Tenebrio molitor as a Simple and Cheap Preclinical Pharmacokinetic and Toxicity Model
Brai, Annalaura, Poggialini, Federica, Vagaggini, Chiara, Pasqualini, Claudia, Simoni, Sauro, Francardi, Valeria, Dreassi, Elena
Published in International journal of molecular sciences (24.01.2023)
Published in International journal of molecular sciences (24.01.2023)
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Exploiting the bile acid binding protein as transporter of a Cholic Acid/Mirin bioconjugate for potential applications in liver cancer therapy
Tassone, Giusy, Maramai, Samuele, Paolino, Marco, Lamponi, Stefania, Poggialini, Federica, Dreassi, Elena, Petricci, Elena, Alcaro, Stefano, Pozzi, Cecilia, Romeo, Isabella
Published in Scientific reports (28.09.2024)
Published in Scientific reports (28.09.2024)
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Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth
Maresca, Luisa, Crivaro, Enrica, Migliorini, Francesca, Anichini, Giulia, Giammona, Alessandro, Pepe, Sara, Poggialini, Federica, Vagaggini, Chiara, Giannini, Giuseppe, Sestini, Serena, Borgognoni, Lorenzo, Lapucci, Andrea, Dreassi, Elena, Taddei, Maurizio, Manetti, Fabrizio, Petricci, Elena, Stecca, Barbara
Published in Pharmacological research (01.09.2023)
Published in Pharmacological research (01.09.2023)
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Serendipitous Identification of Azine Anticancer Agents Using a Privileged Scaffold Morphing Strategy
Cesarini, Silvia, Vicenti, Ilaria, Poggialini, Federica, Filippi, Silvia, Mancin, Eleonora, Fiaschi, Lia, De Marchi, Elisa, Giammarino, Federica, Vagaggini, Chiara, Bizzarri, Bruno Mattia, Saladino, Raffaele, Dreassi, Elena, Zazzi, Maurizio, Botta, Lorenzo
Published in Molecules (Basel, Switzerland) (01.04.2024)
Published in Molecules (Basel, Switzerland) (01.04.2024)
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Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity
Cesarini, Silvia, Vicenti, Ilaria, Poggialini, Federica, Secchi, Massimiliano, Giammarino, Federica, Varasi, Ilenia, Lodola, Camilla, Zazzi, Maurizio, Dreassi, Elena, Maga, Giovanni, Botta, Lorenzo, Saladino, Raffaele
Published in Molecules (Basel, Switzerland) (01.12.2022)
Published in Molecules (Basel, Switzerland) (01.12.2022)
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Sweet Cherry Extract as Permeation Enhancer of Tyrosine Kinase Inhibitors: A Promising Prospective for Future Oral Anticancer Therapies
Poggialini, Federica, Vagaggini, Chiara, Brai, Annalaura, Pasqualini, Claudia, Carbone, Anna, Musumeci, Francesca, Schenone, Silvia, Dreassi, Elena
Published in Pharmaceuticals (Basel, Switzerland) (01.10.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.10.2023)
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A Greener Technique for Microwave-Assisted O-Silylation and Silyl Ether Deprotection of Uridine and Other Substrates
Pasqualini, Claudia, Poggialini, Federica, Vagaggini, Chiara, Brai, Annalaura, Dreassi, Elena
Published in Chemistry an international journal (01.12.2022)
Published in Chemistry an international journal (01.12.2022)
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Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d ]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
Poggialini, Federica, Vagaggini, Chiara, Brai, Annalaura, Pasqualini, Claudia, Crespan, Emmanuele, Maga, Giovanni, Perini, Cecilia, Cabella, Noemi, Botta, Lorenzo, Musumeci, Francesca, Frosini, Maria, Schenone, Silvia, Dreassi, Elena
Published in Pharmaceutics (30.01.2023)
Published in Pharmaceutics (30.01.2023)
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The Pyrazolo[3,4- d ]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma
Rango, Enrico, Pastorino, Fabio, Brignole, Chiara, Mancini, Arianna, Poggialini, Federica, Di Maria, Salvatore, Zamperini, Claudio, Iovenitti, Giulia, Fallacara, Anna Lucia, Sabetta, Samantha, Clementi, Letizia, Valoti, Massimo, Schenone, Silvia, Angelucci, Adriano, Ponzoni, Mirco, Dreassi, Elena, Botta, Maurizio
Published in Biomedicines (12.03.2022)
Published in Biomedicines (12.03.2022)
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DEAD-Box Helicase DDX3X as a Host Target against Emerging Viruses: New Insights for Medicinal Chemical Approaches
