Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth
Di Malta, Chiara, Siciliano, Diletta, Calcagni, Alessia, Monfregola, Jlenia, Punzi, Simona, Pastore, Nunzia, Eastes, Andrea N., Davis, Oliver, De Cegli, Rossella, Zampelli, Angela, Di Giovannantonio, Luca G., Nusco, Edoardo, Platt, Nick, Guida, Alessandro, Ogmundsdottir, Margret Helga, Lanfrancone, Luisa, Perera, Rushika M., Zoncu, Roberto, Pelicci, Pier Giuseppe, Settembre, Carmine, Ballabio, Andrea
Published in Science (American Association for the Advancement of Science) (16.06.2017)
Published in Science (American Association for the Advancement of Science) (16.06.2017)
Get full text
Journal Article
Immune dysfunction in Niemann‐Pick disease type C
Platt, Nick, Speak, Annelise O., Colaco, Alexandria, Gray, James, Smith, David A., Williams, Ian M., Wallom, Kerri‐Lee, Platt, Frances M.
Published in Journal of neurochemistry (01.01.2016)
Published in Journal of neurochemistry (01.01.2016)
Get full text
Journal Article
Inhibition of the Niemann-Pick C1 protein is a conserved feature of multiple strains of pathogenic mycobacteria
Weng, Yuzhe, Shepherd, Dawn, Liu, Yi, Krishnan, Nitya, Robertson, Brian D., Platt, Nick, Larrouy-Maumus, Gerald, Platt, Frances M.
Published in Nature communications (09.09.2022)
Published in Nature communications (09.09.2022)
Get full text
Journal Article
Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration
Palin, Karine, Cunningham, Colm, Forse, Penny, Perry, V. Hugh, Platt, Nick
Published in Neurobiology of disease (01.04.2008)
Published in Neurobiology of disease (01.04.2008)
Get full text
Journal Article
Implications for invariant natural killer T cell ligands due to the restricted presence of isoglobotrihexosylceramide in mammals
Speak, Anneliese O, Salio, Mariolina, Neville, David C.A, Fontaine, Josette, Priestman, David A, Platt, Nick, Heare, Tanya, Butters, Terry D, Dwek, Raymond A, Trottein, Francois, Exley, Mark A, Cerundolo, Vincenzo, Platt, Frances M
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2007)
Get full text
Journal Article
Defective iron homeostasis and hematological abnormalities in Niemann-Pick disease type C1
Chen, Oscar C W, Siebel, Stephan, Colaco, Alexandria, Nicoli, Elena-Raluca, Platt, Nick, Shepherd, Dawn, Newman, Stephanie, Armitage, Andrew E, Farhat, Nicole Y, Seligmann, George, Smith, Claire, Smith, David A, Abdul-Sada, Alaa, Jeyakumar, Mylvaganam, Drakesmith, Hal, Porter, Forbes D, Platt, Frances M
Published in Wellcome open research (01.01.2022)
Published in Wellcome open research (01.01.2022)
Get full text
Journal Article
Anti-TNF therapy for inflammatory bowel disease in patients with neurodegenerative Niemann-Pick disease Type C
Williams, Isabelle, Pandey, Sumeet, Haller, Wolfram, Huynh, Hien Quoc, Chan, Alicia, Düeker, Gesche, Bettels, Ruth, Peyrin-Biroulet, Laurent, Dike, Chinenye R, DeGeeter, Catherine, Smith, David, Al Eisa, Nada, Platt, Nick, Marquardt, Thorsten, Schwerd, Tobias, Platt, Frances M, Uhlig, Holm H
Published in Wellcome open research (2022)
Published in Wellcome open research (2022)
Get full text
Journal Article
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway
Fineran, Paul, Lloyd-Evans, Emyr, Lack, Nathan A., Platt, Nick, Davis, Lianne C., Morgan, Anthony J., Höglinger, Doris, Tatituri, Raju Venkata V., Clark, Simon, Williams, Ian M., Tynan, Patricia, Al Eisa, Nada, Nazarova, Evgeniya, Williams, Ann, Galione, Antony, Ory, Daniel S., Besra, Gurdyal S., Russell, David G., Brenner, Michael B., Sim, Edith, Platt, Frances M.
Published in Wellcome open research (21.06.2017)
Published in Wellcome open research (21.06.2017)
Get full text
Journal Article
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway
Fineran, Paul, Lloyd-Evans, Emyr, Lack, Nathan A, Platt, Nick, Davis, Lianne C, Morgan, Anthony J, Höglinger, Doris, Tatituri, Raju Venkata V, Clark, Simon, Williams, Ian M, Tynan, Patricia, Al Eisa, Nada, Nazarova, Evgeniya, Williams, Ann, Galione, Antony, Ory, Daniel S, Besra, Gurdyal S, Russell, David G, Brenner, Michael B, Sim, Edith, Platt, Frances M
Published in Wellcome open research (2017)
Published in Wellcome open research (2017)
Get full text
Journal Article
The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock
Haworth, R, Platt, N, Keshav, S, Hughes, D, Darley, E, Suzuki, H, Kurihara, Y, Kodama, T, Gordon, S
Published in The Journal of experimental medicine (03.11.1997)
Published in The Journal of experimental medicine (03.11.1997)
Get full text
Journal Article
Neurites undergoing Wallerian degeneration show an apoptotic-like process with annexin V positive staining and loss of mitochondrial membrane potential
Sievers, Caroline, Platt, Nick, Perry, V.Hugh, Coleman, Michael P, Conforti, Laura
Published in Neuroscience research (01.06.2003)
Published in Neuroscience research (01.06.2003)
Get full text
Journal Article
Sulfated Glycosphingolipid as Mediator of Phagocytosis: SM4s Enhances Apoptotic Cell Clearance and Modulates Macrophage Activity
Popovic, Zoran V, Sandhoff, Roger, Sijmonsma, Tjeerd P, Kaden, Sylvia, Jennemann, Richard, Kiss, Eva, Tone, Edgar, Autschbach, Frank, Platt, Nick, Malle, Ernst, Grone, Hermann-Josef
Published in The Journal of immunology (1950) (15.11.2007)
Published in The Journal of immunology (1950) (15.11.2007)
Get full text
Journal Article
Apoptotic Thymocyte Clearance in Scavenger Receptor Class A-Deficient Mice Is Apparently Normal
Platt, Nick, Suzuki, Hiroshi, Kodama, Tatsuhiko, Gordon, Siamon
Published in The Journal of immunology (1950) (01.05.2000)
Published in The Journal of immunology (1950) (01.05.2000)
Get full text
Journal Article
Macrophagic response to human mesenchymal stem cell and poly(ϵ-caprolactone) implantation in nonobese diabetic/severe combined immunodeficient mice
Xia, Zhidao, Ye, Hua, Choong, Cleo, Ferguson, David J. P., Platt, Nick, Cui, Zhanfeng, Triffitt, James T.
Published in Journal of biomedical materials research. Part A (01.12.2004)
Published in Journal of biomedical materials research. Part A (01.12.2004)
Get full text
Journal Article