immune Infiltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors
RUSAKIEWICZ, Sylvie, SEMERARO, Michaela, CHAIGNEAU, Loic, LE BRUN-LY, Valérie, DUBREUIL, Patrice, CREMER, Isabelle, CAIGNARD, Anne, POIRIER-COLAME, Vichnou, CHABA, Kariman, FLAMENT, Caroline, HALAMA, Niels, JÄGER, Dirk, SARABI, Matthieu, EGGERMONT, Alexander, BONVALOT, Sylvie, COMMO, Frédéric, TERRIER, Philippe, OPOLON, Paule, EMILE, Jean-François, COINDRE, Jean-Michel, KROEMER, Guido, CHAPUT, Nathalie, LE CESNE, Axel, DESBOIS, Mélanie, BLAY, Jean-Yves, ZITVOGEL, Laurence, LOCHER, Clara, MENDEZ, Rosa, VIMOND, Nadège, CONCHA, Angel, GARRIDO, Federico, ISAMBERT, Nicolas
Published in Cancer research (Chicago, Ill.) (15.06.2013)
Published in Cancer research (Chicago, Ill.) (15.06.2013)
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Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors
Delahaye, Nicolas F, Rusakiewicz, Sylvie, Martins, Isabelle, Ménard, Cédric, Roux, Stephan, Lyonnet, Luc, Paul, Pascale, Sarabi, Matthieu, Chaput, Nathalie, Semeraro, Michaela, Minard-Colin, Véronique, Poirier-Colame, Vichnou, Chaba, Kariman, Flament, Caroline, Baud, Véronique, Authier, Hélène, Kerdine-Römer, Saadia, Pallardy, Marc, Cremer, Isabelle, Peaudecerf, Laetitia, Rocha, Bénédita, Valteau-Couanet, Dominique, Gutierrez, Javier Celis, Nunès, Jacques A, Commo, Frédéric, Bonvalot, Sylvie, Ibrahim, Nicolas, Terrier, Philippe, Opolon, Paule, Bottino, Cristina, Moretta, Alessandro, Tavernier, Jan, Rihet, Pascal, Coindre, Jean-Michel, Blay, Jean-Yves, Isambert, Nicolas, Emile, Jean-François, Vivier, Eric, Lecesne, Axel, Kroemer, Guido, Zitvogel, Laurence
Published in Nature Medicine (01.06.2011)
Published in Nature Medicine (01.06.2011)
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Combined evaluation of LC3B puncta and HMGB1 expression predicts residual risk of relapse after adjuvant chemotherapy in breast cancer
Ladoire, Sylvain, Penault-Llorca, Frédérique, Senovilla, Laura, Dalban, Cécile, Enot, David, Locher, Clara, Prada, Nicole, Poirier-Colame, Vichnou, Chaba, Kariman, Arnould, Laurent, Ghiringhelli, François, Fumoleau, Pierre, Spielmann, Marc, Delaloge, Suzette, Poillot, Marie Laure, Arveux, Patrick, Goubar, Aicha, Andre, Fabrice, Zitvogel, Laurence, Kroemer, Guido
Published in Autophagy (03.10.2015)
Published in Autophagy (03.10.2015)
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Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy
Vacchelli, Erika, Semeraro, Michaela, Enot, David P, Chaba, Kariman, Poirier Colame, Vichnou, Dartigues, Peggy, Perier, Aurelie, Villa, Irene, Rusakiewicz, Sylvie, Gronnier, Caroline, Goéré, Diane, Mariette, Christophe, Zitvogel, Laurence, Kroemer, Guido
Published in Oncotarget (28.08.2015)
Published in Oncotarget (28.08.2015)
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Potent Immunomodulatory Effects of the Trifunctional Antibody Catumaxomab
GOERE, Diane, FLAMENT, Caroline, ZITVOGEL, Laurence, RUSAKIEWICZ, Sylvie, POIRIER-COLAME, Vichnou, KEPP, Oliver, MARTINS, Isabelle, PESQUET, Julien, EGGERMONT, Alexander, ELIAS, Dominique, CHAPUT, Nathalie
Published in Cancer research (Chicago, Ill.) (01.08.2013)
Published in Cancer research (Chicago, Ill.) (01.08.2013)
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Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma
Jacquelot, Nicolas, Enot, David P, Flament, Caroline, Vimond, Nadège, Blattner, Carolin, Pitt, Jonathan M, Yamazaki, Takahiro, Roberti, María Paula, Daillère, Romain, Vétizou, Marie, Poirier-Colame, Vichnou, Semeraro, Michaëla, Caignard, Anne, Slingluff, Jr, Craig L, Sallusto, Federica, Rusakiewicz, Sylvie, Weide, Benjamin, Marabelle, Aurélien, Kohrt, Holbrook, Dalle, Stéphane, Cavalcanti, Andréa, Kroemer, Guido, Di Giacomo, Anna Maria, Maio, Michele, Wong, Phillip, Yuan, Jianda, Wolchok, Jedd, Umansky, Viktor, Eggermont, Alexander, Zitvogel, Laurence
