Pulmonary fibrosis: Emerging diagnostic and therapeutic strategies
Selvarajah, Brintha, Platé, Manuela, Chambers, Rachel C.
Published in Molecular aspects of medicine (01.12.2023)
Published in Molecular aspects of medicine (01.12.2023)
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Journal Article
The promise of mTOR as a therapeutic target pathway in idiopathic pulmonary fibrosis
Platé, Manuela, Guillotin, Delphine, Chambers, Rachel C
Published in European respiratory review (30.09.2020)
Published in European respiratory review (30.09.2020)
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Journal Article
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis
Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.
Published in Nature communications (02.01.2019)
Published in Nature communications (02.01.2019)
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Journal Article
Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF
Mercer, Paul F, Woodcock, Hannah V, Eley, Jessica D, Platé, Manuela, Sulikowski, Michal G, Durrenberger, Pascal F, Franklin, Linda, Nanthakumar, Carmel B, Man, Yim, Genovese, Federica, McAnulty, Robin J, Yang, Shuying, Maher, Toby M, Nicholson, Andrew G, Blanchard, Andy D, Marshall, Richard P, Lukey, Pauline T, Chambers, Rachel C
Published in Thorax (01.08.2016)
Published in Thorax (01.08.2016)
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Journal Article
Congenital hypofibrinogenemia: Characterization of two missense mutations affecting fibrinogen assembly and secretion
Platè, Manuela, Asselta, Rosanna, Spena, Silvia, Spreafico, Marta, Fagoonee, Sharmila, Peyvandi, Flora, Tenchini, Maria Luisa, Duga, Stefano
Published in Blood cells, molecules, & diseases (01.11.2008)
Published in Blood cells, molecules, & diseases (01.11.2008)
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Journal Article
mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β 1 -induced collagen biosynthesis
Selvarajah, Brintha, Azuelos, Ilan, Platé, Manuela, Guillotin, Delphine, Forty, Ellen J, Contento, Greg, Woodcock, Hannah V, Redding, Matthew, Taylor, Adam, Brunori, Gino, Durrenberger, Pascal F, Ronzoni, Riccardo, Blanchard, Andy D, Mercer, Paul F, Anastasiou, Dimitrios, Chambers, Rachel C
Published in Science signaling (21.05.2019)
Published in Science signaling (21.05.2019)
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Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds
Butler, Colin R, Hynds, Robert E, Crowley, Claire, Gowers, Kate H.C, Partington, Leanne, Hamilton, Nicholas J, Cavalhos, Carla, Platé, Manuela, Samuel, Edward R, Burns, Alan J, Urbani, Luca, Birchall, Martin A, Lowdell, Mark W, De Coppi, Paolo, Janes, Sam M
Published in Biomaterials (01.04.2017)
Published in Biomaterials (01.04.2017)
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Journal Article
Genome-Wide Posttranscriptional Dysregulation by MicroRNAs in Human Asthma as Revealed by Frac-seq
Martinez-Nunez, Rocio T, Rupani, Hitasha, Platé, Manuela, Niranjan, Mahesan, Chambers, Rachel C, Howarth, Peter H, Sanchez-Elsner, Tilman
Published in The Journal of immunology (1950) (01.07.2018)
Published in The Journal of immunology (1950) (01.07.2018)
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The Use of High Resolution Melting (HRM) Analysis for Molecular Gene Defects of Type 3 Von Willebrand Disease: Studies of An Italian Cohort of 10 Patients
Solimando, Maria, Federici, Augusto B., Baronciani, Luciano, Mussetti, Alberto, Punzo, Margherita, La Marca, Silvia, Platè, Manuela, Asselta, Rosanna, Mannucci, Pier Mannuccio
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID-19 Study