Brai, Annalaura, Trivisani, Claudia Immacolata, Poggialini, Federica, Pasqualini, Claudia, Vagaggini, Chiara, Dreassi, Elena
Published in Journal of medicinal chemistry (11.08.2022)
Published in Journal of medicinal chemistry (11.08.2022)
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Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma
Vagaggini, Chiara, Brai, Annalaura, Bonente, Denise, Lombardi, Jessica, Poggialini, Federica, Pasqualini, Claudia, Barone, Virginia, Nicoletti, Claudio, Bertelli, Eugenio, Dreassi, Elena
Published in Journal of pharmaceutical and biomedical analysis (25.10.2023)
Published in Journal of pharmaceutical and biomedical analysis (25.10.2023)
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A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides
Ermini, Elena, Brai, Annalaura, Cini, Elena, Finetti, Federica, Giannini, Giuseppe, Padula, Daniele, Paradisi, Lucrezia, Poggialini, Federica, Trabalzini, Lorenza, Tolu, Paola, Taddei, Maurizio
Published in Chemical science (Cambridge) (24.04.2024)
Published in Chemical science (Cambridge) (24.04.2024)
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A Facile Access to Green Fluorescent Albumin Derivatives
Saletti, Mario, Paolino, Marco, Venditti, Jacopo, Bonechi, Claudia, Giuliani, Germano, Lamponi, Stefania, Tassone, Giusy, Boccia, Antonella, Botta, Chiara, Blancafort, Lluís, Poggialini, Federica, Vagaggini, Chiara, Cappelli, Andrea
Published in Chembiochem : a European journal of chemical biology (16.04.2024)
Published in Chembiochem : a European journal of chemical biology (16.04.2024)
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Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization
Bonomini, Anna, Felicetti, Tommaso, Pacetti, Martina, Bertagnin, Chiara, Coletti, Alice, Giammarino, Federica, De Angelis, Marta, Poggialini, Federica, Macchiarulo, Antonio, Sabatini, Stefano, Mercorelli, Beatrice, Nencioni, Lucia, Vicenti, Ilaria, Dreassi, Elena, Cecchetti, Violetta, Tabarrini, Oriana, Loregian, Arianna, Massari, Serena
Published in European journal of medicinal chemistry (05.11.2024)
Published in European journal of medicinal chemistry (05.11.2024)
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Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma
Di Maria, Salvatore, Passannanti, Raffaele, Poggialini, Federica, Vagaggini, Chiara, Serafinelli, Alessia, Bianchi, Elena, Governa, Paolo, Botta, Lorenzo, Maga, Giovanni, Crespan, Emmanuele, Manetti, Fabrizio, Dreassi, Elena, Musumeci, Francesca, Carbone, Anna, Schenone, Silvia
Published in European journal of medicinal chemistry (15.12.2024)
Published in European journal of medicinal chemistry (15.12.2024)
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Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzob1,4thiazepines potentially useful as neuroprotective agents
Maramai, Samuele, Saletti, Mario, Paolino, Marco, Giuliani, Germano, Cazzola, Jessica, Spaiardi, Paolo, Talpo, Francesca, Frosini, Maria, Pifferi, Alice, Ballarotto, Marco, Carotti, Andrea, Poggialini, Federica, Vagaggini, Chiara, Dreassi, Elena, Giorgi, Gianluca, Dondio, Giulio, Cappelli, Andrea, Rosario Biella, Gerardo, Anzini, Maurizio
Published in Bioorganic & medicinal chemistry (01.10.2024)
Published in Bioorganic & medicinal chemistry (01.10.2024)
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Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
Molinari, Alessio, Fallacara, Anna Lucia, Di Maria, Salvatore, Zamperini, Claudio, Poggialini, Federica, Musumeci, Francesca, Schenone, Silvia, Angelucci, Adriano, Colapietro, Alessandro, Crespan, Emmanuele, Kissova, Miroslava, Maga, Giovanni, Botta, Maurizio
Published in Bioorganic & medicinal chemistry letters (15.11.2018)
Published in Bioorganic & medicinal chemistry letters (15.11.2018)
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Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA
D'Agostino, Ilaria, Ardino, Claudia, Poli, Giulio, Sannio, Filomena, Lucidi, Massimiliano, Poggialini, Federica, Visaggio, Daniela, Rango, Enrico, Filippi, Silvia, Petricci, Elena, Visca, Paolo, Botta, Lorenzo, Docquier, Jean-Denis, Dreassi, Elena
Published in European journal of medicinal chemistry (05.03.2022)
Published in European journal of medicinal chemistry (05.03.2022)
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