Recent advances in prodrug-based nanoparticle therapeutics
Chen, Kuan-Ju, Plaunt, Adam J., Leifer, Franziska G., Kang, Jeong Yeon, Cipolla, David
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2021)
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2021)
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Journal Article
Inhaled Treprostinil-Prodrug Lipid Nanoparticle Formulations Provide Long-Acting Pulmonary Vasodilation
Leifer, Franziska G, Konicek, Donna M, Chen, Kuan-Ju, Plaunt, Adam J, Salvail, Dany, Laurent, Charles E, Corboz, Michel R, Li, Zhili, Chapman, Richard W, Perkins, Walter R, S Malinin, Vladimir
Published in Drug research (01.11.2018)
Published in Drug research (01.11.2018)
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Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension
Corboz, Michel R, Plaunt, Adam J, Malinin, Vladimir S, Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R, Chapman, Richard W
Published in The Journal of pharmacology and experimental therapeutics (01.10.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2022)
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Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension
Corboz, Michel R., Plaunt, Adam J., Malinin, Vladimir, Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R., Chapman, Richard W.
Published in European journal of pharmacology (05.02.2022)
Published in European journal of pharmacology (05.02.2022)
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Journal Article
Strategies to Overcome Biological Barriers Associated with Pulmonary Drug Delivery
Plaunt, Adam J, Nguyen, Tam L, Corboz, Michel R, Malinin, Vladimir S, Cipolla, David C
Published in Pharmaceutics (27.01.2022)
Published in Pharmaceutics (27.01.2022)
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Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension
Plaunt, Adam J, Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R, Chapman, Richard W, Li, Zhili, Cipolla, David C, Perkins, Walter R, Malinin, Vladimir S
Published in International journal of molecular sciences (07.01.2021)
Published in International journal of molecular sciences (07.01.2021)
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Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections
Plaunt, Adam J, Rose, Sasha J, Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P, Dorfman, Arielle, Smith, Barrett T, Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G, Corboz, Michel R, Chapman, Richard W, Cipolla, David, Perkins, Walter R, Malinin, Vladimir S, Konicek, Donna M
Published in Antimicrobial agents and chemotherapy (17.06.2021)
Published in Antimicrobial agents and chemotherapy (17.06.2021)
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Correction for Plaunt et al., “Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections”
Plaunt, Adam J., Rose, Sasha J., Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P., Dorfman, Arielle, Smith, Barrett T., Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G., Corboz, Michel R., Chapman, Richard W., Cipolla, David, Perkins, Walter R., Malinin, Vladimir S., Konicek, Donna M.
Published in Antimicrobial agents and chemotherapy (15.11.2022)
Published in Antimicrobial agents and chemotherapy (15.11.2022)
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Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug
Corboz, Michel R, Li, Zhili, Malinin, Vladimir, Plaunt, Adam J, Konicek, Donna M, Leifer, Franziska G, Chen, Kuan-Ju, Laurent, Charles E, Yin, Han, Biernat, Marzena C, Salvail, Dany, Zhuang, Jianguo, Xu, Fadi, Curran, Aidan, Perkins, Walter R, Chapman, Richard W
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
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Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA Infection
Konicek, Donna M, Plaunt, Adam J, Gharse, Sachin, Rose, Sasha J, Dorfman, Arielle, Sabnis, Amruta, Baker, Thomas, Gauani, Helena, Chun, Donald, Li, Zhili, Perkins, Walter R, Cipolla, David, Malinin, Vladimir S
Published in Pharmaceutics (31.08.2023)
Published in Pharmaceutics (31.08.2023)
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Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats
Chapman, Richard W., Li, Zhili, Chun, Donald, Gauani, Helena, Malinin, Vladimir, Plaunt, Adam J., Cipolla, David, Perkins, Walter R., Corboz, Michel R.
Published in Pulmonary pharmacology & therapeutics (01.02.2021)
Published in Pulmonary pharmacology & therapeutics (01.02.2021)
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Library Synthesis, Screening, and Discovery of Modified Zinc(II)-Bis(dipicolylamine) Probe for Enhanced Molecular Imaging of Cell Death
Plaunt, Adam J, Harmatys, Kara M, Wolter, William R, Suckow, Mark A, Smith, Bradley D
Published in Bioconjugate chemistry (16.04.2014)
Published in Bioconjugate chemistry (16.04.2014)
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Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil
Chapman, Richard W, Corboz, Michel R, Fernandez, Carlos, Sullivan, Eugene, Stautberg, Andy, Plaunt, Adam J, Konicek, Donna M, Malinin, Vladimir, Li, Zhili, Cipolla, David, Perkins, Walter
Published in ERJ open research (01.01.2021)
Published in ERJ open research (01.01.2021)
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Evaluation of [111In]-Labeled Zinc–Dipicolylamine Tracers for SPECT Imaging of Bacterial Infection
Rice, Douglas R., Plaunt, Adam J., Turkyilmaz, Serhan, Smith, Miles, Wang, Yuzhen, Rusckowski, Mary, Smith, Bradley D.
Published in Molecular imaging and biology (01.04.2015)
Published in Molecular imaging and biology (01.04.2015)
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Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil
Chapman, Richard W., Li, Zhili, Corboz, Michel R., Gauani, Helena, Plaunt, Adam J., Konicek, Donna M., Leifer, Franziska G., Laurent, Charles E., Yin, Han, Salvail, Dany, Dziak, Chad, Perkins, Walter R., Malinin, Vladimir
Published in Pulmonary pharmacology & therapeutics (01.04.2018)
Published in Pulmonary pharmacology & therapeutics (01.04.2018)
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Journal Article
Enhanced Cell Death Imaging Using Multivalent Zinc(II)-bis(dipicolylamine) Fluorescent Probes
Smith, Bryan A, Harmatys, Kara M, Xiao, Shuzhang, Cole, Erin L, Plaunt, Adam J, Wolter, William, Suckow, Mark A, Smith, Bradley D
Published in Molecular pharmaceutics (03.09.2013)
Published in Molecular pharmaceutics (03.09.2013)
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Chemically triggered release of 5-aminolevulinic acid from liposomes
Plaunt, Adam J, Harmatys, Kara M, Hendrie, Kyle A, Musso, Anthony J, Smith, Bradley D
Published in RSC advances (29.10.2014)
Published in RSC advances (29.10.2014)
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Selective non-covalent triggered release from liposomes
Plaunt, Adam J, Courbanou, Meghan B, Cuison, Katrina D, Harmatys, Kara M, Smith, Bradley D
Published in Chemical communications (Cambridge, England) (21.08.2012)
Published in Chemical communications (Cambridge, England) (21.08.2012)
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