Stewart, Iain, Jacob, Joseph, George, Peter M, Molyneaux, Philip L, Porter, Joanna C, Allen, Richard J, Aslani, Shahab, Baillie, J Kenneth, Barratt, Shaney L, Beirne, Paul, Bianchi, Stephen M, Blaikley, John F, Chalmers, James D, Chambers, Rachel C, Chadhuri, Nazia, Coleman, Christopher, Collier, Guilhem, Denneny, Emma K, Docherty, Annemarie, Elneima, Omer, Evans, Rachael A, Fabbri, Laura, Gibbons, Michael A, Gleeson, Fergus V, Gooptu, Bibek, Greening, Neil J, Guio, Beatriz Guillen, Hall, Ian P, Hanley, Neil A, Harris, Victoria, Harrison, Ewen M, Heightman, Melissa, Hillman, Toby E, Horsley, Alex, Houchen-Wolloff, Linzy, Jarrold, Ian, Johnson, Simon R, Jones, Mark G, Khan, Fasihul, Lawson, Rod, Leavy, Olivia, Lone, Nazir, Marks, Michael, McAuley, Hamish, Mehta, Puja, Parekh, Dhruv, Hanley, Karen Piper, Platé, Manuela, Pearl, John, Poinasamy, Krisnah, Quint, Jennifer K, Raman, Betty, Richardson, Matthew, Rivera-Ortega, Pilar, Saunders, Laura, Saunders, Ruth, Semple, Malcolm G, Sereno, Marco, Shikotra, Aarti, Simpson, A John, Singapuri, Amisha, Smith, David J F, Spears, Mark, Spencer, Lisa G, Stanel, Stefan, Thickett, David R, Thompson, A A Roger, Thorpe, Mathew, Walsh, Simon L F, Walker, Samantha, Weatherley, Nicholas David, Weeks, Mark E, Wild, Jim M, Wootton, Dan G, Brightling, Chris E, Ho, Ling-Pei, Wain, Louise V, Jenkins, Gisli R
Published in American journal of respiratory and critical care medicine (15.03.2023)
Published in American journal of respiratory and critical care medicine (15.03.2023)
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Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold
Crowley, Claire, Klanrit, Poramate, Butler, Colin R, Varanou, Aikaterini, Platé, Manuela, Hynds, Robert E, Chambers, Rachel C, Seifalian, Alexander M, Birchall, Martin A, Janes, Sam M
Published in Biomaterials (01.03.2016)
Published in Biomaterials (01.03.2016)
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Journal Article
Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis
Guillotin, Delphine, Taylor, Adam R, Platé, Manuela, Mercer, Paul F, Edwards, Lindsay M, Haggart, Ross, Miele, Gino, McAnulty, Robin J, Maher, Toby M, Hynds, Robert E, Jamal-Hanjani, Mariam, Marshall, Richard P, Fisher, Andrew J, Blanchard, Andy D, Chambers, Rachel C
Published in Thorax (01.01.2021)
Published in Thorax (01.01.2021)
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Journal Article
Molecular characterization of 7 patients affected by dys- or hypo-dysfibrinogenemia: Identification of a novel mutation in the fibrinogen Bbeta chain causing a gain of glycosylation
Asselta, Rosanna, Robusto, Michela, Platé, Manuela, Santoro, Cristina, Peyvandi, Flora, Duga, Stefano
Published in Thrombosis research (01.07.2015)
Published in Thrombosis research (01.07.2015)
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Single-cell analysis of bronchoalveolar cells in inflammatory and fibrotic post-COVID lung disease
Mehta, Puja, Sanz-Magallón Duque de Estrada, Blanca, Denneny, Emma K, Foster, Kane, Turner, Carolin T, Mayer, Andreas, Milighetti, Martina, Platé, Manuela, Worlock, Kaylee B, Yoshida, Masahiro, Brown, Jeremy S, Nikolić, Marko Z, Chain, Benjamin M, Noursadeghi, Mahdad, Chambers, Rachel C, Porter, Joanna C, Tomlinson, Gillian S
Published in Frontiers in immunology (17.05.2024)
Published in Frontiers in immunology (17.05.2024)
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Journal Article
Clinical and molecular characterisation of 21 patients affected by quantitative fibrinogen deficiency
Asselta, Rosanna, Platè, Manuela, Robusto, Michela, Borhany, Munira, Guella, Ilaria, Soldà, Giulia, Afrasiabi, Abdolreza, Menegatti, Marzia, Shamsi, Tahir, Peyvandi, Flora, Duga, Stefano
Published in Thrombosis and haemostasis (01.03.2015)
Published in Thrombosis and haemostasis (01.03.2015)
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Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis
Woodcock, Hannah V., Eley, Jessica D., Guillotin, Delphine, Platé, Manuela, Nanthakumar, Carmel B., Martufi, Matteo, Peace, Simon, Joberty, Gerard, Poeckel, Daniel, Good, Robert B., Taylor, Adam R., Zinn, Nico, Redding, Matthew, Forty, Ellen J., Hynds, Robert E., Swanton, Charles, Karsdal, Morten, Maher, Toby M., Fisher, Andrew, Bergamini, Giovanna, Marshall, Richard P., Blanchard, Andy D., Mercer, Paul F., Chambers, Rachel C.
