The spatial and temporal regulation of the hormonal signal. Role of mitochondria in the formation of a protein complex required for the activation of cholesterol transport and steroids synthesis
Poderoso, Cecilia, Duarte, Alejandra, Cooke, Mariana, Orlando, Ulises, Gottifredi, Vanesa, Solano, Angela R., Lemos, Jose R., Podestá, Ernesto J.
Published in Molecular and cellular endocrinology (22.05.2013)
Published in Molecular and cellular endocrinology (22.05.2013)
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BRCA1 and BRCA2 mutations and clinical interpretation in 398 ovarian cancer patients: comparison with breast cancer variants in a similar population
Cardoso, Florencia C, Goncalves, Susana, Mele, Pablo G, Liria, Natalia C, Sganga, Leonardo, Diaz Perez, Ignacio, Podesta, Ernesto J, Solano, Angela R
Published in Human genomics (13.08.2018)
Published in Human genomics (13.08.2018)
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BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina
Solano, Angela R, Liria, Natalia C, Jalil, Fernanda S, Faggionato, Daniela M, Mele, Pablo G, Mampel, Alejandra, Cardoso, Florencia C, Podesta, Ernesto J
Published in Frontiers in oncology (21.08.2018)
Published in Frontiers in oncology (21.08.2018)
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MAPK Phosphatase-2 (MKP-2) Is Induced by hCG and Plays a Role in the Regulation of CYP11A1 Expression in MA-10 Leydig Cells
Gómez, Natalia V, Gorostizaga, Alejandra B, Mori Sequeiros García, María M, Brion, Laura, Acquier, Andrea, González-Calvar, Silvia I, Méndez, Carlos F, Podestá, Ernesto J, Paz, Cristina
Published in Endocrinology (Philadelphia) (01.04.2013)
Published in Endocrinology (Philadelphia) (01.04.2013)
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MAPK Phosphatase-1 (MKP-1) Expression Is Up-Regulated by hCG/cAMP and Modulates Steroidogenesis in MA-10 Leydig Cells
Brion, Laura, Maloberti, Paula M, Gomez, Natalia V, Poderoso, Cecilia, Gorostizaga, Alejandra B, Mori Sequeiros Garcia, Maria M, Acquier, Andrea B, Cooke, Mariana, Mendez, Carlos F, Podesta, Ernesto J, Paz, Cristina
Published in Endocrinology (Philadelphia) (01.07.2011)
Published in Endocrinology (Philadelphia) (01.07.2011)
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Tyrosine phosphatases as key regulators of StAR induction and cholesterol transport: SHP2 as a potential tyrosine phosphatase involved in steroid synthesis
Cooke, Mariana, Mele, Pablo, Maloberti, Paula, Duarte, Alejandra, Poderoso, Cecilia, Orlando, Ulises, Paz, Cristina, Cornejo Maciel, Fabiana, Podestá, Ernesto J.
Published in Molecular and cellular endocrinology (10.04.2011)
Published in Molecular and cellular endocrinology (10.04.2011)
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Hormonal activation of a kinase cascade localized at the mitochondria is required for StAR protein activity
Poderoso, Cecilia, Maloberti, Paula, Duarte, Alejandra, Neuman, Isabel, Paz, Cristina, Maciel, Fabiana Cornejo, Podesta, Ernesto J.
Published in Molecular and cellular endocrinology (05.03.2009)
Published in Molecular and cellular endocrinology (05.03.2009)
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revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases
Hunt, Mary C, Yamada, Junji, Maltais, Lois J, Wright, Mathew W, Podesta, Ernesto J, Alexson, Stefan E. H
Published in Journal of lipid research (01.09.2005)
Published in Journal of lipid research (01.09.2005)
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The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis
Castillo, Ana F., Orlando, Ulises, Helfenberger, Katia E., Poderoso, Cecilia, Podesta, Ernesto J.
