Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision‐cut rat liver slices
Pushparajah, Daphnee S., Plant, Kathryn E., Plant, Nick J., Ioannides, Costas
Published in Environmental toxicology (01.03.2017)
Published in Environmental toxicology (01.03.2017)
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Journal Article
Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition
Alhumaydhi, Fahad A., de O. Lopes, Debora, Bordin, Diana L., Aljohani, Abdullah S. M., Lloyd, Cameron B., McNicholas, Michael D., Milano, Larissa, Charlier, Clara F., Villela, Izabel, Henriques, João Antonio P., Plant, Kathryn E., Elliott, Ruan M., Meira, Lisiane B.
Published in Scientific reports (10.02.2020)
Published in Scientific reports (10.02.2020)
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Journal Article
Inhibition of prenyltransferase activity by statins in both liver and muscle cell lines is not causative of cytotoxicity
Gee, Rowena H, Spinks, Jenny N, Malia, Jason M, Johnston, Jonathan D, Plant, Nick J, Plant, Kathryn E
Published in Toxicology (Amsterdam) (02.03.2015)
Published in Toxicology (Amsterdam) (02.03.2015)
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Journal Article
Phenethyl isothiocyanate, a naturally occurring phytochemical, is an antagonist of the aryl hydrocarbon receptor
Abdull Razis, Ahmad F., Konsue, Nattaya, Dervetzoglou, Myrto, Plant, Kathryn E., Plant, Nick, Ioannides, Costas
Published in Molecular nutrition & food research (01.03.2012)
Published in Molecular nutrition & food research (01.03.2012)
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Journal Article
The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor
Abdull Razis, Ahmad F., Hanlon, Natalya, Soltys, Ewa, Krizova, Veronika, Iori, Renato, Plant, Kathryn E., Plant, Nick, Ioannides, Costas
Published in Archives of toxicology (01.10.2012)
Published in Archives of toxicology (01.10.2012)
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Journal Article
The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1
Plant, Kathryn E., Anderson, Elizabeth, Simecek, Nicole, Brown, Richard, Forster, Sam, Spinks, Jenny, Toms, Nick, Gibson, G. Gordon, Lyon, Jon, Plant, Nick
Published in Toxicology and applied pharmacology (15.02.2009)
Published in Toxicology and applied pharmacology (15.02.2009)
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Journal Article
Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size
Pushparajah, Daphnee S., Umachandran, Meera, Nazir, Tariq, Plant, Kathryn E., Plant, Nick, Lewis, David F.V., Ioannides, Costas
Published in Toxicology in vitro (01.02.2008)
Published in Toxicology in vitro (01.02.2008)
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Journal Article
Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung
Pushparajah, Daphnee S., Umachandran, Meera, Plant, Kathryn E., Plant, Nick, Ioannides, Costas
Published in Mutagenesis (01.07.2008)
Published in Mutagenesis (01.07.2008)
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Journal Article
Intergenic Transcription in the Human β-Globin Gene Cluster
Plant, Kathryn E., Routledge, Samantha J. E., Proudfoot, Nick J.
Published in Molecular and Cellular Biology (01.10.2001)
Published in Molecular and Cellular Biology (01.10.2001)
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Journal Article
Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: studies using precision-cut tissue slices
Pushparajah, Daphnee S, Umachandran, Meera, Plant, Kathryn E, Plant, Nick, Ioannides, Costas
Published in Mutation research (02.04.2008)
Published in Mutation research (02.04.2008)
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Journal Article
Evaluation of the precision-cut liver and lung slice systems for the study of induction of CYP1, epoxide hydrolase and glutathione S -transferase activities
Pushparajah, Daphnee S, Umachandran, Meera, Plant, Kathryn E, Plant, Nick, Ioannides, Costas
Published in Toxicology (Amsterdam) (28.02.2007)
Published in Toxicology (Amsterdam) (28.02.2007)
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Journal Article
The human karyopherin α2 promoter is responsive to oxidative stress
Cheema, Manraj S, Gordon Gibson, G, Plant, Nick, Plant, Kathryn E
Published in Toxicology (Amsterdam) (2008)
Published in Toxicology (Amsterdam) (2008)
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Journal Article
Transcriptomic and phylogenetic analysis of Kpna genes: a family of nuclear import factors modulated in xenobiotic-mediated liver growth
Plant, Kathryn E, Everett, David M, Gordon Gibson, G, Lyon, Jon, Plant, Nick J
Published in Pharmacogenetics and genomics (01.09.2006)
Published in Pharmacogenetics and genomics (01.09.2006)
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Journal Article
Gene expression changes in rat liver following exposure to liver growth agents: role of Kupffer cells in xenobiotic-mediated liver growth
Crunkhorn, Sarah E, Plant, Kathryn E, Gibson, Gordon G, Kramer, Kerstin, Lyon, Jon, Lord, Peter G, Plant, Nick J
Published in Biochemical pharmacology (2004)
Published in Biochemical pharmacology (2004)
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