Published in Nature communications (11.09.2020)
Published in Nature communications (11.09.2020)
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Journal Article
Why ERS Early Career Members should attend the International Congress 2019 in Madrid
Ubags, Niki, Platé, Manuela, Almendros, Isaac, Bartel, Sabine
Published in Breathe (Lausanne, Switzerland) (01.06.2019)
Published in Breathe (Lausanne, Switzerland) (01.06.2019)
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Journal Article
Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis
Contento, Greg, Wilson, Jo-Anne Am, Selvarajah, Brintha, Platé, Manuela, Guillotin, Delphine, Morales, Valle, Trevisani, Marcello, Pitozzi, Vanessa, Bianchi, Katiuscia, Chambers, Rachel C
Published in JCI insight (13.08.2024)
Published in JCI insight (13.08.2024)
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Journal Article
TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells
Smoktunowicz, Natalia, Platé, Manuela, Stern, Alejandro Ortiz, D'Antongiovanni, Vanessa, Robinson, Eifion, Chudasama, Vijay, Caddick, Stephen, Scotton, Chris J, Jarai, Gabor, Chambers, Rachel C
Published in Oncotarget (04.10.2016)
Published in Oncotarget (04.10.2016)
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Journal Article
Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID)
Wild, Jim M, Porter, Joanna C, Molyneaux, Philip L, George, Peter M, Stewart, Iain, Allen, Richard James, Aul, Raminder, Baillie, John Kenneth, Barratt, Shaney L, Beirne, Paul, Bianchi, Stephen M, Blaikley, John F, Brooke, Jonathan, Chaudhuri, Nazia, Collier, Guilhem, Denneny, Emma K, Docherty, Annemarie, Fabbri, Laura, Gibbons, Michael A, Gleeson, Fergus V, Gooptu, Bibek, Hall, Ian P, Hanley, Neil A, Heightman, Melissa, Hillman, Toby E, Johnson, Simon R, Jones, Mark G, Khan, Fasihul, Lawson, Rod, Mehta, Puja, Mitchell, Jane A, Platé, Manuela, Poinasamy, Krisnah, Quint, Jennifer K, Rivera-Ortega, Pilar, Semple, Malcolm, Simpson, A John, Smith, DJF, Spears, Mark, Spencer, LIsa G, Stanel, Stefan C, Thickett, David R, Thompson, A A Roger, Walsh, Simon LF, Weatherley, Nicholas D, Weeks, Mark Everard, Wootton, Dan G, Brightling, Chris E, Chambers, Rachel C, Ho, Ling-Pei, Jacob, Joseph, Piper Hanley, Karen, Wain, Louise V, Jenkins, R Gisli
Published in BMJ open respiratory research (01.09.2021)
Published in BMJ open respiratory research (01.09.2021)
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