Published in The Journal of clinical investigation (01.03.2016)
Published in The Journal of clinical investigation (01.03.2016)
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Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib
Arnault, Jean Philippe, Wechsler, Janine, Escudier, Bernard, Spatz, Alain, Tomasic, Gorana, Sibaud, Vincent, Aractingi, Selim, Grange, Jean-Didier, Poirier-Colame, Vichnou, Malka, David, Soria, Jean-Charles, Mateus, Christine, Robert, Caroline
Published in Journal of clinical oncology (10.08.2009)
Published in Journal of clinical oncology (10.08.2009)
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Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens
Ladoire, Sylvain, Chaba, Kariman, Martins, Isabelle, Sukkurwala, Abdul Qader, Adjemian, Sandy, Michaud, Mickaël, Poirier-Colame, Vichnou, Andreiuolo, Felipe, Galluzzi, Lorenzo, White, Eileen, Rosenfeldt, Mathias, Ryan, Kevin M., Zitvogel, Laurence, Kroemer, Guido
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Published in Autophagy (01.08.2012)
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Upregulation of intratumoral HLA class I and peritumoral Mx1 in ulcerated melanomas
Verver, Daniëlle, Poirier-Colame, Vichnou, Tomasic, Gorana, Cherif-Rebai, Khadija, Grunhagen, Dirk J., Verhoef, Cornelis, Suciu, Stefan, Robert, Caroline, Zitvogel, Laurence, Eggermont, Alexander M.M.
Published in Oncoimmunology (02.11.2019)
Published in Oncoimmunology (02.11.2019)
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Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects
Daillère, Romain, Vétizou, Marie, Waldschmitt, Nadine, Yamazaki, Takahiro, Isnard, Christophe, Poirier-Colame, Vichnou, Duong, Connie P.M., Flament, Caroline, Lepage, Patricia, Roberti, Maria Paula, Routy, Bertrand, Jacquelot, Nicolas, Apetoh, Lionel, Becharef, Sonia, Rusakiewicz, Sylvie, Langella, Philippe, Sokol, Harry, Kroemer, Guido, Enot, David, Roux, Antoine, Eggermont, Alexander, Tartour, Eric, Johannes, Ludger, Woerther, Paul-Louis, Chachaty, Elisabeth, Soria, Jean-Charles, Golden, Encouse, Formenti, Silvia, Plebanski, Magdalena, Madondo, Mutsa, Rosenstiel, Philip, Raoult, Didier, Cattoir, Vincent, Boneca, Ivo Gomperts, Chamaillard, Mathias, Zitvogel, Laurence
Published in Immunity (Cambridge, Mass.) (18.10.2016)
Published in Immunity (Cambridge, Mass.) (18.10.2016)
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Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
Sistigu, Antonella, Yamazaki, Takahiro, Vacchelli, Erika, Chaba, Kariman, Enot, David P, Adam, Julien, Vitale, Ilio, Goubar, Aicha, Baracco, Elisa E, Remédios, Catarina, Fend, Laetitia, Hannani, Dalil, Aymeric, Laetitia, Ma, Yuting, Niso-Santano, Mireia, Kepp, Oliver, Schultze, Joachim L, Tüting, Thomas, Belardelli, Filippo, Bracci, Laura, La Sorsa, Valentina, Ziccheddu, Giovanna, Sestili, Paola, Urbani, Francesca, Delorenzi, Mauro, Lacroix-Triki, Magali, Quidville, Virginie, Conforti, Rosa, Spano, Jean-Philippe, Pusztai, Lajos, Poirier-Colame, Vichnou, Delaloge, Suzette, Penault-Llorca, Frederique, Ladoire, Sylvain, Arnould, Laurent, Cyrta, Joanna, Dessoliers, Marie-Charlotte, Eggermont, Alexander, Bianchi, Marco E, Pittet, Mikael, Engblom, Camilla, Pfirschke, Christina, Préville, Xavier, Uzè, Gilles, Schreiber, Robert D, Chow, Melvyn T, Smyth, Mark J, Proietti, Enrico, André, Fabrice, Kroemer, Guido, Zitvogel, Laurence
Published in Nature Medicine (01.11.2014)
Published in Nature Medicine (01.11.2014)
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An Immunosurveillance Mechanism Controls Cancer Cell Ploidy
