Next-generation direct-acting influenza therapeutics
Toots, Mart, Plemper, Richard K.
Published in Translational research : the journal of laboratory and clinical medicine (01.06.2020)
Published in Translational research : the journal of laboratory and clinical medicine (01.06.2020)
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Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses
Yoon, Jeong-Joong, Toots, Mart, Lee, Sujin, Lee, Myung-Eun, Ludeke, Barbara, Luczo, Jasmina M, Ganti, Ketaki, Cox, Robert M, Sticher, Zachary M, Edpuganti, Vindya, Mitchell, Deborah G, Lockwood, Mark A, Kolykhalov, Alexander A, Greninger, Alexander L, Moore, Martin L, Painter, George R, Lowen, Anice C, Tompkins, Stephen M, Fearns, Rachel, Natchus, Michael G, Plemper, Richard K
Published in Antimicrobial agents and chemotherapy (01.08.2018)
Published in Antimicrobial agents and chemotherapy (01.08.2018)
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Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets
Cox, Robert M., Wolf, Josef D., Lieber, Carolin M., Sourimant, Julien, Lin, Michelle J., Babusis, Darius, DuPont, Venice, Chan, Julie, Barrett, Kim T., Lye, Diane, Kalla, Rao, Chun, Kwon, Mackman, Richard L., Ye, Chengjin, Cihlar, Tomas, Martinez-Sobrido, Luis, Greninger, Alexander L., Bilello, John P., Plemper, Richard K.
Published in Nature communications (05.11.2021)
Published in Nature communications (05.11.2021)
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A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness
Sego, T J, Aponte-Serrano, Josua O, Ferrari Gianlupi, Juliano, Heaps, Samuel R, Breithaupt, Kira, Brusch, Lutz, Crawshaw, Jessica, Osborne, James M, Quardokus, Ellen M, Plemper, Richard K, Glazier, James A
Published in PLoS computational biology (21.12.2020)
Published in PLoS computational biology (21.12.2020)
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4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses
Lieber, Carolin M, Aggarwal, Megha, Yoon, Jeong-Joong, Cox, Robert M, Kang, Hae-Ji, Sourimant, Julien, Toots, Mart, Johnson, Scott K, Jones, Cheryl A, Sticher, Zachary M, Kolykhalov, Alexander A, Saindane, Manohar T, Tompkins, Stephen M, Planz, Oliver, Painter, George R, Natchus, Michael G, Sakamoto, Kaori, Plemper, Richard K
Published in PLoS pathogens (17.04.2023)
Published in PLoS pathogens (17.04.2023)
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Promotion of virus assembly and organization by the measles virus matrix protein
Ke, Zunlong, Strauss, Joshua D., Hampton, Cheri M., Brindley, Melinda A., Dillard, Rebecca S., Leon, Fredrick, Lamb, Kristen M., Plemper, Richard K., Wright, Elizabeth R.
Published in Nature communications (30.04.2018)
Published in Nature communications (30.04.2018)
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SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model
Lieber, Carolin M., Cox, Robert M., Sourimant, Julien, Wolf, Josef D., Juergens, Kate, Phung, Quynh, Saindane, Manohar T., Smith, Meghan K., Sticher, Zachary M., Kalykhalov, Alexander A., Natchus, Michael G., Painter, George R., Sakamoto, Kaori, Greninger, Alexander L., Plemper, Richard K.
Published in Nature communications (29.07.2022)
Published in Nature communications (29.07.2022)
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Triggering the measles virus membrane fusion machinery
Brindley, Melinda A, Takeda, Makoto, Plattet, Philippe, Plemper, Richard K
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
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The Respiratory Syncytial Virus Fusion Protein and Neutrophils Mediate the Airway Mucin Response to Pathogenic Respiratory Syncytial Virus Infection
Stokes, Kate L, Currier, Michael G, Sakamoto, Kaori, Lee, Sujin, Collins, Peter L, Plemper, Richard K, Moore, Martin L
Published in Journal of Virology (01.09.2013)
Published in Journal of Virology (01.09.2013)
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Comparing molnupiravir and nirmatrelvir/ritonavir efficacy and the effects on SARS-CoV-2 transmission in animal models
Cox, Robert M., Lieber, Carolin M., Wolf, Josef D., Karimi, Amirhossein, Lieberman, Nicole A. P., Sticher, Zachary M., Roychoudhury, Pavitra, Andrews, Meghan K., Krueger, Rebecca E., Natchus, Michael G., Painter, George R., Kolykhalov, Alexander A., Greninger, Alexander L., Plemper, Richard K.
Published in Nature communications (07.08.2023)
Published in Nature communications (07.08.2023)
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Status of antiviral therapeutics against rabies virus and related emerging lyssaviruses
Du Pont, Venice, Plemper, Richard K, Schnell, Matthias J
Published in Current opinion in virology (01.04.2019)
Published in Current opinion in virology (01.04.2019)
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Influenza A virus resistance to 4'-fluorouridine coincides with viral attenuation in vitro and in vivo
Lieber, Carolin M, Kang, Hae-Ji, Aggarwal, Megha, Lieberman, Nicole A, Sobolik, Elizabeth B, Yoon, Jeong-Joong, Natchus, Michael G, Cox, Robert M, Greninger, Alexander L, Plemper, Richard K
Published in PLoS pathogens (01.02.2024)
Published in PLoS pathogens (01.02.2024)
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