IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization
Eissmann, Moritz F., Dijkstra, Christine, Jarnicki, Andrew, Phesse, Toby, Brunnberg, Jamina, Poh, Ashleigh R., Etemadi, Nima, Tsantikos, Evelyn, Thiem, Stefan, Huntington, Nicholas D., Hibbs, Margaret L., Boussioutas, Alex, Grimbaldeston, Michele A., Buchert, Michael, O’Donoghue, Robert J. J., Masson, Frederick, Ernst, Matthias
Published in Nature communications (21.06.2019)
Published in Nature communications (21.06.2019)
Get full text
Journal Article
RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis
Rickard, James A., O’Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby J., Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti, Silke, John
Published in Cell (22.05.2014)
Published in Cell (22.05.2014)
Get full text
Journal Article
A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development
O’Keefe, Ryan N., Carli, Annalisa L. E., Baloyan, David, Chisanga, David, Shi, Wei, Afshar-Sterle, Shoukat, Eissmann, Moritz F., Poh, Ashleigh R., Pal, Bhupinder, Seillet, Cyril, Locksley, Richard M., Ernst, Matthias, Buchert, Michael
Published in Nature communications (28.10.2023)
Published in Nature communications (28.10.2023)
Get full text
Journal Article
Mouse models for gastric cancer: Matching models to biological questions
Poh, Ashleigh R, O'Donoghue, Robert J J, Ernst, Matthias, Putoczki, Tracy L
Published in Journal of gastroenterology and hepatology (01.07.2016)
Published in Journal of gastroenterology and hepatology (01.07.2016)
Get full text
Journal Article
Editorial: Overcoming drug relapse and therapy resistance in NSCLC
Parakh, Sagun, Leong, Tracy L, Best, Sarah A, Poh, Ashleigh R
Published in Frontiers in oncology (07.06.2023)
Published in Frontiers in oncology (07.06.2023)
Get full text
Journal Article
Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
Huber, Anne, Allam, Amr H., Dijkstra, Christine, Thiem, Stefan, Huynh, Jennifer, Poh, Ashleigh R., Konecnik, Joshua, Jacob, Saumya P., Busuttil, Rita, Liao, Yang, Chisanga, David, Shi, Wei, Alorro, Mariah G., Forrow, Stephen, Tauriello, Daniele V.F., Batlle, Eduard, Boussioutas, Alex, Williams, David S., Buchert, Michael, Ernst, Matthias, Eissmann, Moritz F.
Published in Cell reports (Cambridge) (27.08.2024)
Published in Cell reports (Cambridge) (27.08.2024)
Get full text
Journal Article
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth
Thilakasiri, Pathum, Huynh, Jennifer, Poh, Ashleigh R, Tan, Chin Wee, Nero, Tracy L, Tran, Kelly, Parslow, Adam C, Afshar‐Sterle, Shoukat, Baloyan, David, Hannan, Natalie J, Buchert, Michael, Scott, Andrew Mark, Griffin, Michael DW, Hollande, Frederic, Parker, Michael W, Putoczki, Tracy L, Ernst, Matthias, Chand, Ashwini L
Published in EMBO molecular medicine (01.04.2019)
Published in EMBO molecular medicine (01.04.2019)
Get full text
Journal Article
Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer
Dmello, Rhynelle S., Palmieri, Michelle, Thilakasiri, Pathum S., Doughty, Larissa, Nero, Tracy L., Poh, Ashleigh R., To, Sarah Q., Lee, Erinna F., Douglas Fairlie, W., Mielke, Lisa, Parker, Michael W., Poon, Ivan K. H., Batlle, Eduard, Ernst, Matthias, Chand, Ashwini L.
Published in Cell death & disease (10.04.2024)
Published in Cell death & disease (10.04.2024)
Get full text
Journal Article
Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice
Poh, Ashleigh R, Dwyer, Amy R, Eissmann, Moritz F, Chand, Ashwini L, Baloyan, David, Boon, Louis, Murrey, Michael W, Whitehead, Lachlan, O'Brien, Megan, Lowell, Clifford A, Putoczki, Tracy L, Pixley, Fiona J, O'Donoghue, Robert J J, Ernst, Matthias
Published in Cancer immunology research (01.04.2020)
Published in Cancer immunology research (01.04.2020)
Get more information
Journal Article
Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer
Nguyen, Paul M., Dagley, Laura F., Preaudet, Adele, Lam, Nga, Giam, Maybelline, Fung, Ka Yee, Aizel, Kaheina, van Duijneveldt, Gemma, Tan, Chin Wee, Hirokawa, Yumiko, Yip, Hon Yan K., Love, Christopher G., Poh, Ashleigh R., Cruz, Akshay D’, Burstroem, Charlotte, Feltham, Rebecca, Abdirahman, Suad M., Meiselbach, Kristy, Low, Ronnie Ren Jie, Palmieri, Michelle, Ernst, Matthias, Webb, Andrew I., Burgess, Tony, Sieber, Oliver M., Bouillet, Philippe, Putoczki, Tracy L.
Published in Cell death and differentiation (01.02.2020)
Published in Cell death and differentiation (01.02.2020)
Get full text
Journal Article
A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma
Arulananda, Surein, O’Brien, Megan, Evangelista, Marco, Jenkins, Laura J., Poh, Ashleigh R., Walkiewicz, Marzena, Leong, Trishe, Mariadason, John M., Cebon, Jonathan, Balachander, Srividya B., Cidado, Justin R., Lee, Erinna F., John, Thomas, Fairlie, Walter D.
Published in Cell death discovery (28.05.2021)
Published in Cell death discovery (28.05.2021)
Get full text
Journal Article
Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages
Morrow, Riley J, Allam, Amr H, Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F, Jacob, Saumya P, O'Brien, Megan, Poh, Ashleigh R, Ernst, Matthias
Published in Cells (Basel, Switzerland) (17.12.2022)
Published in Cells (Basel, Switzerland) (17.12.2022)
Get full text
Journal Article