Senovilla, Laura, Vitale, Ilio, Martins, Isabelle, Tailler, Maximilien, Pailleret, Claire, Michaud, Mickaël, Galluzzi, Lorenzo, Adjemian, Sandy, Kepp, Oliver, Niso-Santano, Mireia, Shen, Shensi, Mariño, Guillermo, Criollo, Alfredo, Boilève, Alice, Job, Bastien, Ladoire, Sylvain, Ghiringhelli, François, Sistigu, Antonella, Yamazaki, Takahiro, Rello-Varona, Santiago, Locher, Clara, Poirier-Colame, Vichnou, Talbot, Monique, Valent, Alexander, Berardinelli, Francesco, Antoccia, Antonio, Ciccosanti, Fabiola, Fimia, Gian Maria, Piacentini, Mauro, Fueyo, Antonio, Messina, Nicole L., Li, Ming, Chan, Christopher J., Sigl, Verena, Pourcher, Guillaume, Ruckenstuhl, Christoph, Carmona-Gutierrez, Didac, Lazar, Vladimir, Penninger, Josef M., Madeo, Frank, López-Otín, Carlos, Smyth, Mark J., Zitvogel, Laurence, Castedo, Maria, Kroemer, Guido
Published in Science (American Association for the Advancement of Science) (28.09.2012)
Published in Science (American Association for the Advancement of Science) (28.09.2012)
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Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists
Yamazaki, T, Hannani, D, Poirier-Colame, V, Ladoire, S, Locher, C, Sistigu, A, Prada, N, Adjemian, S, Catani, J PP, Freudenberg, M, Galanos, C, André, F, Kroemer, G, Zitvogel, L
Published in Cell death and differentiation (01.01.2014)
Published in Cell death and differentiation (01.01.2014)
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Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients
Semeraro, Michaela, Rusakiewicz, Sylvie, Minard-Colin, Véronique, Delahaye, Nicolas F, Enot, David, Vély, Frédéric, Marabelle, Aurélien, Papoular, Benjamin, Piperoglou, Christelle, Ponzoni, Mirco, Perri, Patrizia, Tchirkov, Andrei, Matta, Jessica, Lapierre, Valérie, Shekarian, Tala, Valsesia-Wittmann, Sandrine, Commo, Frédéric, Prada, Nicole, Poirier-Colame, Vichnou, Bressac, Brigitte, Cotteret, Sophie, Brugieres, Laurence, Farace, Françoise, Chaput, Nathalie, Kroemer, Guido, Valteau-Couanet, Dominique, Zitvogel, Laurence
Published in Science translational medicine (15.04.2015)
Published in Science translational medicine (15.04.2015)
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The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer
Ladoire, Sylvain, Enot, David, Senovilla, Laura, Ghiringhelli, François, Poirier-Colame, Vichnou, Chaba, Kariman, Semeraro, Michaela, Chaix, Marie, Penault-Llorca, Frédérique, Arnould, Laurent, Poillot, Marie Laure, Arveux, Patrick, Delaloge, Suzette, Andre, Fabrice, Zitvogel, Laurence, Kroemer, Guido
Published in Autophagy (03.05.2016)
Published in Autophagy (03.05.2016)
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Low numbers of blood and salivary natural killer cells are associated with a better response to belimumab in primary Sjögren's syndrome: results of the BELISS study
Seror, Raphaèle, Nocturne, Gaétane, Lazure, Thierry, Hendel-Chavez, Houria, Desmoulins, Frédéric, Belkhir, Rakiba, Ravaud, Philippe, Benbijja, Mohcine, Poirier-Colame, Vichnou, Taoufik, Yacine, Mariette, Xavier
Published in Arthritis research & therapy (04.09.2015)
Published in Arthritis research & therapy (04.09.2015)
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NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome
Rusakiewicz, Sylvie, Nocturne, Gaetane, Lazure, Thierry, Semeraro, Michaela, Flament, Caroline, Caillat-Zucman, Sophie, Sène, Damien, Delahaye, Nicolas, Vivier, Eric, Chaba, Kariman, Poirier-Colame, Vichnou, Nordmark, Gunnel, Eloranta, Maija-Leena, Eriksson, Per, Theander, Elke, Forsblad-d'Elia, Helena, Omdal, Roald, Wahren-Herlenius, Marie, Jonsson, Roland, Rönnblom, Lars, Nititham, Joanne, Taylor, Kimberly E, Lessard, Christopher J, Sivils, Kathy L Moser, Gottenberg, Jacques-Eric, Criswell, Lindsey A, Miceli-Richard, Corinne, Zitvogel, Laurence, Mariette, Xavier
Published in Science translational medicine (2013)
Published in Science translational medicine (2013)
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