Published in Molecular and cellular endocrinology (15.06.2015)
Published in Molecular and cellular endocrinology (15.06.2015)
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New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis
Castillo, Ana F., Orlando, Ulises D., Maloberti, Paula M., Prada, Jesica G., Dattilo, Melina A., Solano, Angela R., Bigi, María M., Ríos Medrano, Mayra A., Torres, María T., Indo, Sebastián, Caroca, Graciela, Contreras, Hector R., Marelli, Belkis E., Salinas, Facundo J., Salvetti, Natalia R., Ortega, Hugo H., Lorenzano Menna, Pablo, Szajnman, Sergio, Gomez, Daniel E., Rodríguez, Juan B., Podesta, Ernesto J.
Published in Cellular and molecular life sciences : CMLS (01.03.2021)
Published in Cellular and molecular life sciences : CMLS (01.03.2021)
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Adrenocorticotropin Induces Mitogen-Activated Protein Kinase Phosphatase 1 in Y1 Mouse Adrenocortical Tumor Cells
Bey, Paula, Gorostizaga, Alejandra B, Maloberti, Paula M, Lozano, Rocío Castilla, Poderoso, Cecilia, Maciel, Fabiana Cornejo, Podestá, Ernesto J, Paz, Cristina
Published in Endocrinology (Philadelphia) (01.04.2003)
Published in Endocrinology (Philadelphia) (01.04.2003)
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Mitochondrial fusion is essential for steroid biosynthesis
Duarte, Alejandra, Poderoso, Cecilia, Cooke, Mariana, Soria, Gastón, Cornejo Maciel, Fabiana, Gottifredi, Vanesa, Podestá, Ernesto J
Published in PloS one (21.09.2012)
Published in PloS one (21.09.2012)
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Regulatory mechanisms leading to differential Acyl-CoA synthetase 4 expression in breast cancer cells
Dattilo, Melina A., Benzo, Yanina, Herrera, Lucía M., Prada, Jesica G., Castillo, Ana F., Orlando, Ulises D., Podesta, Ernesto J., Maloberti, Paula M.
Published in Scientific reports (16.07.2019)
Published in Scientific reports (16.07.2019)
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Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer
Orlando, Ulises D, Castillo, Ana F, Dattilo, Melina A, Solano, Angela R, Maloberti, Paula M, Podesta, Ernesto J
Published in Oncotarget (15.12.2015)
Published in Oncotarget (15.12.2015)
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Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells
Maloberti, Paula M, Duarte, Alejandra B, Orlando, Ulises D, Pasqualini, María E, Solano, Angela R, López-Otín, Carlos, Podestá, Ernesto J
Published in PloS one (11.11.2010)
Published in PloS one (11.11.2010)
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Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells
Helfenberger, Katia E., Castillo, Ana F., Mele, Pablo G., Fiore, Ana, Herrera, Lucía, Finocchietto, Paola, Podestá, Ernesto J., Poderoso, Cecilia
Published in The Journal of steroid biochemistry and molecular biology (01.09.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.09.2019)
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Study of the Genetic Variants in BRCA1/2 and Non-BRCA Genes in a Population-Based Cohort of 2155 Breast/Ovary Cancer Patients, Including 443 Triple-Negative Breast Cancer Patients, in Argentina
Solano, Angela R., Mele, Pablo G., Jalil, Fernanda S., Liria, Natalia C., Podesta, Ernesto J., Gutiérrez, Leandro G.
Published in Cancers (31.05.2021)
Published in Cancers (31.05.2021)
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Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4
Cooke, Mariana, Orlando, Ulises, Maloberti, Paula, Podestá, Ernesto J., Maciel, Fabiana Cornejo
Published in Journal of lipid research (01.11.2011)
Published in Journal of lipid research (01.11.2011)
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The functional interaction between Acyl-CoA synthetase 4, 5-lipooxygenase and cyclooxygenase-2 controls tumor growth: a novel therapeutic target
Orlando, Ulises D, Garona, Juan, Ripoll, Giselle V, Maloberti, Paula M, Solano, Ángela R, Avagnina, Alejandra, Gomez, Daniel E, Alonso, Daniel F, Podestá, Ernesto J
Published in PloS one (13.07.2012)
Published in PloS one (13.07.2012)
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