Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer
Miller, Katelyn D, O'Connor, Seamus, Pniewski, Katherine A, Kannan, Toshitha, Acosta, Reyes, Mirji, Gauri, Papp, Sara, Hulse, Michael, Mukha, Dzmitry, Hlavaty, Sabina I, Salcido, Kelsey N, Bertolazzi, Fabrizio, Srikanth, Yellamelli V V, Zhao, Steven, Wellen, Kathryn E, Shinde, Rahul S, Claiborne, Daniel T, Kossenkov, Andrew, Salvino, Joseph M, Schug, Zachary T
Published in Nature cancer (01.10.2023)
Published in Nature cancer (01.10.2023)
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ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis
Hlavaty, Sabina I., Salcido, Kelsey N., Pniewski, Katherine A., Mukha, Dzmitry, Ma, Weili, Kannan, Toshitha, Cassel, Joel, Srikanth, Yellamelli V.V., Liu, Qin, Kossenkov, Andrew, Salvino, Joseph M., Chen, Qing, Schug, Zachary T.
Published in Cell reports (Cambridge)
Published in Cell reports (Cambridge)
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