RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer
Hall, Adam E., Pohl, Sebastian Öther-Gee, Cammareri, Patrizia, Aitken, Stuart, Younger, Nicholas T., Raponi, Michela, Billard, Caroline V., Carrancio, Alfonso Bolado, Bastem, Aslihan, Freile, Paz, Haward, Fiona, Adams, Ian R., Caceres, Javier F., Preyzner, Paula, von Kriegsheim, Alex, Dunlop, Malcolm G., Din, Farhat V., Myant, Kevin B.
Published in Nature communications (19.05.2022)
Published in Nature communications (19.05.2022)
Get full text
Journal Article
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways
Gudiño, Victoria, Pohl, Sebastian Öther-Gee, Billard, Caroline V., Cammareri, Patrizia, Bolado, Alfonso, Aitken, Stuart, Stevenson, David, Hall, Adam E., Agostino, Mark, Cassidy, John, Nixon, Colin, von Kriegsheim, Alex, Freile, Paz, Popplewell, Linda, Dickson, George, Murphy, Laura, Wheeler, Ann, Dunlop, Malcolm, Din, Farhat, Strathdee, Douglas, Sansom, Owen J., Myant, Kevin B.
Published in Nature communications (20.04.2021)
Published in Nature communications (20.04.2021)
Get full text
Journal Article
Design, Synthesis, and Biological Evaluation of SSE1806, a Microtubule Destabilizer That Overcomes Multidrug Resistance
Firdous, Farhat, Riaz, Sharon, Furqan, Muhammad, Fozail, Salman, Fatima, Khushboo, Pohl, Sebastian Öther-Gee, Doleschall, Nora Julia, Myant, Kevin B., Kahfi, Jordan, Emwas, Abdul-Hamid, Jaremko, Mariusz, Chotana, Ghayoor Abbas, Saleem, Rahman Shah Zaib, Faisal, Amir
Published in ACS medicinal chemistry letters (12.10.2023)
Published in ACS medicinal chemistry letters (12.10.2023)
Get full text
Journal Article
Synthesis and characterization of bis-amide SSE1917 as a microtubule-stabilizing anticancer agent
Iqbal, Sana, Firdous, Farhat, Furqan, Muhammad, Bilal, Aishah, Fozail, Salman, Pohl, Sebastian Öther-Gee, Doleschall, Nora Julia, Myant, Kevin B., Singh, Upendra, Emwas, Abdul-Hamid, Jaremko, Mariusz, Faisal, Amir, Saleem, Rahman Shah Zaib
Published in Bioorganic chemistry (01.02.2024)
Published in Bioorganic chemistry (01.02.2024)
Get full text
Journal Article
Cross Talk Between Cellular Redox State and the Antiapoptotic Protein Bcl-2
Pohl, Sebastian Öther-Gee, Agostino, Mark, Dharmarajan, Arun, Pervaiz, Shazib
Published in Antioxidants & redox signaling (01.11.2018)
Published in Antioxidants & redox signaling (01.11.2018)
Get more information
Journal Article
Wnt Binding Affinity Prediction for Putative Frizzled-Type Cysteine-Rich Domains
Agostino, Mark, Pohl, Sebastian Öther-Gee
Published in International journal of molecular sciences (26.08.2019)
Published in International journal of molecular sciences (26.08.2019)
Get full text
Journal Article
Activation barriers in Class F G protein-coupled receptors revealed by umbrella sampling simulations
Agostino, Mark, Pohl, Sebastian Öther-Gee
Published in Organic & biomolecular chemistry (28.12.2020)
Published in Organic & biomolecular chemistry (28.12.2020)
Get full text
Journal Article
Gene expression analysis of heat-shock proteins and redox regulators reveals combinatorial prognostic markers in carcinomas of the gastrointestinal tract
Pohl, Sebastian Öther-Gee, Pervaiz, Shazib, Dharmarajan, Arun, Agostino, Mark
Published in Redox biology (01.07.2019)
Published in Redox biology (01.07.2019)
Get full text
Journal Article
The Role of Wnt Signalling in Angiogenesis
Olsen, Jun Jun, Pohl, Sebastian Öther-Gee, Deshmukh, Abhijeet, Visweswaran, Malini, Ward, Natalie C, Arfuso, Frank, Agostino, Mark, Dharmarajan, Arun
Published in Clinical biochemist reviews (01.11.2017)
Get full text
Published in Clinical biochemist reviews (01.11.2017)
Journal Article